Novel Types of Staphylococcal Cassette Chromosome mec Elements Identified in Clonal Complex 398 Methicillin-Resistant Staphylococcus aureus Strains (original) (raw)

2011, Antimicrobial Agents and Chemotherapy

The structures of staphylococcal cassette chromosome mec (SCC mec ) elements carried by 31 clonal complex 398 (CC398) methicillin-resistant Staphylococcus aureus (MRSA) strains isolated from the participants at a conference were analyzed. The SCC mec s were classified into novel types, namely, IX, X, V(5C2&5) subtype c, and IVa. Type V(5C2&5) subtype c, IX, and X SCC mec s carried genes conferring resistance to metals. The structures of SCC mec s from CC398 strains were distinct from those normally found in humans, adding to the evidence that humans are not the original host for CC398.

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