Enterotoxin Adjuvants Have Direct Effects on T Cells and Antigen‐Presenting Cells That Result in Either Interleukin‐4–Dependent or –Independent Immune Responses (original) (raw)

Distinct Cytokine Regulation by Cholera Toxin and Type II Heat-Labile Toxins Involves Differential Regulation of CD40 Ligand on CD4+ T Cells

Michael Russell

Infection and Immunity, 2001

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Mucosal adjuvant effect of cholera toxin in mice results from induction of T helper 2 (Th2) cells and IL-4

Kohtaro Fujihashi

Journal of immunology (Baltimore, Md. : 1950), 1995

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Cholera Toxin andEscherichia coliHeat-Labile Enterotoxin, but Not Their Nontoxic Counterparts, Improve the Antigen-Presenting Cell Function of Human B Lymphocytes

Antonella Riccomi

Infection and Immunity, 2009

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Cholera Toxin and Escherichia coli Heat-Labile Enterotoxin, but Not Their Nontoxic Counterparts, Improve the Antigen-Presenting Cell Function of Human B Lymphocytes

Walter Patton

Infection and Immunity, 2009

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Comparative Analysis of the Mucosal Adjuvanticity of the Type II Heat-Labile Enterotoxins LT-IIa and LT-IIb

T. Connell

Infection and Immunity, 2000

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Differential Binding of Escherichia coli Enterotoxins LT-IIa and LT-IIb and of Cholera Toxin Elicits Differences in Apoptosis, Proliferation, and Activation of Lymphoid Cells

Michael Russell

Infection and Immunity, 2005

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Helper Th1 and Th2 cell responses following mucosal or systemic immunization with cholera toxin

Jerry McGhee

Vaccine, 1994

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Mechanisms for Mucosal Immunogenicity and Adjuvancy of Escherichia coli Labile Enterotoxin

Kohtaro Fujihashi

Journal of Infectious Diseases, 1996

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The type II heat-labile enterotoxins LT-IIa and LT-IIb and their respective B pentamers differentially induce and regulate cytokine production in human monocytic cells

T. Connell

2004

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Effects of cholera toxin on innate and adaptive immunity and its application as an immunomodulatory agent

Andrew Jarnicki

Journal of leukocyte biology, 2004

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Differential effect of cholera toxin on CD45RA+ and CD45RO+ T cells: specific inhibition of cytokine production but not proliferation of human naive T cells

Cecil Czerkinsky

Clinical and Experimental Immunology, 2000

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Cholera-Like Enterotoxins and Regulatory T cells

Christelle Basset

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Cholera Toxin (CT), Thermolabile Enterotoxin of E. Coli (LT), its B Subunit (LTB) and LT-R192G, but not The B Subunit of CT (CTB), induce the Decrease of Resting CD4+CD25+Foxp3+ T Cells in Vitro

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Immunomodulation Using Bacterial Enterotoxins

Liljana Petrovska

Scandinavian Journal of Immunology, 2001

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Modulation of Innate and Acquired Immune Responses by Escherichia coli Heat-Labile Toxin: Distinct Pro- and Anti-Inflammatory Effects of the Nontoxic AB Complex and the Enzyme Activity

Elizabeth J Ryan

The Journal of Immunology, 2000

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The mucosal adjuvant effects of cholera toxin and immune-stimulating complexes differ in their requirement for IL-12, indicating different pathways of action

Elisabeth Hörnquist, Nils Lycke

European Journal of Immunology, 1999

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Recombinant Antigen-Enterotoxin A2/B Chimeric Mucosal Immunogens Differentially Enhance Antibody Responses and B7-Dependent Costimulation of CD4 + T Cells

T. Connell

Infection and Immunity, 2001

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Escherichia coliHeat-Labile Enterotoxin B Subunit Is a More Potent Mucosal Adjuvant than Its Closely Related Homologue, the B Subunit of Cholera Toxin

Denis Snider

Infection and Immunity, 2001

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Chimeras of Labile Toxin One and Cholera Toxin Retain Mucosal Adjuvanticity and Direct Th Cell Subsets Via Their B Subunit

Prosper Boyaka

The Journal of Immunology, 2003

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A Nontoxic Chimeric Enterotoxin Adjuvant Induces Protective Immunity in Both Mucosal and Systemic Compartments with Reduced IgE Antibodies

Kohtaro Fujihashi

The Journal of Infectious Diseases, 2002

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Oral administration of recombinant cholera toxin subunit B inhibits IL-12 mediated murine experimental colitis

Monica Boirivant

Gastroenterology, 2000

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Cholera toxin and Salmonella typhimurium induce different cytokine profiles in the gastrointestinal tract

D. Niesel

Infection and immunity, 1995

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Distinctive Immunomodulatory and Inflammatory Properties of the Escherichia coli Type II Heat-Labile Enterotoxin LT-IIa and Its B Pentamer following Intradermal Administration

Juliana Rodrigues

Clinical and Vaccine Immunology, 2011

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Enhanced antigen uptake by dendritic cells induced by the B pentamer of the type II heat-labile enterotoxin LT-IIa requires engagement of TLR2

Lorrie Campbell

Vaccine, 2010

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In Vitro Induction of Immunoglobulin A (IgA)- and IgM-Secreting Plasma Blasts by Cholera Toxin Depends on T-Cell Help and Is Mediated by CD154 Up-Regulation and Inhibition of Gamma Interferon Synthesis

Sergio Arce

Infection and Immunity, 2007

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Oral Administration of Recombinant Cholera Toxin Subunit B Inhibits IL-12-Mediated Murine Experimental (Trinitrobenzene Sulfonic Acid) Colitis

Mariateresa De Pascale

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Mucosal immunogenicity and adjuvant activity of the recombinant A subunit of the Escherichia coli heat-labile enterotoxin

Lolke de Haan

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Cholera toxin improves the F4(K88)-specific immune response following oral immunization of pigs with recombinant FaeG

Eric Cox

Veterinary Immunology and Immunopathology, 2005

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Intranasal Immunogenicity and Adjuvanticity of Site-Directed Mutant Derivatives of Cholera Toxin

Maria Fontana

Infection and Immunity, 1997

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Enterotoxin-Specific Immunoglobulin E Responses in Humans after Infection or Vaccination with Diarrhea-Causing Enteropathogens

Muhammad Al JAhwary

Infection and Immunity, 2000

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Nasal Cholera Toxin Elicits IL-5 and IL-5 Receptor α-Chain Expressing B-1a B Cells for Innate Mucosal IgA Antibody Responses

Kohtaro Fujihashi

The Journal of Immunology, 2007

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Induction and Distribution of Intestinal Immune Responses after Administration of Recombinant Cholera Toxin B Subunit in the Ileal Pouches of Colectomized Patients

M. Quiding-Jarbrink, J. Kilhamn

Infection and Immunity, 2001

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Increased Antigen Specific T Cell Numbers in the Absence of Altered Migration or Division Rates as a Result of Mucosal Cholera Toxin Administration

Maria Kaparakis Liaskos

PLoS ONE, 2013

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Transcutaneous Immunization with Cholera Toxin B Subunit Adjuvant Suppresses IgE Antibody Responses Via Selective Induction of Th1 Immune Responses

Cecil Czerkinsky

The Journal of Immunology, 2003

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