Molecular profiling in glioblastoma: Prelude to personalized treatment (original) (raw)

Clinical Significance of Molecular Biomarkers in Glioblastoma

Petr Kavan

The Canadian Journal of Neurological Sciences, 2010

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Molecular Analysis in a Glioblastoma Cohort—Results of a Prospective Analysis

tonia cenci

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Diagnostic and Therapeutic Biomarkers in Glioblastoma: Current Status and Future Perspectives

Gabriela kramer-MareK

BioMed Research International, 2017

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Multi-platform molecular profiling of a large cohort of glioblastomas reveals potential therapeutic strategies

Santosh Kesari

Oncotarget, 2016

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The combined EGFR protein expression analysis refines the prognostic value of the MGMT promoter methylation status in glioblastoma

Valerio Nardone

Clinical Neurology and Neurosurgery, 2016

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MGMT Methylation Status: The Advent of Stratified Therapy in Glioblastoma?

Peter Hau

Disease Markers, 2007

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Molecular diagnostics of gliomas: the clinical perspective

Martin Van Den Bent

Acta Neuropathologica, 2010

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Protein Markers Predict Survival in Glioma Patients

Jean-Eudes Dazard

Molecular & Cellular Proteomics, 2016

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MGMT promoter methylation in malignant gliomas: ready for personalized medicine?

Martin Van Den Bent

Nature Reviews Neurology, 2009

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A practical review of prognostic correlations of molecular biomarkers in glioblastoma

Jayson Neil

Neurosurgical Focus, 2015

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MGMT and Whole-Genome DNA Methylation Impacts on Diagnosis, Prognosis and Therapy of Glioblastoma Multiforme

Rosa Della Monica

International Journal of Molecular Sciences

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MGMT methylation analysis of glioblastoma on the Infinium methylation BeadChip identifies two distinct CpG regions associated with gene silencing and outcome, yielding a prediction model for comparisons across datasets, tumor grades, and CIMP-status

Martin Van Den Bent

Acta Neuropathologica, 2012

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Activation of PI3K/mTOR pathway occurs in most adult low-grade gliomas and predicts patient survival

Daphne Haas-kogan, David Stokoe

Journal of Neuro-Oncology, 2010

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High incidence of MGMT and RARbeta promoter methylation in primary glioblastomas: association with histopathological characteristics, inflammatory mediators and clinical outcome

George Papavassiliou, Christos Adamopoulos, Christina Piperi

Molecular medicine (Cambridge, Mass.)

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MGMT Promoter Methylation as a Prognostic Factor in Primary Glioblastoma: A Single-Institution Observational Study

Paulina Śledzińska

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Prospective, high-throughput molecular profiling of human gliomas

Leif Ellisen

Journal of Neuro-Oncology, 2012

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Recent advances in the molecular understanding of glioblastoma

Sieger Leenstra

Journal of Neuro-Oncology, 2012

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Concordant association validates MGMT methylation and protein expression as favorable prognostic factors in glioma patients on alkylating chemotherapy (Temozolomide)

Dheera Sanadhya

Scientific Reports, 2018

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Prognostic Molecular and Imaging Biomarkers in Primary Glioblastoma

Edit Bosnyák

Clinical nuclear medicine, 2017

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Differential Regulation of the EGFR/PI3K/AKT/PTEN Pathway between Low- and High-Grade Gliomas

ALVEIRO ERIRA

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Genomic and Epigenomic Features of Glioblastoma Multiforme and its Biomarkers

Muhammad Ghazi Abbas

Journal of Oncology

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Prognostic Impact of MGMT Promoter Methylation in Glioblastoma - A Systematic Review

Luigi Maria Larocca

Journal of Cancer Science & Therapy, 2014

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Role of MGMT Methylation Status at Time of Diagnosis and Recurrence for Patients with Glioblastoma: Clinical Implications

Enrico Franceschi

The Oncologist, 2017

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Role of MGMT Methylation Status at Time of Diagnosis and Recurrence for Patients with Glioblastoma: Clinical Implications

Giovanni Lanza

Oncologist, 2017

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Subtype-specific signaling pathways and genomic aberrations associated with prognosis of glioblastoma

Pora Kim

Neuro-Oncology

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MGMT promoter methylation in malignant gliomas

Martin Van Den Bent

Targeted Oncology, 2010

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Influence of Intratumor Heterogeneity on the Predictivity of MGMT Gene Promoter Methylation Status in Glioblastoma

Lorena Gurrieri

Frontiers in Oncology, 2020

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