Exposure to the complement C5b-9 complex sensitizes 661W photoreceptor cells to both apoptosis and necroptosis (original) (raw)

Retinal Pigment Epithelial Cells Mitigate the Effects of Complement Attack by Endocytosis of C5b-9

John Greenwood

Journal of immunology (Baltimore, Md. : 1950), 2015

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A Novel Role of Complement in Retinal Degeneration

Minzhong Yu

Investigative Ophthalmology & Visual Science, 2012

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Classical and alternative complement activation on photoreceptor outer segments drives monocyte-dependent retinal atrophy

Mike Reichelt

Scientific Reports, 2018

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Complement mediated apoptosis leads to the loss of retinal ganglion cells in animal model of glaucoma

Ruslana Tytarenko, Puran Bora

Molecular Immunology, 2011

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Analysis of Complement Expression in Light-Induced Retinal Degeneration: Synthesis and Deposition of C3 by Microglia/Macrophages Is Associated with Focal Photoreceptor Degeneration

Peter Kozulin, Matt Rutar, Paul Gatenby, Krisztina Valter

Investigative Ophthalmology & Visual Science, 2011

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Regulation of C3 Activation by the Alternative Complement Pathway in the Mouse Retina

Dimitris Stampoulis

PloS one, 2016

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Modulation of Retinal Müller Cells by Complement Receptor C5aR

Carlos Subauste

Investigative Ophthalmology & Visual Science, 2013

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Disruption of the complement cascade delays retinal ganglion cell death following retinal ischemia-reperfusion

Alina Dumitrescu

Experimental Eye Research, 2008

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Complement Proteins in the Retina in Cancer-Associated Retinopathy

John Demirs

JAMA Ophthalmology

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670-NM Light Treatment Reduces Complement Propagation Following Retinal Degeneration

Krisztina Valter

Journal of Neuroinflammation, 2012

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Human stem cell-derived retinal epithelial cells activate complement via collectin 11 in response to stress OPEN

Pete J Gardner

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Complement component C5a primes the NLRP3 inflammasome in retinal pigment epithelial cells

Tim U Krohne

2014

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Targeting the complement system for the management of retinal inflammatory and degenerative diseases

Heping Xu

European journal of pharmacology, 2016

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Distribution of complement anaphylatoxin receptors and membrane-bound regulators in normal human retina

Christine Curcio

Experimental Eye Research, 2006

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Complement modulation in the retinal pigment epithelium rescues photoreceptor degeneration in a mouse model of Stargardt disease

Roxana A Radu

Proceedings of the National Academy of Sciences of the United States of America, 2017

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Complement Component 1Q (C1Q) Upregulation in Retina of Murine, Primate, and Human Glaucomatous Eyes

Kali Stasi

Investigative Opthalmology & Visual Science, 2006

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Molecular Response of Chorioretinal Endothelial Cells to Complement Injury: Implications for Macular Degeneration

Shemin Zeng

The Journal of pathology, 2015

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A Systematic Investigation on Complement Pathway Activation in Diabetic Retinopathy

Subhabrata Chakrabarti

Frontiers in Immunology, 2020

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Effect of Anti-C5a Therapy in a Murine Model of Early/Intermediate Dry Age-Related Macular Degeneration

Catherine Bowes Rickman

Investigative ophthalmology & visual science, 2018

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Depletion of the Third Complement Component Ameliorates Age-Dependent Oxidative Stress and Positively Modulates Autophagic Activity in Aged Retinas in a Mouse Model

Ewa Pius-Sadowska

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Targeting the Complement Cascade for Treatment of Dry Age-Related Macular Degeneration

Harris Ahmed

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Oxidative Stress Sensitizes Retinal Pigmented Epithelial (RPE) Cells to Complement-mediated Injury in a Natural Antibody-, Lectin Pathway-, and Phospholipid Epitope-dependent Manner

Kusumam Joseph

Journal of Biological Chemistry, 2013

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Synthesis and Propagation of Complement C3 by Microglia/Monocytes in the Aging Retina

Krisztina Valter

PLOS ONE, 2014

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Complement-mediated neurotoxicity is regulated by homologous restriction

chi ming lee

Brain Research, 1995

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Complement gene expression and regulation in mouse retina and retinal pigment epithelium/choroid

Heping Xu

Molecular vision, 2011

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Complement-Associated Deposits in the Human Retina

Joanne Matsubara

Investigative Ophthalmology & Visual Science, 2008

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Genetic deficiency of C3 as well as CNS-targeted expression of the complement inhibitor sCrry ameliorates experimental autoimmune uveoretinitis

Suzanne Vogt

Experimental eye …, 2006

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Complement in age-related macular degeneration: a focus on function

anne hughes

Eye, 2011

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The significance of the complement system for the pathogenesis of age-related macular degeneration — current evidence and translation into clinical application

Victor Chong

Graefe's Archive for Clinical and Experimental Ophthalmology, 2010

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