Fabrication and Microstructure Evaluation of Fibrous Composite for Acetabular Labrum Implant (original) (raw)
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Materials, 2019
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Biomaterials, 2005
Poly(e-caprolactone) (PCL)/continuous bioglass fibre composite was prepared using the monomer transfer moulding technique coupled with a surface initiated polymerisation. The bioglass fibres were surface treated with an amine ended silane in order to initiate polymerisation of e-caprolactone from the fibre surface. Surface initiated polymerisation significantly improved the Young's modulus and flexural strength and water resistance of the composite. Initial in vitro biocompatibility assessment suggests that amine ended silane treatment of bioglass fibres before their inclusion in the composite does not have a negative effect on the biological responses in terms of macrophage activation as measured by IL-1b release and craniofacial osteoblast attachment. r
Nanomaterials
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Applied Sciences
Polycaprolactone (PCL) is one of the most used synthetic polymers for medical applications due to its biocompatibility and slow biodegradation character. Combining the inherent properties of the PCL matrix with the characteristic of nanofibrous particles, result into promising materials that can be suitable for different applications, including the biomedical applications. The advantages of nanofibrous structures include large surface area, a small diameter of pores and a high porosity, which make them of great interest in different applications. Electrospinning, as technique, has been heavily used for the preparation of nano- and micro-sized fibers. This review discusses the different methods for the electrospinning of PCL and its composites for advanced applications. Furthermore, the steady state conditions as well as the effect of the electrospinning parameters on the resultant morphology of the electrospun fiber are also reported.
Wear characteristic and biocompatibility of some polymer composite acetabular cups
Wear, 2004
Both HDPE and UHMWPE have long been used successfully as socket materials in hip-joint replacements. Recently, however there are concerns over the adverse biological responses due to the wear debris of these polymers. Although a good deal of work to improve the performance of these polymers has been carried out a need still exists for an implant material with improved biocompatibility and mechanical properties. Hydroxyapatite-collagen composites have been prepared by precipitation of calcium phosphate on collagen in the past but very few of these attempts considered the mechanical strength of the composites that suits their realistic uses as implant material. Present work is an attempt to develop hybrid composites of hydroxyapatite-collagen-hyaluronic acid or gelatin with sufficient adherence to both hard and soft tissues and also with good cohesive strength leading to improved mechanical and biological properties. It was possible to prepare acetabular cups of the newly developed composites by compression moulding for tests on a hip-joint simulator. Pin specimens for tests on a pin-on-disc apparatus were also moulded with these composites. Tests with the acetabular cups and pin specimens indicate that some of the newly developed materials offer wear resistance comparable to those of the presently used socket materials. Biocompatibility tests with these materials show that their haemolysis counts are well below the acceptable range. Hydroxyapatite-collagen composites with 10% hyaluronic acid offer suitable mechanical strengths, good friction and wear characteristics and acceptable level of haemolysis and therefore the composite may be considered to be a potential socket material of future generation.
European journal of oral sciences, 2014
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Journal of the mechanical behavior of biomedical materials, 2015
Fully bioresorbable composites have been investigated in order to replace metal implant plates used for hard tissue repair. Retention of the composite mechanical properties within a physiological environment has been shown to be significantly affected due to loss of the integrity of the fibre/matrix interface. This study investigated phosphate based glass fibre (PGF) reinforced polycaprolactone (PCL) composites with 20%, 35% and 50% fibre volume fractions (Vf) manufactured via an in-situ polymerisation (ISP) process and a conventional laminate stacking (LS) followed by compression moulding. Reinforcing efficiency between the LS and ISP manufacturing process was compared, and the ISP composites revealed significant improvements in mechanical properties when compared to LS composites. The degradation profiles and mechanical properties were monitored in phosphate buffered saline (PBS) at 37°C for 28 days. ISP composites revealed significantly less media uptake and mass loss (p<0.001...
Design of a polymeric composite material femoral stem for hip joint implant
Polímeros, 2019
Hip joint prosthesis are structural components that still have some challenging problems such as the interaction of physical and biological properties between the stem and the human femur. Composite materials allow to obtain high strength structures with a large variety of modulus of elasticity and favorable characteristics in the context of orthopedic implants. Therefore, the objective of this work was the development of a prosthesis model with biopolymeric matrix, namely the polyurethane (PU) derived from castor oil, reinforced with fiberglass. The implants were made of pure PU, PU with fiberglass, and PU with glass fiber and calcium carbonate. The reinforcement was constructed in the form of a core to be inserted into the hip prosthesis. The core and stem prototypes were produced using three-dimensional printing techniques, and subsequently used in the manufacture of flexible silicone molds. The results showed good mechanical potentialities of this material for orthopedics applications.
Materials Chemistry and Physics, 2009
Biodegradable polymeric nanofibrous coatings were obtained by electrospinning different polymers onto sintered 45S5 Bioglass ® -based glass-ceramic pellets. The investigated polymers were poly(3hydroxybutyrate) (P3HB), poly(3-hydroxybutyrate-co-hydroxyvalerate) (PHBV) and a composite of poly(caprolactone) (PCL) and poly(ethylene oxide) (PEO) (PCL-PEO). The fibrous coatings morphology was evaluated by optical microscopy and scanning electron microscopy. The electrospinning process parameters were optimised to obtain reproducible coatings formed by a thin web of polymer nanofibres. In-vitro studies in simulated body fluid (SBF) were performed to investigate the bioactivity and mineralisation of the substrates by inducing the formation of hydroxyapatite (HA) on the nanofiber-coated pellets. HA crystals were detected on all samples after 7 days of immersion in SBF, however the morphology of the HA layer depended on the characteristic fibre diameter, which in turn was a function of the specific polymer-solvent system used. The bioactive and resorbable nanofibrous coatings can be used to tailor the surface topography of bioactive glass-ceramics for applications in tissue engineering scaffolds.