Histopathological Evaluation of Lesions of Appendix - A Cross Sectional Study (original) (raw)
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Histopathological Study of Lesions of the Appendix
https://www.ijhsr.org/IJHSR\_Vol.7\_Issue.4\_April2017/IJHSR\_Abstract.015.html, 2017
The human appendix is a supposedly functionless organ, but can cause morbidity & mortality because it is likely to become infected. A two years study was performed to determine the incidence of various non-neoplastic and neoplastic lesions of the appendix. In each case, clinical findings were correlated with histopathological features. Out of 436 appendicectomy specimens, 99.34% were involved by non-neoplastic lesions and 0.66 % by neoplastic lesions. Non-neoplastic lesions included acute appendicitis with/without perforation, chronic appendicitis, worm infestation and fibrous obliteration. Neoplastic lesions included 1 case each of neuroendocrine neoplasm (NET), adenoma & Non-Hodgkin lymphoma.
A Histopathological Study of the Appendix after Surgical Resection
Scholars Journal of Applied Medical Sciences, 2021
Original Research Article Introduction: Acute appendicitis is one of the most common causes of acute abdomen that demands emergency surgery. It is a clinical condition with an ongoing diagnostic challenge. Sometimes grossly normal-appearing appendix, removed from patients with suspected acute appendicitis, on histopathological examination may reveal a more serious underlying pathology. Hence, histopathological studies form the gold standard for diagnosis of acute appendicitis. Faecoliths are the usual cause of obstruction, though there are many other causes, ranging from inflammatory conditions to malignancies. Aim: To study histopathological patterns of appendicitis in all the patients who underwent appendicectomy at our institution to correlate with the clinical diagnosis. Materials and Method: This is a study of 460 appendicectomies carried out at Sylhet Women's Medical College and Hospital during a period of 1year from August 2017 to July 2018. Clinical data was collected from patients and corresponding appendicectomy specimens were submitted to histopathology department of Sylhet Women's Medical College and were processed routinely. Sections obtained were studied to determine various histopathological patterns in appendicectomy specimens. Results: A total of 460 specimens were analyzed. 276(60%) were females and 184(40%) were males. The histopathological examination showed acute appendicitis (69.18%), chronic appendicitis (8.48%), acute suppurative appendicitis (8.07%), eosinophilic appendicitis (2.83%), and carcinoid tumor (1.08%), and parasitic infestation (1.40%), mucocele of appendix (0.8%). Negative appendiectomy rate was found to be (8.70%). Conclusion: Appendicities has a peak incidence in second and third decade of life. Most of the cases in this study were diagnosed with usual features of appendicitis, though a few of them were essential incidental diagnoses which were missed preoperatively or intraoperatively. These important incidental diagnoses undeniably support the importance of routine histopathological examination of all appendectomy specimens after appendectomy.
National Journal of Laboratory Medicine, 2019
Introduction: Acute appendicitis is the most common abdominal emergency and has remained an on going diagnostic challenge. Histopathologic studies are the gold standard for final diagnosis. Aim: To study the histopathological features of appendix and utility of Ultrasonography (USG) in diagnosis of appendicitis. Materials and Methods: A two-year retrospective study from 1st January 2016 to 31st December 2017 of 472 appendectomy cases. Demography, clinical findings, radiologic and laboratory studies, histopathology findings were analysed. Results: Among the 472 appendectomy cases 283 (59.95%) were males and 189 (40.04%) were female patients. Most of the patients presented in the 3rd decade. Mean age was 29.25± 15.09 years (median age-26). Most common histopathological finding was Acute Appendicitis with Perforation comprising of 187 cases (39.61%) followed by acute appendicitis comprising of 117 cases (24.78%). Unusual findings were tubercular appendicitis. Most common neoplasm was L...
Routine Histopathological Examination of Appendix: The Practice That Cannot Be Ignored
https://www.ijhsr.org/IJHSR\_Vol.11\_Issue.4\_April2021/IJHSR-Abstract.06.html, 2021
Background: Acute appendicitis is a global disease that is usually caused by luminal obstruction with fecoliths. Aim: The aim of this study is to estimate the incidence of unusual findings in appendectomy specimens that can affect patient's morbidity and mortality. Methods and Material: This is a retrospective study of 340 appendectomies that were preformed from January 2018 to December 2019 at King Hamad University Hospital (KHUH). Histopathological reports were reviewed and final diagnosis, age and gender were recorded. Results: Of the 340 appendectomy specimens, acute appendicitis was the most prevalent finding 62.64% (and showed significant correlation with both genders P value <0.001). Unusual findings were seen in (8.49%) cases and the commonest unexpected finding was fibrous obliteration (4.11%) followed by carcinoid (1.76%). Conclusions: this study revealed that although majority of appendicectomy cases fall in the spectrum of inflammatory cases with low incidence of unusual findings, it is atmost importance to perform the histopathological examination as it still change the course of treatment and affect the overall prognosis of the patients.
Journal of the National Medical Association, 2000
An audit of 3374 appendectomy specimens in 2578 Saudi and 796 non-Saudi nationals revealed a diagnosis rate of 74.7% of inflamed appendix, a normal appendix range of 7.8% to 22.5% with the higher rate of normal appendix found among females. The finding of high incidence of schistosomal appendicitis among Egyptian males is not surprising given the high incidence of schistosomiasis among Egyptians in general. The alternate diagnoses, which include such conditions as neoplasm, mucocele, other inflammatory conditions such as periappendicitis, and parasitic infestations, are not different from findings in the reported literature.
International journal of current research and review, 2021
Introduction: Appendicitis is the most common pathological condition of the appendix. Appendectomy is a surgical procedure to remove the appendix constituting 40% of all abdominal surgeries performed in the world. Objective: The present study was conducted to analyze the histopathological profile of surgically resected appendix and create a clinical profile that may help in better diagnosis and management of appendicitis. Methods: Histopathological records of 616 resected specimens of the appendix were reviewed retrospectively to correlate clinical profile, histopathologic findings and unusual findings. Results: The study included 616 specimens of appendix out of which 371(60.22%) specimens were of males and 245(39.77%) specimens were of females. The most commonly affected age group was of 21 to 30 years with 285(45.96%) samples. On histopathological examination, 95 (15.3%) samples were of acute appendicitis. 314 (50.6%) samples were of chronic appendicitis, 155 samples (25%) had an...
Histopathological spectrum of appendicectomy specimens -A prospective study
IP Innovative Publication Pvt. Ltd., 2017
Introduction: Acute appendicitis accounts for one of the most common conditions that demands emergency surgery. It is a clinical entity with an ongoing diagnostic challenge. Grossly, normal-appearing appendix, removed from patients with suspected acute appendicitis, on histopathological examination may reveal a more serious underlying pathology. Hence, histopathological studies form the gold standard for diagnosis of acute appendicitis. Faecoliths are the usual cause of obstruction, though there are many other causes, ranging from inflammatory conditions to malignancies. Aim: To study histopathological patterns in all the patients who underwent appendectomy at our institution for a duration of 18 months, and to correlate with the clinical diagnosis. Materials and Method: This is a prospective study of 230 appendicectomies carried out at Dr. B.R. Ambedkar Medical College and Hospital during a period of 18 months from April 2015 to October 2016. Clinical data was collected from patients of corresponding appendicectomy specimens received in histopathology department of Dr. B.R. Ambedkar Medical College and were processed routinely. Sections obtained were studied to determine various histopathological patterns in appendicectomy specimens. Results: A total of 230 specimens were analyzed. 139(60.4%) were males and 91(39.6%) were females. The histopathological examination showed Acute appendicitis (46.5%), Chronic/recurrent appendicitis (27.8%), Acute suppurative appendicitis (6.5%), Eosinophilic appendicitis (3.5%), Gangrenous appendicitis (2.2%), Perforated appendicitis (1.3%), Carcinoid tumor (1.3%), Parasitic infestation (1.3%), Mucinous cystadenoma (0.4%). Negative appendiectomy rate was found to be 9.2%. Conclusion: Most of the cases in this study were diagnosed with usual features of appendicitis, though a few of them were essential incidental diagnoses which were missed preoperatively or intraoperatively. These important incidental diagnoses undeniably support the notion that all appendectomy specimens should be sent routinely for histopathological examination, which is not followed in many hospitals in India.
Histopathologic analysis of appendectomy specimens
Journal of Pathology of Nepal, 2012
Background: Acute appendicitis is one of the common conditions requiring emergency surgery. A retrospective study was performed to determine various histopathological diagnoses, their demographics and the rates of perforated appendicitis, negative appendectomy and incidental appendectomy. Materials and Methods: Histopathological records of resected appendices submitted to histopathology department Chitwan medical college teaching hospital over the period of 2 yrs from May, 2009 to April 2011 were reviewed retrospectively. Results: Out of 930 specimens of appendix, appendicitis accounted for 88.8% with peak age incidence in the age group of 11 to 30 yrs in both sexes. Histopathologic diagnoses included acute appendicitis (45.6%), acute suppurative (20.8%), gangrenous (16.3%), perforated (1.7%), resolving /recurrent/non specific chronic appendicitis (2.5%), acute eosinophilic appendicitis (1.2%), periappendicitis (0.2%), and carcinoid tumour (0.1%). Other important coexisting patholog...