Geriatric oncology: cancer in senior adults (original) (raw)
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Geriatric Oncology: Past, Present, Future
Journal of Oncology Practice, 2008
During the last few years, the term "geriatric oncology" has received a lot of attention within the medical oncology community. This is due to recognition of the fact that the population of the United States is aging, and by the year 2030, 20% of the population will be older than 65 years of age, with those 85 years and older (ie, "the oldest old") encompassing the most rapidly growing group. 1 It is now well recognized that cancer is a major problem for older individuals. It is the second leading cause of death after heart disease in the United States and the leading cause of death among those 60 to 80 years of age. 2 Overall, age represents the single most important risk factor for developing cancer.
Bangladesh Medical Journal, 2009
We are growing old. In cancer care, there is no exception. Over one-half of all cancer patients in the United States are over age 60.Elderly represent 12% of the total world population. Over the next 25 years, more than 60% of all cancers diagnosed in people of 55 years old and older in Bangladesh As the number of elderly rise exponentially, we can expect growing numbers of elderly at risk for developing cancer. Without dramatic breakthroughs in cancer prevention and treatment, it will have a major impact on the magnitude of cancer problem. In the meantime, when we are growing old and facing cancer, several important realities need to address.
Geriatric oncology research to improve clinical care
Nature Reviews Clinical Oncology, 2012
| Cancer incidence increases with advanced age. The Cancer and Aging Research Group, in partnership with the National Institute on Aging and NCI, have summarized the gaps in knowledge in geriatric oncology and made recommendations to close these gaps. One recommendation was that the comprehensive geriatric assessment (CGA) should be incorporated within geriatric oncology research. Information from the CGA can be used to stratify patients into risk categories to better predict their tolerance of cancer treatment, and to follow functional consequences from treatment. Other recommendations were to design trials for older adults with study end points that address the needs of the older and/or vulnerable adult with cancer and to build a better infrastructure to accommodate the needs of older adults to improve their representation in trials. We use a case-based approach to highlight gaps in knowledge regarding the care of older adults with cancer, discuss our current state of knowledge of best practice patterns, and identify opportunities for research in geriatric oncology. More evidence regarding the treatment of older patients with cancer is urgently needed.
Mohile, Dale, Hurria, Geriatric Oncology Research to Improve Clinical Care, 2012
| Cancer incidence increases with advanced age. The Cancer and Aging Research Group, in partnership with the National Institute on Aging and NCI, have summarized the gaps in knowledge in geriatric oncology and made recommendations to close these gaps. One recommendation was that the comprehensive geriatric assessment (CGA) should be incorporated within geriatric oncology research. Information from the CGA can be used to stratify patients into risk categories to better predict their tolerance of cancer treatment, and to follow functional consequences from treatment. Other recommendations were to design trials for older adults with study end points that address the needs of the older and/or vulnerable adult with cancer and to build a better infrastructure to accommodate the needs of older adults to improve their representation in trials. We use a case-based approach to highlight gaps in knowledge regarding the care of older adults with cancer, discuss our current state of knowledge of best practice patterns, and identify opportunities for research in geriatric oncology. More evidence regarding the treatment of older patients with cancer is urgently needed.
Geriatric oncology: questions, answers and guidelines
memo - Magazine of European Medical Oncology, 2020
Summary Background With the aging of populations, the number of elderly persons with cancer will increase. Due to the high individuality of elderly persons and their varying patterns of resources and disabilities, cancer treatment for elderly cancer patients needs to be individually adapted. To achieve this, geriatric medicine has established the comprehensive geriatric assessment (CGA). This short review presents the evidence of feasibility and impact of CGA on cancer treatment in elderly patients, as recommended by the American Society of Clinical Oncology (ASCO) in 2018. Methods A systematic review of the literature and a Delphi Consensus with a panel of experts cooperated to compile the evidence for choosing the most adequate treatment for elderly cancer patients. Results There is evidence that CGA makes it possible to predict the occurrence of complications of chemotherapy and of health deterioration, as well as death within 1 year. Conclusion The ASCO has recognized the optimi...
Forum of Clinical Oncology, 2014
Cancer incidence increases with age. With an ageing population, the burden of cancer in older people is set to increase significantly in the coming decades. This is a heterogeneous group with wide variations in health and functional status separate from chronological age. Data suggest that historically this patient cohort have poorer outcomes and have been under-represented in clinical cancer trials. There is an emerging body of evidence to help guide treatment; however, ongoing research is needed to develop comprehensive evidence-based guidelines and identify treatment regimens, which are suitable for frailer patients. In this article, we review the current field of geriatric oncology. We highlight that age is not a contradiction to cancer treatment but geriatric assessment is needed to identify which treatment a patient may tolerate and benefit from.