Valbenazine and Trazodone overdose in a patient taking LAI and oral Paliperidone (original) (raw)

Valbenazine, a recently approved drug for tardive dyskinesia, was safely overdosed in a patient with schizoaffective disorder, indicating it may pose low risk even in conjunction with Trazodone. This case report details a 43-year-old male who overdosed on Valbenazine and Trazodone but experienced no significant medical sequelae, highlighting QTc prolongation as a risk factor that did not result in adverse events in this instance. The findings suggest that while monitoring for QTc prolongation is necessary, Valbenazine may be safer in overdose situations than previously anticipated.