The efficacy of hyaluronic acid gel on postoperative sequelae following extraction of impacted lower third molars (original) (raw)
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International Journal of Research in Pharmaceutical Sciences
The surgical removal of third molar is the commonly performed procedure in oral and surgery. It takes several days to recover from the complications following removal of the third molar. The common postoperative complications are pain, swelling, , alveolar after third molar removal The aim of this systematic review was to thoroughly the existing literature to evaluate the effect of socket versus extra socket application of acid gel in management of postoperative complications after third molar removal. The objective of this systematic review is to assess the efficacy of socket versus extra socket application of acid gel compared to placebo or no treatment in management of post-operative complications after removal of third molar.The data bases of PubMed, and google scholar were searched for the related topics along with a complimentary manual search of all oral surgery journals till October 2018.The data collection form was based on analysis of included studies for their quality ass...
Background: Removal of impacted third molars is associated with postoperative complications such as pain, swelling, ecchymosis, trismus, infection, and hematoma. Thus, contemporary surgery aims to reduce complications by applying collagen or hyaluronic acid in the socket after extracting the impacted mandibular third molars.This study aimed to study the efficacy of Hyaluronic Acid (HA) addition to collagen, compared to collagen application alone, on the magnitude of swelling and trismus following impacted mandibular third molar surgery.Methods: About 20 patients underwent impacted bilateral lower third molars surgery (n = 40). Opaque envelopes carried out randomization; two materials were applied topically in the socket collagen alone or with hyaluronic. The post-operative mouth-opening limitation and swelling rate were assessed on the third and seventh days after the extraction. Results: The mean age was 22.7 ± 3.079 years (75% female, 25% male). A statistically significant differe...
International Journal of Advanced Research
Aim of the study: To determine the efficacy of Hyaluronic acid gel in management of postoperative complications after impacted mandibular third molar surgery. Materials and Method : This prospective, single-centeredstudy follow a split mouth-design, where the patients were act as their own control. A total of 40 patients were included in study.The study subjects were assigned into two groups: Control Group and Study Group (0.8 % Hyaluronic acid gel). Once selected, each patient will be assigned a serial number. According to their respective serial numbers, patients with odd serial number will be administered 2ml 0.8% hyaluronic acid gel (Gengigel ) in the postextraction socket of impacted mandibular third molar of the left side, and the right side will act as control, an interval of 4 weeks is kept between the 2 surgeries. In even numbered patients, the right side extraction socket will be administered 2 ml 0.8 % hyaluronic acid gel (Gengigel)and the left side acted as the control. ...
2018
Aim and objective: The aim of this study was compare the efficacies of two oral sprays in reducing swelling, pain, and trismus after the extraction of impacted mandibular third molars. Materials and method: This prospective double-blind, randomized, crossover clinical trial included 30 patients with bilateral symmetrically impacted mandibular third molars of similar surgical difficulty. Hyaluronic acid or Normal saline spray was applied (two pumps) to the extraction area, three times daily for 7 days. Swelling was evaluated using a tape measure method, pain with a visual analogue scale (VAS), and trismus by measuring the maximum inter-incisal opening. Assessments were made on the day of surgery and on days 2 and 7 after surgery. Result: Statistically significant differences were detected for the swelling and trismus values between the two treatment groups on the second postoperative day (P = 0.000 and P = 0.024, respectively). However, there was no statistically significant differen...
Effect of Hyaluronic Acid Gel on Healing of Simple Dental Extraction Sockets: A Pilot Study
Open Access Macedonian Journal of Medical Sciences
BACKGROUND: Hyaluronic acid (HA) was explored as a powerful positive biocompatible material that participates in numerous biological processes related to morphogenesis and tissue healing. AIM: In this context, we elevated in this pilot study the effect of HA on soft tissue healing and bone repair of dental sockets (DS) as well as the postoperative pain. MATERIALS AND METHODS: Ten individuals of both genders (80% females and 20% males) with age range 18–44 years, were included who were diagnosed with two non-restorable teeth (total sockets n = 20). A split-mouth study design was performed where the DS of each patient were divided into Group A (study group): Topical oral HA gel (Gengigel®) was applied into sockets while Group B (control group): Sockets were left untreated. Study variables were evaluated including socket length, socket healing scores (healing index), and post-operative pain in both groups at day 1, 5, and 10 for each patient. RESULTS: There were no statistically signif...
Surgical extraction of impacted lower wisdom teeth is a frequent minor intraoral surgical process. It is regularly linked with aching and postoperative consequences as pain and swelling. The aim of this study is to evaluate the efficacy of two methods in reducing swelling and pain subsequent to the removal of impacted wisdom teeth. This randomized study incorporated 20 patients with impacted wisdom teeth of different surgical complexity. Topical hyaluronic acid gel 2g/2ml with aloe vera (Kin®Care) was given to the patients to be applied to the surgical area three times a day, or diclofenac sodium tablet 50mg (Voltaren®) to be taken every eight hours, for one week. Swelling was estimated using a strip gauge technique, and pain with a visual analogue scale. Evaluations were made on day one of surgical treatment and on 72hrs and one week later. Statistically no significant differences were identified regarding the swelling and pain values between the two treatment groups on the third and seventh day after surgery. Hyaluronic acid gel was as efficient as diclofenac tablets in reducing the two parameters. The use of hyaluronic acid may be advantageous in medically compromised patient such as those with hypertension, chronic asthma, gastric ulcers or in those with any contraindications to using non-steroidal anti-inflammatory drugs, or in pregnant patients to reduce pain and swelling subsequent to impacted wisdom teeth surgery.
Journal of Clinical Medicine
Surgical removal of mandibular third molars is associated with non-infectious postoperative complications, including pain, swelling, trismus. Intraoral drains are noteworthy because of their ease of application, availability, and effectiveness. This study aimed to evaluate the use of latex and calcium–sodium alginate mouth flat drains on the severity of postoperative complications such as pain, trismus, and edema after surgical removal of mandibular third molars. Ninety patients who underwent surgical removal of wisdom teeth were studied. The patients were divided into three groups. Group A—with a latex flat drain, group B—with a sodium–calcium alginate (Kaltostat) flat drain, and group C—with a wound closed with knotted sutures. Patients were assessed for pain on a VAS scale every day from surgery to postoperative day 7. Before the procedure and on postoperative days 1, 2, and 7, the pain level, edema, and trismus were measured, respectively. Intraoral drainage with a flat drain af...
International journal of health sciences, 2022
Odontostomologic procedures like extractions especially surgical removal of impacted 3rd molars, implants, biopsies etc are often associated with post-operative pain and inflammation. Traditionally chlorhexidine was used in this regard. Recently, topical gel, Bexident Post (ISDIN, SPAIN) has been in use to control post-operative discomfort. The aim of this study is to clinically evaluate the efficacy of Bexident Post (ISDIN, SPAIN) that contains chitosan, dexpenthanol, allantoin and 0.2% chlorhexidine on wound healing after surgical extraction of mandibular impacted 3rd molars. A study sample of 10 patients with similar type of bilateral impacted mandibular 3rd molar was included in the study. Total of 10 extractions were assingned in one of the two groups. Only difference between the two sides in terms of surgical protocol will be the Experimental side applied 10 mL thrice daily for 10 days while Control side did not. All patients were aware of the purpose of present study and writ...