A Review on Phytopharmacological Activity of Alpinia Galanga (original) (raw)
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A REVIEW ON PHYTOPHARMACOLOGICAL ACTIVITY OF ALPINIA GALANGA Review Article
International Journal of Pharmacy and Pharmaceutical Sciences, 2019
Alpinia galanga plant which is associated with family Zingiberaceae is mainly scattered in tropical areas and widely known for ethno medicine. Against fungi and bacteria rhizome extract have a maximum inhibitory effect. Alpinia galanga plant is used in medicine and in food preparation. Rhizome extract of Alpinia galanga have high phenolic and flavonoid contents when compared to leaf extract. Because of elevated phenolic and flavonoid content in rhizome extract of Alpinia galanga there is noticeable antimicrobial as well as radical scavenging potential. It is a well-known official drug thought out the country as integrated contribution of nature. It is commonly used for the management of eczema, coryza, bronchitis, otitis interna, gastritis, ulcers, morbilli and cholera, pityriasis versicolor, to clear the mouth, emaciation. The different parts of the plant have various effects like antifungal, antiprotozoal, antiplatelet, antiviral, antidiabetic, immunomodulatory, antibacterial, anti-oxidant effects, hypolipidemic and many others. The essential oil of A. galanga identified 1, 8-cineol as a bioactive agent having antifeeding activity. An aqueous acetone extract of fruit of Alpinia galanga shows inhibitory effect on melanogenesis (formation of melanin). By using different methods, active constituent namely, 1'acetochavicol acetate in hexane extract of Alpinia galanga rhizome was investigated for their corrosion inhibition properties. The current review add significant information about its, pharmacological activities, medicinal properties and phytochemical investigations as a traditional drug to cure for a number of diseases. Every fraction of the plant has valuable properties that can deliver humanity. The complete plant will be broadly investigated for further future prospective.
A Review of an Important Medicinal Plant: Alpinia galanga (L.) Willd
Systematic Reviews in Pharmacy, 2020
Middle class people who live in rural or urban areas often find it difficult to access modern health services, so they more often use traditional medicines obtained from herbal plants that grow around them. Alpinia galanga (Zingiberaceae), often referred to as galangal, is one type of herbal plant that is widely grown in Asia. Many developing countries cultivate this plant, including Indonesia. This plant has a variety of benefits, ranging from being used as a food flavoring, which creates a distinctive aroma in cooking. This plant can also be used as a treatment for various diseases. Although the galangal rhizome is the most widely used and studied part of the plant, the flower on the galangal plant can also provide additional benefits because these flowers have antimicrobial and antioxidant properties, although their chemical composition is different from parts of the galangal rhizome. This study, therefore, aimed to describe the traditional use of rhizome galangal, its phytochemi...
Biological Activities of Greater galangal, Alpinia galanga - A Review
Green plants have been used for many years for their biological activities. Many species of Zingiberaceae family have been studied for their potential biological activity. Alpinia galanga from the family Zingiberaceae has been widely used decades ago and is still used for traditional and medicinal purposes. Easy availability and low cost has enabled more people to benefit from this dynamic plant. Studies have been conducted widely using the rhizomes, leaves, flowers, pseudostems and seeds apparently to explore its potential. Active compounds such as 1,8-cineol, α-fenchyl acetate, β-farnesene, β-bisabolene, α-bergamotene, β-pinene and 1’-acetoxychavicol acetate from Alpinia galanga plant. Among all the bioactive compounds, 1,8-cineol known as marker compound in the Alpinia spp provide strong biological activity. Active compounds from this plant cause variety of biological activities such as antibacterial, antifungal, antitumor, antiulcer, antiallergic, antioxidant effect and insecticidal activity. Therefore this is the latest information on the biological activity and the active compounds of Alpinia galanga.
ALPINIA GALANGA: AN OVERVIEW AND HERBAL INTERACTIONS
Medicinal plants and derived medicine are widely used in traditional cultures all over the world and they are becoming increasingly popular in modern society as natural alternatives to synthetic chemicals. Alpinia galanga willd. (family-zingiberaceae) commonly known as galanga, is an important cultivated medicinal crop of India. Herbal medicine consists active ingredients in crude form or as an isolated chemical constituent by various processes. Herbal medicine widely perceived by the public too, but adverse effect include important inhibition with conventional medicine occurs. The present paper is an overview on phytopharmacological properties of the plant and its herbal interactions.
International Journal of Scientific Research in Biological Sciences
Alpinia galanga and Alpinia calcarata (Zingiberaceae), are rare, fast disappearing, threatened species and well known ayurvedic herbs and are used as medicine due to anti-bronchitis, anti-inflammatory, anti-cancerous, anti-cough, antidiabetic and anti-bacterial properties. The aim of present study was to gather information for the systematic identification and authentication of these valuable species as per WHO guidelines. Powdered leaves of A.calcarata showed high alcohol soluble extractive value, high moisture content, total ash value than rhizome powder and contrary in A.galanga. On the basis of fluorescence analysis rhizomes of these species carry more active ingredients chiefly used for therapeutical purposes. The presences of alkaloids, steroids, flavonoids etc. were confirmed during preliminary phytochemical screening. The pharmacognostic characters obtained in the present investigation might be useful in drug industry for the identification, authentication and quality of commercial samples supplied by suppliers and will be very useful in designing the monograph on these drugs in the Indian Pharmacopoeia.
Antibacterial Activity of Alpinia galanga (L) Willd Crude Extracts
Applied Biochemistry and Biotechnology, 2010
Methanol, acetone and diethyl ether extracts of Alpinia galanga have been evaluated against pathogens viz. Bacillus subtilis MTCC 2391, Enterobacter aerogene, Enterobacter cloacae, Enterococcus faecalis, Escherichia coli MTCC 1563, Klebsiella pneumoniae, Pseudomonas aeruginosa MTCC 6642, Salmonella typhimurium, Staphylococcus aureus and Streptococcus epidermis using Agar well diffusion method. Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of all the extracts were determined using the macrodilution method. Methanol extracts have shown excellent activity towards all the pathogens with MIC and MBC values ranging from 0.04–1.28 mg/ml and 0.08–2.56 mg/ml, respectively. The GC–MS analysis of methanol extracts have yielded compounds like 5-hydroxymethyl furfural (59.9%), benzyl alcohol (57.6%), 1,8 cineole (15.65%), methylcinnamate (9.4%), 3-phenyl-2-butanone (8.5%) and 1,2 benzenedicarboxylic acid (8.9%), which could be responsible for its broad spectrum activity. So, A. galanga can be quite resourceful for the development of new generation drugs.
2019
Aims: Plants are invaluable sources of pharmaceutical product that have drawn the attention of ethno-pharmacologists around the world. One of the invaluable plants that has many medicinal properties since from ancient time was A. galangal. The present study aimed at investigating the antimicrobial efficacies of A. galangal against gram-positive bacteria which were S. aureus, S. epidermidis and L. monocytogenes using disc diffusion method and minimum inhibitory concentration method. Besides, this study also aimed to identify the phytochemical properties such as phenolic, flavonoid and DPPH content and to evaluate cytotoxicity level of A. galangal extracts using brine shrimp lethality test. Methodology and results: A. galangal extract exhibited antibacterial activity against all the three tested gram-positive bacterial strains. However, L. monocytogenes shows a large inhibition zone (20.62 mm) compared to S. epidermidis (18.06 mm) and S. aureus (17.25 mm). The minimum inhibitory conce...
Phenolic Compounds and Antioxidant Activities of Macerated Alpinia Galanga Stems and Leaves
ASEAN Engineering Journal, 2020
Alpinia galanga (A. galanga) is a popular culinary ingredient as well as medicinal herb commonly found in Southeast Asia. Compared to the rhizome of A. galanga, the leaves and stems are always being discarded as waste. In this research, active compounds from the stem and leaves of this plant were extracted using maceration technique with ethanol as solvent at a liquid-solid ratio of 20 ml/g. The influence of maceration time and maceration temperature on total phenolic content (TPC) and antioxidant activities of extract were studied using Folin-Ciocalteu assay and DPPH radical scavenging assay, respectively. The maceration time was from 1 to 5 hr and the maceration temperature was examined from 40 ºC to 70 ºC. Crude extract yield for stems and leaves obtained for all parameters of the maceration process was ˃11%. The highest TPC for leaves was obtained at 1 hr (0.038± 0.02 mg GAE/mg DW) and stems at 4 hr (0.024 ± 0.01 mg GAE/mg DW). Similar trend was also observed for antioxidant act...
The Potency of Alpinia galanga as Natural Antioxidant
Majalah Obat Tradisional
An antioxidant is a chemical compound that can bind free radicals in the body. Reactive oxidative species (ROS) is a reaction that involves oxygen. ROS consists of free radicals and non-radical ones. The imbalance between ROS and antioxidants can cause oxidative stress, one of the factors contributing to the development of numerous diseases. This study aims to evaluate the possible antioxidant activity of lengkuas extract (LE), which may be employed as a medicine component to reduce ROS. The method that used in this research were total phenolic content, total flavonoid content, 2,2 diphenyl 1 picrylhydrazyl (DPPH) scavenging, hydrogen peroxide (H2O2), NO scavenging, 2,2′-Azinobis(3-Ethylbenzthiazoline-6-Sulfonate) (ABTS), and ferric reducing antioxidant power (FRAP). The result shows that the TPC of LE was 6.80 ± 0.34 (GAE) µg/mg with gallic acid standard and the TFC was 3.39 ± 0.06 µg/mg by quercetin standard. The IC50 value of LE were 121.20; 87.65; 139.94; 181.09 µg/ml by ABTS, D...