MCUR1, CCDC90A, Is a Regulator of the Mitochondrial Calcium Uniporter (original) (raw)
MCUR1 is an Essential Component of Mitochondrial Ca2+ Uptake that regulates Cellular Metabolism
cesar cardenas
Biophysical Journal, 2013
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The mitochondrial calcium uniporter (MCU): molecular identity and physiological roles
Diego De Stefani
The Journal of biological chemistry, 2013
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The mitochondrial calcium uniporter complex: molecular components, structure and physiopathological implications
Paolo Pinton
The Journal of Physiology, 2014
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Mitochondrial Ca2+ uniporter (MCU)-dependent and MCU-independent Ca2+ channels coexist in the inner mitochondrial membrane
Roland Malli
Pflügers Archiv - European Journal of Physiology, 2013
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MICU1 and MICU2 Finely Tune the Mitochondrial Ca(2+) Uniporter by Exerting Opposite Effects on MCU Activity
Diego De Stefani
Molecular cell, 2014
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MICU1 is an Essential Gatekeeper for MCU-Mediated Mitochondrial Ca2+ Uptake that Regulates Cell Survival
cesar cardenas
Biophysical Journal, 2013
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The Function of Mitochondrial Calcium Uniporter at the Whole-Cell and Single Mitochondrion Levels in WT, MICU1 KO, and MICU2 KO Cells
Ghanim Ullah
Cells, 2020
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Structure and function of the mitochondrial calcium uniporter complex
Maria Patron
Biochimica et biophysica acta, 2015
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Mitochondrial Ca(2+) Uniporter Is a Mitochondrial Luminal Redox Sensor that Augments MCU Channel Activity
Edmund Carvalho
Molecular cell, 2017
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MICU2, a Paralog of MICU1, Resides within the Mitochondrial Uniporter Complex to Regulate Calcium Handling
Yasemin Sancak, Lauren Speciner, Jack De Groot
PLoS ONE, 2013
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MCUB and mitochondrial calcium uptake – modeling, function, and therapeutic potential
Emma K. Murray
Expert Opinion on Therapeutic Targets
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MICU1 Controls Both the Threshold and Cooperative Activation of the Mitochondrial Ca2+ Uniporter
David Weaver
Cell Metabolism, 2013
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SLC25A23 augments mitochondrial Ca2+ uptake, interacts with MCU, and induces oxidative stress-mediated cell death
Joseph Cheung
Molecular Biology of the Cell, 2014
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A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter
Enrico Teardo
Nature, 2011
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MICU1 Motifs Define Mitochondrial Calcium Uniporter Binding and Activity
Joseph Cheung
Cell Reports, 2013
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Mechanisms of EMRE-Dependent MCU Opening in the Mitochondrial Calcium Uniporter Complex
Enrique Balderas
Cell Reports, 2020
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MICU1 encodes a mitochondrial EF hand protein required for Ca2+ uptake
Vishal Gohil
Nature, 2010
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The mitochondrial Ca2+ uniporter: Regulation by auxiliary subunits and signal transduction pathways
Shey-shing Sheu
American journal of physiology. Cell physiology, 2016
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Activity of the mitochondrial calcium uniporter varies greatly between tissues
francesca fieni
Nature Communications, 2012
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Mitochondrial Ca2+ uniporter (MCU) variants form plasma-membrane channels
Iuliia Polina
bioRxiv (Cold Spring Harbor Laboratory), 2023
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Deletion of mitochondrial calcium uniporter incompletely inhibits calcium uptake and induction of the permeability transition pore in brain mitochondria
Jacob Rysted
The Journal of biological chemistry, 2018
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UCP2 modulates single-channel properties of a MCU-dependent Ca2+ inward current in mitochondria
Alexander Bondarenko
Pflügers Archiv - European Journal of Physiology, 2015
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Structure and mechanism of the mitochondrial Ca2+ uniporter holocomplex
Minrui Fan
Nature, 2020
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Leucine Zipper EF Hand-containing Transmembrane Protein 1 (Letm1) and Uncoupling Proteins 2 and 3 (UCP2/3) Contribute to Two Distinct Mitochondrial Ca2+ Uptake Pathways
Alexander Bondarenko
Journal of Biological Chemistry, 2011
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