Study of Oral Versus Intravenous Iron Therapy in Postpartum Anaemic Women (original) (raw)
2017, Journal of Evolution of Medical and Dental Sciences
BACKGROUND Anaemia is a serious nutrition problem affecting millions in developing countries and remains a major challenge for human health and social and economic development. Iron deficiency is thought to be the most common cause of anaemia globally. MATERIALS AND METHODS It was a prospective randomised controlled trial, single centric study involving women with postpartum IDA. Improvements of those who were treated with injectable iron were compared with those who were treated with oral iron. RESULTS The demographic variables like age, BMI, habitat, dietary habits, parity, antenatal presence of anaemia, modes of delivery and type of risk factors were comparable. In oral iron therapy group, mean Hb on Day 0 was 8.008 ± 0.5435 gm/dL. On 2 nd week mean Hb rises to 8.924 ± 0.7660 gm/dL and on 6 th week mean Hb rises to 9.889 ± 0.9467 gm/dL. In injectable iron therapy group mean Hb on Day 0 was 7.822 ± 0.5422 gm/dL, in the 2 nd week mean rise in Hb was 10.362 ± 0.9354 gm/dL and in 6 th week Hb rise was 12.858 ± 0.6616 gm/dL. CONCLUSION Intravenous iron therapy administration increases the haemoglobin level and iron store more rapidly than oral iron intake in women with iron deficiency anaemia in the postnatal period. It can be used as safe and effective alternative to blood transfusion and oral iron therapy in the treatment of iron deficiency anaemia in the postpartum period. If cost is not a limiting factor, limited dosage schedule of iron sucrose as prescribed in the study is a safe and effective alternative to daily oral iron taken in treatment of postpartum anaemia. Multiple child birth, poor socioeconomic status, dietary habits, type of habitat and education status of mother also contributed to the incidence of postpartum anaemia.
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