EFFECT OF DIODE LASER TREATMENT ON THE LEVEL OF IL-6 IN THE GINGIVAL CREVICULAR FLUID IN PATIENTS WITH CHRONIC PERIODONTITIS (original) (raw)
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Asian Pacific Journal of Health Sciences
The aim of this clinical trial was to examine the clinical and biochemical efficacy of diode laser as an adjunct to scaling and root planing (SRP). 30 subjects were selected on basis of inclusion criteria and were categorized into two groups. After selection of subjects, 15 patients were included under control group and 15 patients were included under test group randomly. Plaque index, gingival index, bleeding on probing, probing depth, and clinical attachment level were measured at baseline, 1 month and 3 months after treatment. Interleukin-6 (IL-6), component of gingival crevicular fluid were analyzed by enzyme-linked immunosorbent assay. Better outcome was observed in test group compared to control group in full-mouth clinical parameters. The total amount of IL-6 value was decreased (p<0.05) after treatment in both the test as well as the control groups (p<0.05). The Diode laser provided significant improvements in clinical parameters which showed its positive effect on non surgical periodontal therapy
International journal of health sciences
The aim of the study was to compare and evaluate the effect of diode laser as an adjunct to scaling and root planing and scaling and root planing alone on clinical parameters and Gingival Crevicular Fluid (GCF) interlukin-10 level in chronic periodontitis. Ten chronic periodontitis patients were selected. As it was a split mouth study, two sites with deepest pocket one in each quadrant were randomly assigned for scaling and root planing (SRP) and SRP+ diode laser treatment. Plaque index, gingival index, probing depth, and clinical attachment level were measured at baseline and at 3months after treatment. The GCF levels of interleukin-10 (IL-10) were analyzed by enzyme-linked immunosorbent assay. Test group showed significantly better outcome compared to the control group in all clinical parameters (PI, GI, PD and CAL). The total amount of IL-10 increased after treatment in both test and control groups. From baseline to three months, the SRP with Diode laser group demonstrated a subs...
Journal of lasers in medical sciences, 2014
INTRODUCTION Periodontitis is an inflammatory disease, for which, scaling and root planning(SRP) is the common approach for non-surgical control of inflammation. Using lasers is anotherapproach in the first phase of periodontal treatment for control of inflammation. Diode laserhas some beneficial effects such as acceleration of wound healing, promotion of angiogenesisand augmentation of growth factor release. Thus the aim of this study is the evaluation of diodelaser (980 nm) effect on gingival inflammation when it is used between the first and secondphase of periodontal treatment, in comparison with common treatment (SRP) modality alone. METHODS In this study, 21 patients with moderate to severe chronic periodontitis were selectedand divided in to control group (SRP) and test group (SRP + laser). Two months after the lastscaling and laser radiation, indexes including gingival level (GL), bleeding on probing (BOP)and modified gingival index (MGI) were recorded and compared with base...
Evaluation of the Effects of Diode (980 Nm) Laser on Gingival Inflammation after
2016
Introduction: Periodontitis is an inflammatory disease, for which, scaling and root planning (SRP) is the common approach for non-surgical control of inflammation. Using lasers is another approach in the first phase of periodontal treatment for control of inflammation. Diode laser has some beneficial effects such as acceleration of wound healing, promotion of angiogenesis and augmentation of growth factor release. Thus the aim of this study is the evaluation of diode
Photomedicine and Laser Surgery, 2012
Objective: The aim of this split-mouth, double blinded, short-term, controlled clinical trial was to study the effect of low-level laser therapy (LLLT) as an adjunct to scaling and root planing (SRP) for treatment of chronic periodontitis. Background data: LLLT is reported to improve the outcome of traditional SRP, but the evidence is still weak. Materials and methods: Sixteen patients with a probing pocket depth (PPD) of 4-6 mm involving at least three teeth in each quadrant were recruited for the study. Afterwards, SRP quadrants were randomly assigned for 10 sessions of LLLT. Results: Results showed that when compared to sites treated with SRP alone, those treated with SRP + LLLT (10 sessions, 830 nm, 100 mW, 3 J per point, 3 J/cm 2) exhibited greater reductions in PPD at 5 weeks and 3 months but not at 6 months. Further, SRP + LLLT-treated sites had a statistically significant increase in mean radiographic bone density when comparing 6-and 12-month data and overall from baseline to 12 months. There was a trend to reduce interleukin (IL)-1b but the difference between control and laser sites was not statistically significant. Conclusions: SRP combined with LLLT improved radiographic bone density and short-term PPD reduction in patients with chronic periodontitis, but did not significantly affect either the gingival crevicular fluid of IL-1b or the gingival or plaque index.
The journal of contemporary dental practice, 2024
Aim: This split-mouth randomized trial (RCT) aimed to assess the effect of diode laser on the clinical parameters in patients with periodontitis, compare the results with scaling and root planing (SRP) alone, and assess the implications of diode laser (DL) on plaque bacteria. Materials and methods: Seventeen periodontitis patients were randomly assigned into two equal groups based on the therapy delivered. Group I (control site) received just SRP at baseline, while group II (test site) received both SRP and DL irradiation. For both groups, the clinical periodontal parameters probing pocket depth (PPD), and clinical attachment level (CAL) were measured at baseline, 30 days, and 90 days. Microbiological amount was also measured at baseline, 30, and 90 days after periodontal treatment. The amounts of Aggregatibacter actinomycetemcomitans (A.a), Prevotella intermedia (Pr. intermedia), and Porphyromonas gingivalis (P. gingivalis) were determined using real-time PCR probing with specific bacterial primers. Results: In both groups, PPD and CAL showed statistically significant reductions at different time intervals (p < 0.05). No significant difference were observed in CAL values after 1 and 3 months in both test and control groups (p > 0.05). The mean values of the concentration of A.a, Pr. intermedia and P. gingivalis were lower in the case group as compared to the control group and the difference was statistically significant after 1 month (*p = 0.001). Clinical significance: According to this study, non-invasive laser treatment has the potential to improve clinical outcomes by lowering the quantity of A.a, Pr. intermedia and P. gingivalis. Conclusion: In both groups, a considerable decrease in the periodontal pathogens A.a, Pr. intermedia and P. gingivalis were discovered; however, the intergroup comparison was insignificant in relation to PD and CAL. The adjunctive treatment with diode laser showed better efficacy in ensuring a better periodontal treatment than SRP alone.
Journal of Contemporary Dentistry, 2019
To compare the clinical effects of diode laser (DL) as an adjunct to scaling and root planing (SRP) and SRP alone in the treatment of subjects with chronic periodontitis. Thirty subjects aged 25–54 years participated in this randomized split-mouth clinical study. All subjects with 60 selected sites were randomly divided into 2 equal groups depending on the treatment provided. Group I (control site): only SRP was performed at baseline and group II (test site): SRP along with DL irradiation was performed on day 7, 14, and 21. Clinical parameters plaque index (PI), gingival index (GI), bleeding index (BI), probing pocket depth (PPD), and clinical attachment level (CAL) were recorded at baseline and the end of 3 months for both groups. Mean values of PPD from baseline to 3 months between groups I and II on the mesial and distal aspect showed a high statistically significant difference (p < 0.02). Mean values of CAL from baseline to 3 months between two groups on distal and buccal asp...
Cumhuriyet Dental Journal, 2017
The aim of this study is to examine the clinical efficiency of diode laser periodontal pocket irradiation as an adjunct to conventional scaling and root planning (SRP) on periodontal parameters and halitosis. Material and Methods: In our randomized, controlled clinical trial, 40 patients with untreated chronic periodontitis were randomly separated into two group to receive SRP with laser (laser group n=20) or SRP solely (control group n=20). Plaque index (PI), gingival index (GI), probing pocket depth (PD), clinic attachment loss (CAL), bleeding on probing (BOP) and halitosis were recorded at baseline and 1st ,3rd and6th months after treatment by a periodontist. Results: Both treatment methods showed significant reductions in clinical parameters and halitosis levels compared to baseline. Conclusion: The present study indicates that compared to SRP solely, adjunctive applications of a 940-nm diode laser with SRP showed lower bleeding on probing and halitosis levels.
Journal of lasers in medical sciences, 2016
Introduction: The aim of this study was to evaluate the efficacy of combination therapy of diode laser and photodynamic therapy (PDT) as an adjunct to scaling and root planing (SRP) on interleukin-17 (IL-17) levels in gingival crevicular fluid (GCF) in patients with chronic periodontitis. Methods: Thirty subjects with chronic periodontitis were included. All teeth received periodontal treatment comprising of SRP. Using a split mouth study design, the test group was additionally treated with a combination therapy of diode laser and PDT. GCF was collected to evaluate IL-17 levels at baseline and 3 months. Results: There was no difference in baseline values for levels of IL-17 in GCF in the test group and the control group. A significant decrease in GCF levels of IL-17 was observed in both treatment groups 3 months after treatment (P < 0.001). However, the treatment groups showed no significant difference (P > 0.05). Conclusion: Based on the results of the present study it was co...