The β and α2δ auxiliary subunits of Cav1 channels are required for Th2-lymphocyte function and acute allergic airway inflammation (original) (raw)

Knocking Down Cav1 Calcium Channels Implicated in Th2 Cell Activation Prevents Experimental Asthma

Bruno Gomes

American Journal of Respiratory and Critical Care Medicine, 2010

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Role of the ion channel, transient receptor potential cation channel subfamily V member 1 (TRPV1), in allergic asthma

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Protein kinase C–dependent activation of CaV1.2 channels selectively controls human TH2-lymphocyte functions

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Allergens stimulate store-operated calcium entry and cytokine production in airway epithelial cells

Murali Prakriya

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Severely blunted allergen-induced pulmonary Th2 cell response and lung hyperresponsiveness in type 1 transient receptor potential channel-deficient mice

Alexander Dietrich

AJP: Lung Cellular and Molecular Physiology, 2012

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Calcium-sensing receptor antagonists abrogate airway hyperresponsiveness and inflammation in allergic asthma

William Ford

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Malcolm Shepherd

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Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction

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D. Matza

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Store-Operated Ca2+ Release-Activated Ca2+ Channels Regulate PAR2-Activated Ca2+ Signaling and Cytokine Production in Airway Epithelial Cells

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Increased expression of bronchial epithelial transient receptor potential vanilloid 1 channels in patients with severe asthma

SADAF ASHRAF

Journal of Allergy and Clinical Immunology, 2014

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Sustained Calcium Entry through P2X Nucleotide Receptor Channels in Human Airway Epithelial Cells

Erik Schwiebert

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Ca(2+) signaling in T-cell subsets with a focus on the role of cav1 channels: possible implications in therapeutics

Magali Savignac

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Singularities of calcium signaling in effector T-lymphocytes

Magali Savignac

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2013

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Critical role for the regulatory subunits of Cav channels in T lymphocyte function

Wajahat Mehal

Proceedings of the National Academy of Sciences, 2006

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Loss of classical transient receptor potential 6 channel reduces allergic airway response

Benjamin Rost

Clinical & Experimental Allergy, 2008

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Requirement of voltage-gated calcium channel beta4 subunit for T lymphocyte functions

Leonard Kaczmarek

Science (New York, N.Y.), 2005

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The α2δ subunit augments functional expression and modifies the pharmacology of CaV1.3 L-type channels

Ricardo Felix

Cell Calcium, 2009

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The role of CRAC channel in asthma

Kristof Raemdonck

Pulmonary Pharmacology & Therapeutics, 2015

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Cavβ1 regulates T cell expansion and apoptosis independently of voltage-gated Ca2+ channel function

Murali Prakriya

Nature Communications, 2022

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T Cell Receptor Mediated Calcium Entry Requires Alternatively Spliced Cav1.1 Channels

Usha Govindarajulu, PhD

PLOS ONE, 2016

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TRPM2 channels are not required for acute airway inflammation in OVA-induced severe allergic asthma in mice

Adriana Sumoza-Toledo

Journal of Inflammation, 2013

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Interleukin-4 activates large-conductance, calcium-activated potassium (BKCa) channels in human airway smooth muscle cells

Steven Treistman

Experimental Physiology, 2008

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