Apoptotic signaling by c-MYC (original) (raw)

c-Myc antagonizes the effect of p53 on apoptosis and p21WAF1 transactivation in K562 leukemia cells

Javier León

Oncogene, 2000

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p53-independent apoptosis associated with c-Myc-mediated block in myeloid cell differentiation

Barbara Hoffman

Oncogene, 2000

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A role for c-myc in DNA damage-induced apoptosis in a human TP53-mutant small-cell lung cancer cell line

Paola Perego

European Journal of Cancer, 2001

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Inhibitory effect of c-Myc on p53-induced apoptosis in leukemia cells. Microarray analysis reveals defective induction of p53 target genes and upregulation of chaperone genes

Javier León

Oncogene, 2005

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c-Myc Augments Gamma Irradiation-Induced Apoptosis by Suppressing Bcl-XL

John Cleveland

Molecular and Cellular Biology, 2003

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Induction of cell cycle progression and acceleration of apoptosis are two separable functions of c-Myc: transrepression correlates with acceleration of apoptosis

Michael O'Leary

Molecular and cellular biology, 2000

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c-Myc potentiates the mitochondrial pathway of apoptosis by acting upstream of apoptosis signal-regulating kinase 1 (Ask1) in the p38 signalling cascade

Katia Desbiens, Jacques Landry

Biochemical Journal, 2003

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Integrated Control of Cell Proliferation and Cell Death by the c-myc Oncogene

Hartmut Land

Philosophical Transactions of the Royal Society B: Biological Sciences, 1994

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Apoptosis-prone phenotype of human colon carcinoma cells with a high level amplification of the c-myc gene

Maddalena Donzelli

Oncogene, 1999

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c-Myc-induced sensitization to apoptosis is mediated through cytochrome c release

Trevor Littlewood

Genes & Development, 1999

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Differential apoptotic behaviors of c-myc, N-myc, and L-myc oncoproteins

Edward Prochownik

Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1998

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Quantitative Proteomic Analysis of Myc-induced Apoptosis

hookeun lee

Journal of Biological Chemistry, 2005

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c-Myc depletion inhibits proliferation of human tumor cells at various stages of the cell cycle

Edward Prochownik

2007

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Activation of c-myc gene expression by tumor-derived p53 mutants requires a discrete C-terminal domain

Mark Frazier

… and cellular biology, 1998

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Myc down-regulation induces apoptosis in M14 melanoma cells by increasing p27kip1 levels

Armando Felsani

Oncogene, 2001

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N-Myc downstream-regulated gene 2 is involved in p53-mediated apoptosis

Hua Han

Nucleic Acids Research, 2008

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Targeting of MCL-1 kills MYC-driven mouse and human lymphomas even when they bear mutations in p53

Stefan Glaser

Genes & Development, 2014

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c-Myc overexpression sensitises colon cancer cells to camptothecin-induced apoptosis

DANIEL RODRIGUEZ ARANGO

British journal of cancer, 2003

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p53-Dependent Transcriptional Repression of c-myc Is Required for G1 Cell Cycle Arrest

Daniel Mao

Molecular and Cellular Biology, 2005

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A unique glucose-dependent apoptotic pathway induced by c-Myc

Yoon Chun

Proceedings of the National Academy of Sciences, 1998

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Apoptosis Triggered by Myc-Induced Suppression of BclXL or Bcl2 Is Bypassed during Lymphomagenesis

John Cleveland

Molecular and Cellular Biology, 2001

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c-Myc Blazing a Trail of Death: Coupling of the Mitochondrial and Death Receptor Apoptosis Pathways by c-Myc

Juha Klefstrom

Cell Cycle, 2007

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ATM promotes apoptosis and suppresses tumorigenesis in response to Myc

Raju Pusapati

Proceedings of The National Academy of Sciences, 2006

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Quiescence versus apoptosis: Myc abundance determines pathway of exit from the cell cycle

Geoffrey G Pinchbeck

Oncogene, 1998

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p53 is involved in the differentiation but not in the differentiation-associated apoptosis of myoblasts

Gianluca Bossi

Cell Death and Differentiation, 2000

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Genetic dissection of c-myc apoptotic pathways

Edward Prochownik

Oncogene, 2000

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C-myc overexpression and p53 loss cooperate to promote genomic instability

Edward Prochownik

Oncogene, 1999

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Inactivation of MYC reverses tumorigenesis

Dean Felsher

Journal of Internal Medicine, 2014

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p53 Has a Direct Apoptogenic Role at the Mitochondria

Petr Pancoska

Molecular Cell, 2003

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Identification of Myc-mediated Death Response Pathways by Microarray Analysis

Norman Lee

Journal of Biological Chemistry, 2002

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Inhibition of the Intrinsic but Not the Extrinsic Apoptosis Pathway Accelerates and Drives Myc-Driven Tumorigenesis Towards Acute Myeloid Leukemia

Lars-Gunnar Larsson

PLoS ONE, 2012

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Knockdown of c-MYC Controls the Proliferation of Oral Squamous Cell Carcinoma Cells in vitro via Dynamic Regulation of Key Apoptotic Marker Genes

International Journal of Molecular and Cellular Medicine

2021

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