Frequency of Anemia in Patients Presented with Chronic Obstructive Pulmonary Disease (original) (raw)
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Prevalence of anemia in patients with chronic obstructive pulmonary disease
2011
Objective: Chronic obstructive pulmonary disease (COPD) is associated with significant morbidity and mortality worldwide. This disease affects the lungs and organs outside the lungs. The aim of this study was to determine the prevalence of anemia in patients who were referred to teaching hospitals of Tehran University of Medical Sciences, Tehran, Iran. Methodology: Three hundred ninety two patients with COPD who attended to the teaching hospitals of Tehran University of Medical Sciences, from March to June 2009 were assessed. Laboratory and clinical data of patients was gathered from their medical records. We used global initiative for chronic obstructive lung disease criteria in order to categorize severity of disease in patients. Results: The mean age of patients was 66.5±12.3 years and 289 (73.7%) subjects were men. The overall prevalence of anemia was 36.7% (95% CI: 31%-41%). Twenty two females (21.4%) and 110 males (38.1%) were anemic. There was a positive correlation between a...
ANEMIA AND CHRONIC OBSTRUCTIVE PULMONARY DISEASES
Objective: To determine the frequency of Anemia in patients with chronic obstructive pulmonary disease (COPD). Material and Methods: This Cross-sectional study was conducted in Pulmonology Ward of Khalifa Gul Nawaz Teaching Hospital, Bannu from September 2012 to May 2013. All male and female patients of age 40 years and above were included having COPD according to the crіteria of Pakistan Chest Society. Sample size was 241 and sampling technique was of non probability convenient type. Hemoglobin (Hb) level of every patient was assessed for anemia. Data was analyzed in SPSS version 16 for descriptive statistics. Results: A total of 241 COPD patients were included in this study. Female patients exceeded male, with 129(53.5%) females. Mean age was 63 years ± 11.38 SD. All the patients had variable duration of COPD. Seventy patіents had COPD for <5 years, 128 patіents for 6-20 years, 43 patients had COPD for 21 years and above Anemіa was confirmed in 180 (74.7%) patіents. Among these cases, 100 (55.55%) were female and the remaining 80 (44.44%) were male. Conclusion: COPD patients had a hіgh prevalence of anemia, and failure to address this may lead to morbidity and mortality. Key Words: COPD, Anemia, Hemoglobin.
Prevalence of Anemia in Patients with COPD and Its Potential Impact on Morbidity of COPD Patients
International Journal of Clinical Medicine, 2014
Background: Although COPD is traditionally associated with polycythemia, the systemic inflammation that is now recognized as a feature of COPD makes it a possible cause of Anemia of Chronic Disease (ACD). Preliminary evidences suggest that anemia in COPD may be more prevalent than expected occurring in 10% -15% of patients. While in states like chronic heart failure and renal insufficiency, anemia has been extensively studied; little attention has been given to it in COPD. Objectives: To see the prevalence of anemia in patients with COPD and its potential impact on morbidity of COPD patients. Design and Setting: A university hospital-based cross-sectional study in Kashmir, India. Methods: Two hundred patients (119 males and 81 females) with spirometery documented COPD were evaluated for frequency of anemia. In addition to routine investigations, erythropoietin levels were done in a subgroup of patients. Results: A total of 36 cases (20 males and 16 females) of anemia were detected giving a frequency of 18%. Normocytic normochromic type of anemia was present in 32 (88.89%) patients while the rest had normocytic hypochromic type of anemia. Majority of patients were in GOLD stage 11 and had decreased serum iron, transferrin saturation and TIBC. Erythropoietin levels were significantly raised in anemic COPD patients compared to non-anemic COPD patients. The various factors significantly associated with anemia were: No. of exacerbations of COPD, No. of hospital admissions, BMI and erythropoietin levels. Conclusion: Anemia occurs frequently in patients of COPD and is associated with increased morbidity in the form of No. of exacerbations and hospital admissions. Correcting anemia in these patients may improve their clinical outcome.
Journal of Enam Medical College, 2014
Background: Chronic obstructive pulmonary disease (COPD) is usually associated with polycythemia. It is assumed that systemic inflammatory components of COPD can interfere with erythropoietin and can result in anemia of chronic disease which will impair the functional capacity of these patients and also increase morbidity and mortality. Objective: To evaluate anemia status in COPD patients. Materials and Methods: This cross-sectional study was conducted in clinically stable 50 COPD patients in the outpatient department of Medicine in Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka during the period of July to December 2011. The demographic characteristics, smoking habit, duration of disease, types and severity of anemia, BMI and results of 6-minute walk test were recorded. Results: Out of 50 COPD patients, 76% were male and 24% were female. Among them 32% patients were anemic, 20% were polycythemic and 48% patients had normal hemoglobin. Among the anemic patients with COPD, 87% were male and 13% were female,75% were mildly anemic and 4% moderately anemic, 62.5% had normocytic and 37.5% had microcytic anemia. Conclusion: Anemia in COPD patients is often overlooked and underestimated. Clinicians should be aware of the presence of anemia in patients with COPD so that appropriate treatment could be initiated to improve the quality of life and prognosis.
Impact of anemia on functional state of patients with chronic obstructive pulmonary disease
Background: The occurrence and prevalence of anemia in patients with chronic obstructive pulmonary disease (COPD) has been little studied. Recent studies prove that anemia in patients with COPD is highly prevalent and associated with increased mortality. Anemia is such a common and simple clinical finding that its real physiologic relevance in COPD can be frequently underestimated. The aim of this study was to determine the prevalence of anemia in patients with COPD and to analyse the associations between hemoglobin levels and some clinical outcomes. Methods: 158 consecutive patients with COPD were recruited into the study. Spirometry (FEV1, FVC, FEV1/FVC), hemoglobin levels, dyspnoea by MRC scale, exercise capacity by 6-minute walking distance (6MWD) test, the BODE index were evaluated. The comorbidities were assessed by Charlson Comorbidity Index (CCI). Results: All patients were distributed according to the age in 2 groups: 80 elderly patients, mean age 72.2 ± 4.82 years and 78 y...
National Journal of Medical Research, 2015
Background & Objectives: Anemia is a common co-existing entity in numerous chronic diseases like COPD, but has little published evidence stating its association with this disease. The effect of COPD on the health related quality of life and mortality in COPD patients, also remains least explored. The recent studies have suggested that anemia in patients with COPD has a frequent prevalence ranging from 7.5% to 34%. This data indicate towards the necessity of knowing the real prevalence and clinical impact of Anaemia of Chronic Disease in COPD and how does it affect their Health Related Quality of Life. Methods: This study was conducted on all consecutive stable COPD patients and related data was recorded. The St George Respiratory Questionnare (SGRQ) and the BODE index (Body Mass Index, FEV1, Dyspnoea, Exercise Capacity) was used to analyze the Health Related Quality of Life and the morbidity level of included patients. Results: 32 COPD patients had anaemia. The analysis showed significantly higher symptom score in the anaemic COPD patients (p=0.04). Also anaemics had significantly lesser BMI (p=0.03), significantly poor dyspnoea score (p=0.05) and significantly lesser six minute walk distance (p=0.05). Conclusions: The prevalence of anaemia in stable COPD patients is 32%, which is significantly associated with low BMI, dyspnoea and reduced exercise capacity. These factors can affect the quality of life of COPD patients thus, leading to increased morbidity. Hence, treating anaemia should hold a special place in treatment regime for COPD.
To Identify Whether Anemia is related to Hospital Mortality in COPD Exacerbations
2021
Introduction: Anemia of chronic disease (ACD) is an immune-driven abnormality associated with chronically very low levels of circulating hemoglobin that has been found to existing in various inflammatory diseases. The aim of this study evaluated whether the degree of anemia affects the survival of patients with COPD. Material and methods: A Hospital based observational study concluded with 100 patients admitted in ICU of Mahatma Gandhi Medical College & Hospital, Jaipur during the period of January 2019 to June 2020 with COPD exacerbation. COPD diagnosis was established with GOLD clinical criteria. Anemia was defined as hemoglobin levels <12 gm/dL for female patients and <13 gm/dL for male patients according to the World Health Organization (WHO) anemia definition. Initial mechanical ventilation support type, failure in NIV, total duration of mechanical ventilation support, the lengths of ICU and hospital stays, and ICU and hospital mortality were recorded. Results: Our study ...
Clinical impact of anemia in patients with COPD
The European respiratory journal. Supplement
Metabolic syndrome frequency has been reported to be increased in COPD.Intima media thickness (IMT) increases in both coronary and peripheral arteries at early stages of atherosclerosis. Aims and objectives: We aimed to investigate the frequency of metabolic syndrome and carotid IMT in COPD patients which may contribute to the evaluation cardiovascular risks. Methods: Fifty-one stable COPD patients admitted to our clinic were included. Blood pressure, pulse, weight, height and waist circumference were measured. Fasting blood glucose, triglyceride, high density lipoprotein levels were analyzed in the venous blood samples obtained at the same day.Metabolic syndrome defined as abdominal obesity, atherogenic dyslipidemia, increased blood pressure, insulin resistance was evaluated.Afterwards, bilateral carotid doppler ultrasonography was performed.A focal IMT≥1 mm was defined as increased IMT. Results: Mean age of 51 patients was 64±18.Eight percentages of the patients were stage 1, 33% were stage 2, 43% were stage 3, 16% were stage 4 according to GOLD. Mean FEV1% was 48±21 and mean IMT was 1,11±0,24 micrometer. Metabolic syndrome was determined in 43% of the patients. Metabolic syndrome prevalence was correlated with COPD stage and FEV1% (p=0.009,r=0,365;p=0,031,r=-0,303,respectively), however it was not found to be related with disease duration and smoking history.Carotid IMT did not show any relationship between disease duration, stage and FEV1. It was also not correlated with metabolic syndrome. Conclusion: Our results demonstrated increased frequency of metabolic syndrome in COPD patients as well as carotid IMT; an early marker atherosclerosis was over the upper limit of normal.