Context-dependent signaling defines roles of BMP9 and BMP10 in embryonic and postnatal development (original) (raw)

Molecular basis of ALK1-mediated signalling by BMP9/BMP10 and their prodomain-bound forms

Jingxu Guo

Nature Communications, 2020

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Identification of BMP9 and BMP10 as functional activators of the orphan activin receptor-like kinase 1 (ALK1) in endothelial cells

J.-j. Feige

Blood, 2007

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Anti-human Activin Receptor-like Kinase 1 (ALK1) Antibody Attenuates Bone Morphogenetic Protein 9 (BMP9)-induced ALK1 Signaling and Interferes with Endothelial Cell Sprouting

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Journal of Biological Chemistry, 2012

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SM22 -targeted deletion of bone morphogenetic protein receptor 1A in mice impairs cardiac and vascular development, and influences organogenesis

Christophe Guignabert

Development, 2008

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BMP-9 induces proliferation of multiple types of endothelial cells in vitro and in vivo

Kyoko Hida

Journal of Cell Science, 2010

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BMP-9 signals via ALK1 and inhibits bFGF-induced endothelial cell proliferation and VEGF-stimulated angiogenesis

L. Pukac

Journal of Cell Science, 2007

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SM22α-targeted deletion of bone morphogenetic protein receptor 1A in mice impairs cardiac and vascular development, and influences organogenesis

Christophe Guignabert

Development, 2008

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Advances in the molecular regulation of endothelial BMP9 signalling complexes and implications for cardiovascular disease

Jingxu Guo

Biochemical Society Transactions, 2019

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BMP9 Induces Cord Blood-Derived Endothelial Progenitor Cell Differentiation and Ischemic Neovascularization via ALK1

Wook-bin Lee

Arteriosclerosis, thrombosis, and vascular biology, 2015

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Bone Morphogenetic Protein (BMP) Type II Receptor Deletion Reveals BMP Ligand-specific Gain of Signaling in Pulmonary Artery Smooth Muscle Cells

Charles Hong

Journal of Biological Chemistry, 2005

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BMPER, a Novel Endothelial Cell Precursor-Derived Protein, Antagonizes Bone Morphogenetic Protein Signaling and Endothelial Cell Differentiation

Christoph Bode

Molecular and Cellular Biology, 2003

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Bone morphogenetic protein receptor 1A signaling is dispensable for hematopoietic development but essential for vessel and atrioventricular endocardial cushion formation

Kory Lavine

Development, 2006

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Alk2/ACVR1 and Alk3/BMPR1A Provide Essential Function for Bone Morphogenetic Protein–Induced Retinal Angiogenesis

Vesa Kaartinen

Arteriosclerosis, Thrombosis, and Vascular Biology, 2017

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The essential role of bone morphogenetic protein (BMP) signaling in organogenesis

Rongqin Ren

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Modulation of activin and BMP signaling

Craig Harrison

Molecular and Cellular Endocrinology, 2004

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Alk2/ACVR1 and Alk3/BMPR1A Provide Essential Function for Bone Morphogenetic Protein–Induced Retinal AngiogenesisHighlights

Vesa Kaartinen

Carolina Digital Repository (University of North Carolina at Chapel Hill), 2017

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Bone morphogenetic protein 9 (BMP9) and BMP10 enhance tumor necrosis factor-α-induced monocyte recruitment to the vascular endothelium mainly via activin receptor-like kinase 2

Claudia Mitrofan

Journal of Biological Chemistry, 2017

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Specificity and Structure of a High Affinity Activin Receptor-like Kinase 1 (ALK1) Signaling Complex

Jasbir Seehra

Journal of Biological Chemistry, 2012

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Endothelial Expression of Bone Morphogenetic Protein Receptor Type 1a is Required for Atrioventricular Valve Formation

Stuart Jamieson

The Annals of Thoracic Surgery, 2008

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BMP10 is essential for maintaining cardiac growth during murine cardiogenesis

Mervin Yoder

Development, 2004

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BMPER Is an Endothelial Cell Regulator and Controls Bone Morphogenetic Protein-4-Dependent Angiogenesis

Christoph Bode

Circulation Research, 2008

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Genetic and pharmacological targeting of activin receptor-like kinase 1 impairs tumor growth and angiogenesis

Jasbir Seehra

Journal of Experimental Medicine, 2010

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The Bone Morphogenetic Protein Antagonist Noggin Regulates Mammalian Cardiac Morphogenesis

Murim Choi

2009

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Bone Morphogenetic Protein-9 Controls Pulmonary Vascular Growth and Remodeling

Christophe Guignabert

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Deficient Signaling via Alk2 (Acvr1) Leads to Bicuspid Aortic Valve Development

Vesa Kaartinen

PLOS ONE, 2012

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Bone morphogenetic protein (BMP) 9 and BMP10 enhance tumor necrosis factor-α-induced monocyte recruitment to the vascular endothelium mainly via activin receptor-like kinase 2

Claudia Mitrofan

2017

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Activin A inhibits BMP-signaling by binding ACVR2A and ACVR2B

Karin Wader, Ingerid Nesthus, Oddrun Olsen, Anders Waage

Cell Communication and Signaling, 2015

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Bone Morphogenetic Protein-9 Is a Circulating Vascular Quiescence Factor

Jean-jacques Feige

Circulation Research, 2008

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