The α2β1 integrin is a metastasis suppressor in mouse models and human cancer (original) (raw)

The alpha2 beta1 integrin is a metastasis suppressor in mouse models and human cancer

Bobby Madamanchi

Journal of Clinical Investigation, 2011

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Biphasic α2β1 Integrin Expression in Breast Cancer Metastasis to Bone

Julie Sterling

International Journal of Molecular Sciences

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Β1-INTEGRINS Signaling and Mammary Tumor Progression in Transgenic Mouse Models: Implications for Human Breast Cancer

William Muller

Breast Cancer Research, 2011

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Beta 1 integrin predicts survival in breast cancer: a clinicopathological and immunohistochemical study

Juliana S Zanetti

Diagnostic Pathology, 2012

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Integrin activation controls metastasis in human breast cancer

Paul Hughes, Mark Ginsberg

Proceedings of The National Academy of Sciences, 2001

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Integrin α3β1 Can Function to Promote Spontaneous Metastasis and Lung Colonization of Invasive Breast Carcinoma

M. Teoh-Fitzgerald

Molecular Cancer Research, 2014

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The integrin alpha 6 beta 1 promotes the survival of metastatic human breast carcinoma cells in mice

Reidar Albrechtsen

PubMed, 1997

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Genetic depletion and pharmacological targeting of αv integrin in breast cancer cells impairs metastasis in zebrafish and mouse xenograft models

Philippe Clément-lacroix

Breast Cancer Research, 2015

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Genetic depletion and pharmacological targeting of av integrin in breast cancer cells impairs metastasis in zebrafish and mouse xenograft models

Pentagrit Cro

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Down-Regulation of β1C Integrin in Breast Carcinomas Correlates with High Proliferative Fraction, High Histological Grade, and Larger Size

Giuseppe Viale

The American Journal of Pathology, 2000

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The relationship between bone metastasis from human breast cancer and integrin alpha(v)beta3 expression

Shin Takayama

Anticancer research

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Analysis of Integrin β4 Expression in Human Breast Cancer: Association with Basal-like Tumors and Prognostic Significance

Ashraf Khan

Clinical Cancer Research, 2008

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Tumour but not stromal expression of β3 integrin is essential, and is required early, for spontaneous dissemination of bone-metastatic breast cancer

Delphine Dénoyer

The Journal of pathology, 2014

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Growth and Metastasis of Murine Mammary Carcinomas 5 Integrins in β 3 and β A Direct Test of Potential Roles for Updated

Richard Hynes

2005

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Function of the Integrin α6β1 in Metastatic Breast Carcinoma Cells Assessed by Expression of a Dominant-Negative Receptor

Celia Chao

Cancer Research, 1996

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Targeted disruption of β1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction

John Hassell, William Muller

Cancer Cell, 2004

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Altered integrin expression and the malignant phenotype: the contribution of multiple integrated integrin receptors

Samuel Santoro

Journal of mammary gland biology and neoplasia, 1998

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A direct test of potential roles for beta3 and beta5 integrins in growth and metastasis of murine mammary carcinomas

Daniela Taverna

Cancer research, 2005

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Clinical and functional significance of α9β1 integrin expression in breast cancer: a novel cell-surface marker of the basal phenotype that promotes tumour cell invasion

Ian Hart

The Journal of Pathology, 2011

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Integrin α9β1 promotes malignant tumor growth and metastasis by potentiating epithelial-mesenchymal transition

Saji Oommen

Oncogene, 2013

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The role of αv-integrins in tumour progression and metastasis

Ian Hart

Seminars in Cancer Biology, 1996

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Integrin signaling in mammary epithelial cells and breast cancer

Sam Thiagalingam

2012

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Expression of estrogen receptor β increases integrin α1 and integrin β1 levels and enhances adhesion of breast cancer cells

Luisa Helguero

Journal of Cellular Physiology, 2010

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Integrin α2β1 decelerates proliferation, but promotes survival and invasion of prostate cancer cells

Marjaana Ojalill

Oncotarget, 2018

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Integrin subunits alpha5 and alpha6 regulate cell cycle by modulating the chk1 and Rb/E2F pathways to affect breast cancer metastasis

Sidhartha Hazari

2011

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Tumor αvβ3 Integrin Is a Therapeutic Target for Breast Cancer Bone Metastases

Yingshe Zhao

Cancer Research, 2007

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Expression level of integrin alpha 5 on tumour cells affects the rate of metastasis to the kidney

Sadao Shiosaka, yoshikazu takada

British Journal of Cancer

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Therapeutic targeting of integrin αvβ6 in breast cancer

Ian Hart

Journal of the National Cancer Institute, 2014

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Expression of integrin α3β1 and cyclooxygenase-2 (COX2) are positively correlated in human breast cancer

Paul Feustel

BMC Cancer, 2014

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Integrin-dependent response to laminin-511 regulates breast tumor cell invasion and metastasis

Normand Pouliot

International Journal of Cancer, 2012

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Integrin expression and glycosylation patterns regulate cell-matrix adhesion and alter with breast cancer progression

ritis shyanti

Biochemical and biophysical research communications, 2018

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Correlation of α2ß1 Integrin Expression with Histological Type and Hormonal Receptor Status in Breast Carcinomas

S. Lanzafame

Pathology - Research and Practice, 1996

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Function of the Integrin a6fJl in Metastatic Breast Carcinoma Cells Assessed by Expression of a Dominant-Negative Receptor

Celia Chao

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Tumor-specific expression of alphavbeta3 integrin promotes spontaneous metastasis of breast cancer to bone

Robin Anderson

Breast cancer research : BCR, 2006

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Integrin 6 4 Controls the Expression of Genes Associated with Cell Motility, Invasion, and Metastasis, Including S100A4/Metastasin

Min Chen

Journal of Biological Chemistry, 2008

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