Metabolism of Xenobiotics during Percutaneous Penetration: Role of Absorption Rate and Cutaneous Enzyme Activity
Jan Storm
Toxicological Sciences, 1990
View PDFchevron_right
A protocol to determine dermal absorption of xenobiotica through human skin in vitro
Robert Landsiedel
Archives of Toxicology, 2016
View PDFchevron_right
Extent of cutaneous metabolism during percutaneous absorption of xenobiotics
Jan Storm
Toxicology and Applied Pharmacology, 1989
View PDFchevron_right
The in vivo dermal absorption and metabolism of [4-14C]coumarin by rats and by human volunteers under simulated conditions of use in fragrances
Anne Api
Food and Chemical Toxicology, 2001
View PDFchevron_right
A Comparison of the Absorption of a Series of Ethoxylates through Rat Skin In Vitro
Peter Blain
Toxicology in Vitro, 1998
View PDFchevron_right
Xenobiotica-metabolizing enzymes in the skin of rat, mouse, pig, guinea pig, man, and in human skin models
Robert Landsiedel
Archives of toxicology, 2018
View PDFchevron_right
Xenobiotic-metabolizing enzymes in the skin of rat, mouse, pig, guinea pig, man, and in human skin models
Robert Landsiedel
Archives of toxicology, 2014
View PDFchevron_right
Development of In Vitro Isolated Perfused Porcine Skin Flaps for Study of Percutaneous Absorption of Xenobiotics
Nancy A Monteiro-Riviere
View PDFchevron_right
Dermal xenobiotic metabolism: a comparison between native human skin, four in vitro skin test systems and a liver system
Nicola Hewitt
Skin pharmacology and physiology, 2014
View PDFchevron_right
Dermal metabolism of topically applied drugs: Pathways and models reconsidered
Hans P Merkle
Pharmaceutica Acta Helvetiae, 1995
View PDFchevron_right
Physical model approach to understanding finite dose transport and uptake of hydrocortisone in hairless guinea-pig skin
Adam Ghanem
International Journal of Pharmaceutics, 1992
View PDFchevron_right
Xenobiotic metabolism capacities of human skin in comparison with a 3D-epidermis model and keratinocyte-based cell culture as in vitro alternatives for chemical testing: phase II enzymes
Julia Tigges
Experimental dermatology, 2012
View PDFchevron_right
Skin metabolism of topically applied compounds
Jonathan Hadgraft, S. Denyer
International Journal of Pharmaceutics, 1987
View PDFchevron_right
Phase II Metabolism in Human Skin: Skin Explants Show Full Coverage for Glucuronidation, Sulfation, N-Acetylation, Catechol Methylation, and Glutathione Conjugation
Dirk Schaefer
Drug Metabolism and Disposition, 2014
View PDFchevron_right
Comparison of the metabolism of 10 chemicals in human and pig skin explants
Nicola Hewitt
Journal of Applied Toxicology, 2018
View PDFchevron_right
Coumarin derivatives, but not coumarin itself, cause skin irritation via topical delivery
Jia-you Fang
Toxicology Letters, 2014
View PDFchevron_right
An automated in vitro dermal absorption procedure: III. In vivo and in vitro comparison with the insect repellent N,N-diethyl-m-toluamide in mouse, rat, guinea pig, pig, human and tissue-cultured skin
Len Ritter
Toxicology in Vitro, 1993
View PDFchevron_right
Xenobiotic metabolism capacities of human skin in comparison with a 3D epidermis model and keratinocyte-based cell culture as in vitro alternatives for chemical testing: activating enzymes (Phase I)
Julia Tigges, Christine Jäckh
Experimental Dermatology, 2012
View PDFchevron_right
Partition coefficient and diffusion coefficient determinations of 50 compounds in human intact skin, isolated skin layers and isolated stratum corneum lipids
Nicola Hewitt
Toxicology in Vitro, 2020
View PDFchevron_right
Comparative in Vitro-in Vivo Percutaneous Absorption of the Pesticide Propoxur
Nicole H.p Cnubben, Johannes Sandt
Toxicological Sciences, 2000
View PDFchevron_right
The Use of Mechanistically Defined Chemical Mixtures (MDCM) to Assess Mixture Component Effects on the Percutaneous Absorption and Cutaneous Disposition of Topically Exposed Chemicals II. Development of a General Dermatopharmacokinetic Model for Use in Risk Assessment
Nancy A Monteiro-Riviere
Toxicology and Applied Pharmacology, 1996
View PDFchevron_right
In vitro dermal toxicology using skin organ cultures
Johannes Sandt
Toxicology in Vitro, 1994
View PDFchevron_right
The Dermal Absorption of Selected Agricultural and Industrial Chemicals Through Porcine Skin with Emphasis on Chemical Mixture Effects
Deon Van der Merwe
2005
View PDFchevron_right
Reconstructed epidermis versus human and animal skin in skin absorption studies
Ahmed Mahmoud, Helena Kandárová, Dr.rer.nat, Ing., ERT
Toxicology in Vitro, 2005
View PDFchevron_right
Label-Free Quantitative Proteomics and Substrate-Based Mass Spectrometry Imaging of Xenobiotic Metabolizing Enzymes in Ex Vivo Human Skin and a Human Living Skin Equivalent Model
Narciso Couto
Drug Metabolism and Disposition
View PDFchevron_right
Irradiation of Skin and Contrasting Effects on Absorption of Hydrophilic and Lipophilic Compounds
laurent blasco
Photochemistry and Photobiology, 2009
View PDFchevron_right