EFFECT OF DIODE LASER TREATMENT ON THE LEVEL OF IL-6 IN THE GINGIVAL CREVICULAR FLUID IN PATIENTS WITH CHRONIC PERIODONTITIS (original) (raw)

The aim of this trial was to determine the efficacy of Diode Laser Therapy (DLT) as an adjunct to scaling and root planing (SRP) in periodontal therapy on the basis of clinical measurements and level of IL-6 in gingival crevicular fluid (GCF). The study involved 40 patients with moderate chronic periodontitis, randomly assigned into two groups. The first group (test group) included 20 patients to whom the procedure SRP and additional application of DLT (808 nm) has been performed. The second group (control group) included 20 patients treated only by SRP procedure. In both groups the treatment has been applied in four visits twice a week. The clinical parameters of Hygiene index (HI), Bleeding on probing (BOP), Probing pocket depth (PPD), and Clinical attachment level (CAL) were measured at baseline and 1 month after treatment. Detection of IL-6 levels in GCF was conducted before treatment and four weeks after treatment completion. One month after treatment both groups showed significant improvements with regard to clinical parameters HI and BOP compared to baseline. The tendency of reduction in proinflammatory cytokine IL-6 level in GCF, recorded one month after treatment in the test group only, not in the control group showed the additional beneficial effects of DLT applied as an adjunct to SRP in the treatment of chronic periodontitis.