Metaplastic ossification in a juvenile rectal polyp: A rare histological finding (original) (raw)
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Osseous Metaplasia in Rectal Polyp: A Case Report with Review of Probable Pathogenesis
Advanced biomedical research, 2018
Heterotopic bone formation is a rare event in gastrointestinal lesions, especially in the pediatric population. Osseous metaplasia is exceedingly rare in colonic polyps. We present a case of rectal juvenile polyp with stromal osseous metaplasia in a 10-year-old male child. This histologic finding is very rare in children with colorectal polyps.
Juvenile Rectal Polyp with Osseous Metaplasia - A Rare Case with Review of Literature
2012
Heterotopic bone formation (osseous metaplasia) is rarely detected in the gastrointestinal tract. We report a unique case of juvenile rectal polyp occurring in a 5 year old female child which showed osseous metaplasia. This phenomenon is detected at histology but has no clinical significance. Literature with regard to the pathogenesis of osseous metaplasia is reviewed.
Rectal Polyp with Osseous Metaplasia: A Case Report and Review of the Literature
Annals of Colorectal Research
An osseous metaplasia in colonic tissue is extremely rare. The current report presents a case of osseous metaplasia in a hamartomatous rectal polyp in a four-year-old boy, who presented with intermittent rectal bleeding. Though this condition has minimum adverse effects on the prognosis of the patient, awareness of this rare histological variant is of utmost importance.
Cancer, 1979
The pathogenesis of juvenile polyps of the colon was studied in a patient with multiple juvenile polyposis who underwent proctocolectomy for rectal carcinoma and antrectomy for associated polyps of the stomach. Numerous polyps up to 3 cm in diameter were present predominantly in the cecum and rectum, and in addition there was an adenocarcinoma in the rectum. Microscopically there were five categories of lesions: 1) Hyperplastic epithelial foci and small hyperplastic polyps; 2) Typical Juvenile polyps; 3) Juvenile polyps with focal adenomatous epithelium; 4) Adenomas; and 5) an adenocarcinoma. The five categories could represent a pathogenetic sequence, beginning with epithelial hyperplasia, leading to small hyperplastic polyps which become inflamed and enlarge, forming juvenile polyps. Focal adenomatous areas which develop in some juvenile polyps might give rise to adenomas and in turn lead to carcinoma. Although juvenile polyps are generally not considered to be premalignant lesions, this case demonstrates that neoplastic changes may occur in juvenile polyps in certain individuals, and raises the possibility that these may on occasion give rise to carcinoma.
Heterotopic Ossification in Gastrointestinal Neoplasms: A Rare Occurrence
https://www.ijhsr.org/IJHSR\_Vol.8\_Issue.8\_Aug2018/IJHSR\_Abstract.049.html, 2018
Osseous metaplasia is described in a variety of organs in both neoplastic and non-neoplastic conditions. In gastrointestinal tract, it is a very rare phenomenon. Only few cases have been reported in literature in colonic polyps especially in juvenile polyps and colonic malignancies. We report three cases of heterotopic ossification in juvenile polyp and one in colonic adenocarcinoma with review of literature. Many mechanisms of its pathogenesis are hypothesized but exact cause remains still unclear
Srpski arhiv za celokupno lekarstvo, 2019
Introduction. Osseous metaplasia is a heterotopic formation of bone and its appearance in benign gastrointestinal polyps is exceedingly rare. The mechanism responsible for this type of metaplasia is not fully understood, however it seems to be an innocent rare phenomenon. Case outline. We present a case of a 31-year-old male with mesenchimal osseal metaplasia in a large inflamatory polyp measuring 57 ? 23 ? 20 mm in diameter, located in the anal canal region. Conclusion. According to our knowledge, this is the largest gastrointestinal polyp with osseous metaplasia described so far. Although a rare phenomenon, there are certain characteristics of this disease, so we conducted a literature review and summarized these characteristics.
Endoscopic Removal of Giant Rectal Polyp in a Child – A Case Report
2013
Solitary pedunculated juvenile rectal polyp is a recognized cause of painless rectal bleeding in preschool age children; however, giant juvenile polyps (greater than 30 mm) are exceedingly rare in children. A 10 year old boy with prior history of something coming out of rectum for one year presented with sudden onset of massive painless hematochezia. On evaluation a giant rectal polyp measuring 3 x 3 x 2 cm was found and removed endoscopically. Histological evaluation revealed juvenile adenomatous polyp. To best of our knowledge this is the second case reported where the giant rectal polyp was removed endoscopically in pediatric age group.(J Dig Endosc 2013;1(4):.................) Giant rectal polyp – Endoscopic polypectomy – Child