Carb109M resistance phenotype when challenged with different Mexican DENV2 genotypes (original) (raw)
2014
Abstract
<p>HWE (control) and Carb109M (G<sub>9</sub>, G<sub>13</sub>, G<sub>14</sub>) mosquitoes were infected with DENV2 C-932/Acapulco 97, Mex96 Merida, QR94 Quintana Roo, and 14757 Yucatan, representing the Asian 2, Cosmopolitan, American, and Asian-American genotypes, respectively. Mosquitoes received DENV2-containing bloodmeals with the following titers: 1.3×10<sup>6</sup> pfu/ml (C-932/Acapulco 97), 2.0×10<sup>5</sup> pfu/ml (Mex96), 4.0×10<sup>6</sup> pfu/ml (QR94), and 2.0×10<sup>6</sup> (14757). Virus titers in the mosquitoes were assessed at 7 and 14 dpi. Each data point represents the virus titer of a single female. Mean values and standard errors are indicated.</p
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