Contributions by members of the TGFbeta superfamily to lens development (original) (raw)

Requirement for TGFβ receptor signaling during terminal lens fiber differentiation

Frank Lovicu

…, 2001

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Growth factor regulation of lens development

Frank Lovicu

Developmental Biology, 2005

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Peter Bishop Lecture: Growth factors in lens development and cataract: key roles for fibroblast growth factor and TGF-beta

Frank Lovicu

Clinical and Experimental Ophthalmology, 2000

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Disruption of Lens Fiber Cell Differentiation and Survival at Multiple Stages by Region-Specific Expression of Truncated FGF Receptors

Craig Stolen

Developmental Biology, 2000

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Fgf receptor signaling plays a role in lens induction

Sanjay Shirke

Development (Cambridge, England), 2001

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Fibroblast growth factor receptor signaling is essential for lens fiber cell differentiation

Sunder Sims-lucas

Developmental Biology, 2008

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Disregulation of ocular morphogenesis by lens-specific expression of FGF-3/Int-2 in transgenic mice

Chi-chao Chan

Developmental Biology, 1998

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Extracellular FGF-1 acts as a lens differentiation factor in transgenic mice. Development 121 : 505-514

Robert Friesel

Development

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Role of Cell and Matrix-Bound VEGF Isoforms in Lens Development

Tomoki Kurihara

Investigative Opthalmology & Visual Science, 2009

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The Role of Fibroblast Growth Factor in Eye Lens Development

Frank Lovicu

Annals of the New York Academy of Sciences, 1991

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Signaling through FGF receptor-2 is required for lens cell survival and for withdrawal from the cell cycle during lens fiber cell differentiation

Ruth Ashery-Padan

Developmental Dynamics, 2005

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Vascular Endothelial Growth Factor Expression and Signaling in the Lens

Jay Potts

Investigative Ophthalmology & Visual Science, 2003

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FGF Signaling in Chick Lens Development

anh Lê

Developmental Biology, 2001

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The type I BMP receptors, Bmpr1a and Acvr1, activate multiple signaling pathways to regulate lens formation

Vesa Kaartinen

Developmental Biology, 2009

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Functions of the Type 1 BMP Receptor Acvr1 (Alk2) in Lens Development: Cell Proliferation, Terminal Differentiation, and Survival

E. Bottinger, Vesa Kaartinen

Investigative Ophthalmology & Visual Science, 2008

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Overexpression of FGF-2 modulates fiber cell differentiation and survival in the mouse lens

Craig Stolen

Development (Cambridge, England), 1997

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Overlapping effects of different members of the FGF family on lens fiber differentiation in transgenic mice

Frank Lovicu

Development, 1998

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Insulin receptors and insulin-like growth factor I receptors are functional during organogenesis of the lens

L. Bassas

Molecular and Cellular Endocrinology, 1990

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TGFβ2 in Corneal Morphogenesis during Mouse Embryonic Development

Mohamad Azhar

Developmental Biology, 2001

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Bone morphogenetic protein signaling and the initiation of lens fiber cell differentiation

Teri Belecky-adams

Development, 2002

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Bmp signaling is required for development of primary lens fiber cells

Sonya Faber

Development, 2002

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Conditional deletion of β1-integrin from the developing lens leads to loss of the lens epithelial phenotype

Melinda Duncan

Developmental Biology, 2007

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Genetic and epigenetic mechanisms of gene regulation during lens development

Ales Cvekl, Melinda Duncan

Progress in Retinal and Eye Research, 2007

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Sef is a negative regulator of fiber cell differentiation in the ocular lens

Jessica Boros, Frank Lovicu

Differentiation, 2010

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FGF-2 Differentially Regulates Lens Epithelial Cell Behaviour during TGF-β-Induced EMT

Frank Lovicu

Cells

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RESULTS An Fgfr inhibitor suppresses expression of Pax 6 in the lens placode

Sonya Faber

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Development and use of the lens epithelial explant system to study lens differentiation and cataractogenesis

Frank Lovicu, Judith West-mays

Progress in Retinal and Eye Research, 2010

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Regional Differences in Tyrosine Kinase Receptor Signaling Components Determine Differential Growth Patterns in the Human Lens

Michael Wormstone

Investigative Ophthalmology & Visual Science, 2004

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The function of FGF signaling in the lens placode

Claudia Garcia

Developmental Biology, 2011

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