P0098 Approach to an Acute Pancreatitis Complicated with Giant Pseudocyst (original) (raw)

Background: Nonalcoholic fatty liver disease (NAFLD) shares similar risk factors with coronary artery (CAD). NAFLD is getting more common and present in up to one-third of the Turkish population while Turkish people change their traditional lifestyle nutrutinal behaviors. We aimed to determine if NAFLD has any role in the development of CAD. The other question was the need of screening or surveillance of NAFLD patients for CAD in Turkey. Method: We evaluated the risk factors for CAD and demografic characteristics of NAFLD patients. 34 patients diagnosed with NAFLD by ultrasonography and alcohol cosumption history were enrolled. Demographic and anthropometric parameters, oral glucose tolerance test with insulin levels, transaminase levels, C-reactive protein (CRP) and all components of metabolic syndrome criteria were measured in all patients. The patients were evaluated for CAD by a cardiologist according to guidelines. Results: Elevated transaminase level was found in 37% of NAFLD patients. This increase was significantly associated with body mass index, waist/hip ratio, fasting glucose, hyperinsulinemia, low high density lipoprotein (HDL), male sex, high CRP levels. CAD was found in 32.6% of patients with elevated transaminase and only 10.2% of patients with normal transaminase. Conclusion: These findings strongly suggest that NAFLD is likely to be associated with increased CAD risk. Screening and surveillance stratagies for CAD may be suggested to patients with NAFLD especially when they have elevated transaminases (steatohepatitis) in Turkey.