Idiopathic Gingival Fibromatosis - a Case Series (original) (raw)

Idiopathic gingival fibromatosis – case report

Idiopathic gingival enlargement is a type of gingival fibromatosis characterized by progressive overgrowth of the gingival tissues.This case report presented the clinical features of a typical idiopathic gingival enlargement which was treated with external bevel gingivactomy. The patient presented with generalized diffuse gingival enlargement involving the maxillary and mandibular arches extending on buccal and lingual/palatal surfaces and covering incisal/occlusal third of the tooth resulting in difficulty in speech and mastication since last three years. Gingivectomy was carried outto improve patient's quality of life. Since removal of hyperplastic gingival tissue eliminates difficulties in eating and speaking. Therefore, this surgical intervention improves access for plaque control, and leads to psychological benefits due to esthetic improvement. In this case, even after one year from following-up, no recurrence of gingival overgrowth was observed. Keyword: Gingival Overgrowt...

An unusual case of idiopathic gingival fibromatosis

Contemporary Clinical Dentistry, 2013

Idiopathic gingival fibromatosisis, a condition of undetermined cause can develop as an isolated disorder, but mostly it is associated with some syndrome. It usually begins at the time of eruption of permanent teeth but can develop with the eruption of deciduous dentition and rarely present at birth. This case report describes an unusual case of non-syndromic generalized idiopathic gingival fibromatosis in a 15-year-old male present since birth. Surgical treatment in the form of ledge and wedge procedure with internal bevel gingivectomy was performed. No recurrence of enlargement was seen after 2 years of follow-up.

Idiopathic Gingival Fibromatosis

Journal of Indian Academy of Oral Medicine and Radiology, 2011

Idiopathic gingival fibromatosis is a rare heriditary condition characterized by slowly progressive, nonhemorrhagic, fibrous enlargement of maxillary and mandibular keratinized gingiva caused by increase in submucosal connective tissue elements. This case report gives an overview of gingival fibromatosis in a 11-year-old female patient who presented with generalized gingival enlargement. Based on the history and clinical examination, the diagnosis was made and the enlarged tissue was surgically removed. The patient was being regularly monitored clinically for improvement in her periodontal condition as well as for any recurrence of gingival overgrowth.

Idiopathic Gingival Fibromatosis -A Case Report

Idiopathic gingival fibromatosis is a rare condition. We present a case of idiopathic gingival fibromatosis with its multidisciplinary approach of management. The clinical, radiographic, and histopathological features have been described in detail.

Idiopathic Gingival Fibromatosis: Case Report and Its Management

International Journal of Dentistry, 2009

Idiopathic gingival fibromatosis is a rare condition. We present a case of idiopathic gingival fibromatosis with its multidisciplinary approach of management. The clinical, radiographic, and histopathological features have been described in detail.

Idiopathic Gingival Enlargement -A Case Report

Idiopathic gingival enlargement is a rare proliferative fibrous lesion of the keratinized gingival tissue of maxillary and mandibular arches due to increase in submucosal connective tissue elements that cause esthetic and functional problems. This case report addresses the overview of gingival fibromatosis in 17yearoldfemale. The patient presented with generalized diffuse gingival enlargement involving the maxillary and posterior teeth in mandibular arches extending on buccal and lingual/palatal surfaces of the teeth resulting in difficulty in speech and mastication since last 4-5 years. Based on the history and clinical examination, the diagnosis was made and the enlarged tissue was surgically removed.

Gingival fibromatosis: clinical, molecular and therapeutic issues

Orphanet Journal of Rare Diseases, 2016

Gingival fibromatosis is a rare and heterogeneous group of disorders that develop as slowly progressive, local or diffuse enlargements within marginal and attached gingiva or interdental papilla. In severe cases, the excess tissue may cover the crowns of the teeth, thus causing functional, esthetic, and periodontal problems, such as bone loss and bleeding, due to the presence of pseudopockets and plaque accumulation. It affects both genders equally. Hereditary, drug-induced, and idiopathic gingival overgrowth have been reported. Hereditary gingival fibromatosis can occur as an isolated condition or as part of a genetic syndrome. The pathologic manifestation of gingival fibromatosis comprises excessive accumulation of extracellular matrix proteins, of which collagen type I is the most prominent example. Mutation in the Son-of-Sevenless-1 gene has been suggested as one possible etiological cause of isolated (non-syndromic) hereditary gingival fibromatosis, but mutations in other genes are also likely to be involved, given the heterogeneity of this condition. The most attractive concept of mechanism for drug-induced gingival overgrowth is epithelial-to-mesenchymal transition, a process in which interactions between gingival cells and the extracellular matrix are weakened as epithelial cells transdifferentiate into fibrogenic fibroblast-like cells. The diagnosis is mainly made on the basis of the patient's history and clinical features, and on histopathological evaluation of affected gingiva. Early diagnosis is important, mostly to exclude oral malignancy. Differential diagnosis comprises all pathologies in the mouth with excessive gingival overgrowth. Hereditary gingival fibromatosis may present as an autosomal-dominant or less commonly autosomal-recessive mode of inheritance. If a systemic disease or syndrome is suspected, the patient is directed to a geneticist for additional clinical examination and specialized diagnostic tests. Treatments vary according to the type of overgrowth and the extent of disease progression, thus, scaling of teeth is sufficient in mild cases, while in severe cases surgical intervention is required. Prognosis is precarious and the risk of recurrence exists.

Gingival fibromatosis with multiple unusual findings: report of a rare case

Gingival fibromatosis is a rare disease, especially its syndromic form. Here, we review the literatures on gingival fibromatosis and briefly summarize some characters on clinical, etiological, genetic and histopathological aspects. We also present a rare case of gingival fibromatosis with multiple unusual findings in a 21-year-old man. And we differentiate it from some well-known syndromes including gingival fibromatosis. Maybe it implies a new syndrome within the spectrum of those including gingival fibromatosis.

17. Idiopathic_Gingival_Fibromatosis.pdf

Gingival fibromatosis (GF) is a heterogenous group of disorders characterized by progressive enlargement of the gingiva caused by an increase in submucosal connective tissue elements.