COVID-19 Pandemic: Both a Blessing and Curse (original) (raw)
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COVID19 - A Daredevil or A Blessing In Disguise
Journal of Bahria University Medical and Dental College, 2021
COVID19 starting as an epidemic last year (2019) from Wuhan, China got converted into a pandemic within months with its devastating ravages throughout the world. The pandemic and its spread with its severity affected both poor and rich countries equally, which had a larger population. The measures taken by China, though, were initially challenged and even termed against the ‘human rights’ for the complete lockdown but soon were adopted by many countries.
A focus on CORONA VIRUS (COVID-19)
International Journal of Research in Pharmaceutical Sciences, 2020
The coronavirus episode is a worldwide concern. As time passes, the circumstance appears to change for the most noticeably terrible. An ever-increasing number of individuals are af irmed as contaminated, the death rate goes up somewhat with each deadly case and the infection is advancing outside the Chinese outskirts. The news outlets are everywhere throughout the point, giving day by day or even hourly updates to the inexorably critical circumstance. Be that as it may, most articles and reports appear to concentrate more on instigating alarm and making disarray as opposed to giving an account of logical realities or advancing avoidance measures Along these lines, for this article, how about we leave the frenzy aside and see where that brings us. The Wuhan infection is the main signi icant wellbeing danger of 2020, yet it's a long way from being the irst or the most noticeably awful wellbeing emergency that humankind confronted. Before we had the Ebola infection, Avian lu and SARS, with the keep goisecng on this rundown, really being a kind of coronavirus. All were profoundly infectious and possibly savage, yet none caused such an instinctive response from the populace. Regardless of whether we dismiss those, we have the basic in luenza infection that causes a large number of passing right off the bat, and we don't hear much about that in the news, isn't that right?
One month of the novel coronavirus 2019 outbreak: Is it still a threat?
VirusDisease, 2020
The novel coronavirus 2019 disease (COVID-19) is now in an outbreak not only in China but also around the world, suspected to be originated from a wet market in Wuhan, Hubei province, China. The flare-up of COVID-19, it has already been infected 78,811 people with 2462 fatalities in 1 month window. The most alarming issue is the virus can transmit from host to host and still asymptomatic. Currently, 24 counties with 505 confirmed cases have been reported. Presently, there is no specific treatment or vaccine but physicians are battling with the use of antibiotics, steroid, anti-viral and anti-HIV drugs and some of the infected cases are testified improved. WHO and China National health Commission are cooperatively striving to come up with elucidation but it will take a minimum of 3 to 4 months at least to undergo a phase-1 trial. However, the soaring rates of spreading each day has become much stable which might even improve within the next few weeks in China but not for some other countries. Healthy peoples are instructed to avoid public gathering, always wearing the mask and frequently wash hands. Currently, China has able to hold up more than 97.7% infection within China but a scientific breakthrough is crucial before it’s too late.
Academic Publication , 2020
The new coronavirus (SARS-CoV-2) pneumonia that occurred in Wuhan, China in December 2019 is a highly contagious disease. The World Health Organization (WHO) has declared the current outbreak of a global public health emergency. It was originally called the 2019 Novel Coronavirus (2019-nCoV) and was recently reclassified as Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). The disease it causes is called Coronavirus Disease 2019 (COVID-19). First observed in Wuhan, China, it is now rapidly spreading throughout the world. As of April 15, 2020, 2,034,913 confirmed cases have been confirmed worldwide, with 129,913 deaths. The World Health Organization (WHO) called COVID-19 a pandemic on March 11, 2020. However, vaccines are not available, so the best way to fight the virus is prophylactic.
THE SPREAD OF THE NEW CORONAVIRUS
2020
The spread of COVID-19 continues in China and in the world as the World Health Organization (WHO) baptized it, warned since 31-12-2019 of the new SARS (Severe Acute Respiratory Syndrome). The epidemic has its own basic reproduction number, Ro, which is considered less than 1 when it runs out of passage from one individual to another and tends to rise as in the previous SARS epidemic (2002-2003) between 2 and 4 to get to measles with values of 12-18. The current Ro is estimated between 2 and 3. More than 86 thousand are infected today 03-3-2020, with almost 3 thousand deaths. Flights to China have been suspended, while seasonal flu has infected and killed more people.
Coronavirus Disease (COVID-19) Pandemic: Scenario of Myths and Facts
Annals of Community Health, 2021
The COVID-19 pandemic started off in China in December 2019, which was declared as Public Health Emergency of International Concern (PHEIC) by the World Health Organization (WHO) on January 30, 2020, and later, it was declared as pandemic on March 11, 2020. [4-7] The first case of COVID-19 in India was reported on January 30, 2020. [4] Coronaviruses are enveloped non-segmented positive-sense RNA viruses which belong to the family Coronaviridae and the order Nidovirales and mainly distributed in humans and other mammals. While, most human coronavirus infections are mild, the epidemics of two betacoronaviruses, severe
Coronavirus Disease (COVID-19) Pandemic: A Race Against Time
Current Topics in Medicinal Chemistry, 2020
The emergence of a novel coronavirus, 2019-nCoV in Wuhan, Hubei province of China, at the end of 2019 and its rapid spread across the world has been alarming. This is the third outbreak of coronaviruses in the recent past after the SARS-CoV outbreak in 2002 and MERS-CoV in 2012. SARS-CoV2, a zoonotic virus that has originated in bats and jumped species from animals to infect humans, spreads mainly through human to human transmission from respiratory droplets on sneezing or coughing. This virus was named 2019-nCoV and the disease caused by it is referred to as COVID-19. The current 2019-nCoV outbreak was declared a Public Health Emergency of International Concern by WHO on 30 th January 2020. The gravity of the situation can be gauged by the fact that the number of cases has soared to 179112 cases and 7426 deaths and it has spread to 170 countries and territories claiming 8,272 lives [1]. WHO has declared the current outbreak of Coronavirus as pandemic on March 11, 2020. This is the first pandemic caused by a Coronavirus, and it has forced public health experts and policymakers to swing in action to control the situation. Symptoms include fever, dry cough, fatigue, pains, nasal congestion, runny nose, sore throat, shortness of breath, and breathing difficulties. In severe cases, the infection may lead to complications like pneumonia, severe acute respiratory syndrome, kidney failure and sometimes death. The virus has an incubation period of 1-14 days with many symptoms overlapping with the common cold and similar diseases. A recent study revealed the gender bias in COVID-19 as mortality and vulnerability were found to be higher in men compared to women [2]. 2019-nCoV(SARS-CoV2) is an enveloped, positive-sense, single-stranded RNA virus belonging to subgenus Sarbecovirus of the genus Betacoronavirus of Coronaviridae family. This genus also includes Severe Acute Respiratory Syndrome Coronavirus (SARSCoV) and Middle East Respiratory Syndrome coronavirus (MERS). Coronaviruses are spherical with club-shaped glycoprotein spikes or projections on their surface giving it a "corona" or halo-like appearance. Known to have one of the largest viral RNA genomes, the 2019-nCoV has a genome size of 29,891 bp with a GC content of 38% and codes for 9860 amino acids. It codes for 16 non-structural proteins, viz. chymotrypsin-like protease, papain-like protease, helicase, and RNA-dependent RNA polymerase(RdRp), and other non-structural proteins that play role in replication and transcription of the virus. The virus has four structural proteins, viz., spike surface glycoprotein, small envelope protein, matrix protein, nucleocapsid protein, and accessory proteins [3, 4]. Till 17.03.20, complete genomes of a total of 87 strains of the Severe Acute Respiratory Syndrome Coronavirus 2(SARS-CoV2) have been sequenced. Out of these, 48 strains have been isolated from the USA, 28 strains are from China, 2 each from India and Taiwan, and 1 each from Japan, Italy, Brazil, Australia, Sweden, Nepal, and South Korea. Entrez entry on 17.3.2020 suggests the availability of 93 nucleotide sequences, 496 protein sequences, 22 genes and also a complete genome sequence (NC_045512) from the sample of the epicenter Wuhan.
International Journal of Pathogen Research
The 2019 novel coronavirus (2019-nCov) has been implicated in the outbreak of an uncommon pneumonia in Chinese City of Wuhan, Hubei Province first reported in late December 2019. Since then, infection has spread to other Chinese cities, as well as internationally, threatening to trigger a pandemic. On January 30 2020, the World Health Organization (WHO) in an effort to slow down the global spread of the virus declared the outbreak, “A global public health emergency of international concern”. As at the time of this review, there were more than 31 000 confirmed cases and 638 deaths reported globally. Controversies exist on the origin of the virus with diverse views. The swift rise in morbidity and mortality rate of the virus has caused widespread alarm in China and other parts of the world. This review is aimed at providing relevant information on the possible origin of the virus, its mode of transmission, associated risk factors, existing controversies, consequences of the current tr...