Influence of HAP on the Morpho-Structural Properties and Corrosion Resistance of ZrO2-Based Composites for Biomedical Applications (original) (raw)
Related papers
2020
In the present work, zirconia-based biocomposites were prepared by adding different amounts of antibacterial magnesium oxide and bioactive and biocompatible hydroxyapatite (HAP). The biocomposites were synthesized by the conventional ceramic processing route. The structure and morphology of the materials were investigated using X-ray powder diffraction (XRPD), scanning and transmission electronic microscopy (SEM and TEM). The stability of the tetragonal structure of ZrO2 was confirmed by XRPD analyses. Moreover, their bioactivity was studied by soaking the samples in artificial saliva (AS) to evaluate the effect of MgO and HAP on the biological performances of the prepared biocomposites. UV-VIS analyses carried out on artificial saliva after immersion of the prepared materials showed that MgO plays an important role in the post-immersion dissolution process.
Applied Surface Science, 2016
The degradation characteristics of hydroxyapatite-zirconia-silver films (HA-ZrO2-Ag) coatings on three ZrTi alloys were investigated in Ringer's solution containing 10% human albumin protein at 37 °C. Samples were immersed for 7 days while monitored by electrochemical impedance spectroscopy (EIS) and linear potentiodynamic polarization (LPP). The electrochemical analysis in combination with surface analytical characterization by scanning electron microscopy (SEM/EDX) reveals the stability and corrosion resistance of the HA-ZrO2-Ag coated ZrTi alloys. The characteristic feature that describes the electrochemical behaviour of the coated alloys is the coexistence of large areas of the coating presenting pores in which the ZrTi alloy substrate is exposed to the simulated physiological environment. The EIS interpretation of results was thus performed using a two-layer model of the surface film. The blocking effect in the presence the human albumin protein produces an enhancement of the corrosion resistance. The results disclose that the Zr45Ti alloy is a promising material for biomedical devices, since electrochemical stability is directly associated to biocompatibility.
BioMed Research International, 2014
The surface characteristics of implant which influence the speed and strength of osseointegration include surface chemistry, crystal structure and crystallinity, roughness, strain hardening, and presence of impurities. The aim of this study was to evaluate the bioactivity and roughness of a novel natural hydroxyapatite/zircon (NHA/zircon) nanobiocomposite, coated on 316L stainless steel (SS) soaked in simulated body fluid (SBF). NHA/zircon nanobiocomposite was fabricated with 0 wt.%, 5 wt.%, 10 wt.%, and 15 wt.% of zircon in NHA using ball mill for 20 minutes. The composite mixture was coated on 316L SS using plasma spray method. The results are estimated using the scanning electron microscopy (SEM) observation to evaluate surface morphology, X-ray diffraction (XRD) to analyze phase composition, and transmission electron microscopy (TEM) technique to evaluate the shape and size of prepared NHA. Surfaces roughness tester was performed to characterize the coated nanocomposite samples. The maximum average (14.54 m) was found in the NHA 10 wt.% of zircon coating. In addition, crystallinity ( ) was measured by XRD data, which indicated the minimum value ( = 41.1%) for the sample containing 10 wt.% of zircon. Maximum bioactivity occurred in the sample containing 10 wt.% of zircon, which was due to two reasons: first, the maximum roughness and, second, the minimum crystallinity of nanobiocomposite coating.
Turkiye Klinikleri Journal of Dental Sciences, 2020
Zirconia is used as a dental implant material due to its high resistance, biocompatibility, and the success of osseointegration. 1 Nowadays, zirconia dental implants are used as an alternative to titanium alloy implants for their aesthetic and biochemical properties. 2-5 The characteristic of the bone-contacting surface of the implant, as well as the raw material, directly affects the success of osseointegration. 6 Many physical and chemical methods facilitate implant surface preparation. Plasma spray coating method using biocompatible materials has recently become popular. This method supports the potential of osseointegration by allowing the implant to be coated with various biocompatible powders (ceramics, metals, etc.) to prevent oxidation, corrosion and to ensure heat resistance. 7
Electrochimica Acta, 2015
Mg alloys are very susceptible to corrosion in physiological media. This behaviour limits its widespread use in biomedical applications as bioresorbable implants, but it can be controlled by applying protective coatings. On one hand, coatings must delay and control the degradation process of the bare alloy and, on the other hand, they must be functional and biocompatible. In this study a biocompatible polycaprolactone (PCL) coating was functionalised with nano hydroxyapatite (HA) particles for enhanced biocompatibility and with an antibiotic, cephalexin, for anti-bacterial purposes and applied on the AZ31 alloy. The chemical composition and the surface morphology of the coated samples, before and after the corrosion tests, were studied by scanning electron microscopy (SEM) coupled with energy dispersive x-ray analysis (EDX) and Raman. The results showed that the presence of additives induced the formation of agglomerates and defects in the coating that resulted in the formation of pores during immersion in Hanks' solution. The corrosion resistance of the coated samples was studied in Hank's solution by electrochemical impedance spectroscopy (EIS). The results evidenced that all the coatings can provide corrosion protection of the bare alloy. However, in the presence of the additives, corrosion protection decreased. The wetting behaviour of the coating was evaluated by the static contact angle method and it was found that the presence of both hydroxyapatite and cephalexin increased the hydrophilic behaviour of the surface. The results showed that it is possible to tailor a composite coating that can store an antibiotic and nano hydroxyapatite particles, while allowing to control the in-vitro corrosion degradation of the bioresorbable Mg alloy AZ31.
INTERNATIONAL CONFERENCE ON BIOLOGY AND APPLIED SCIENCE (ICOBAS), 2019
The developmental of composites as dental coating materials is growing rapidly. To increase mechanical, physical and aesthetical properties of dental coating materials, has been developed composited dental based on ceramic matrix composites. Only a few ceramic biomaterials that are suitable for this dentistry i.e. zirconia (ZrO2) and alumina (Al2O3). Zirconia and alumina-based ceramic present interesting properties for their application such as a dental coating material. Zirconia was used as the matrix, extracted from natural zircon sands Kereng Pangi, Central Kalimantan and alumina powder were used as the filler. In this work, influence of ZrO2composition on ZrO2/Al2O3 ceramic composites that using 100, 70, 60weight% zirconia was characterized. Powder of ZrO2 and Al2O3 were mixture by planetary ball milling for 3h at 150rpm. Homogeneous of composites can be affected from speed and duration of stirring. The homogeneous of filler and matrix can be improved mechanical properties of composites. Powder mixtures were pressed under 80MPa pressure. Characterization FTIR and XRD were used to confirm the absence of any new phase and the composites were formed. The FTIR analysis showed that no new compounds are formed between ZrO2 and Al2O3. This result can be correlated with the XRD pattern of ZrO2/Al2O3.
Materials Science and Engineering: C, 2015
Enhanced coating stability and adhesion are essential for long-term success of orthopedic and dental implants. In this study, the effect of coating composition on mechanical, physico-chemical and biological properties of coated zirconia specimens is investigated. Zirconia discs and dental screw implants are coated using the wet powder spraying (WPS) technique. The coatings are obtained by mixing yttria-stabilized zirconia (TZ) and hydroxyapatite (HA) in various ratios while a pure HA coating served as reference material. Scanning electron microscopy (SEM) and optical profilometer analysis confirm a similar coating morphology and roughness for all studied coatings, whereas the coating stability can be tailored with composition and is probed by insertion and dissections experiments in bovine bone with coated zirconia screw implants. An increasing content of calcium phosphate (CP) resulted in a decrease of mechanical and chemical stability, while the bioactivity increased in simulated body fluid (SBF). In vitro experiments with human osteoblast cells (HOB) revealed that the cells grew well on all samples but are affected by dissolution behavior of the studied coatings. This work demonstrates the overall good mechanical strength, the excellent interfacial bonding and the bioactivity potential of coatings with higher TZ contents, which provide a highly interesting coating for dental implants.
Materials, 2017
Zirconia (ZrO 2) and zirconia-based glasses and ceramics are materials proposed for use in the dental and orthopedic fields. In this work, ZrO 2 glass was modified by adding different amounts of bioactive and biocompatible hydroxyapatite (HAp). ZrO 2 /HAp composites were synthesized via the sol-gel method and heated to different temperatures to induce modifications of their chemical structure, as ascertained by Fourier transform infrared spectroscopy (FTIR) analysis. The aim was to investigate the effect of both HAp content and heating on the biological performances of ZrO 2. The materials' bioactivity was studied by soaking samples in a simulated body fluid (SBF). FTIR and scanning electron microscopy (SEM)) analyses carried out after exposure to SBF showed that all materials are bioactive, i.e., they are able to form a hydroxyapatite layer on their surface. Moreover, the samples were soaked in a solution containing bovine serum albumin (BSA). FTIR analysis proved that the synthesized materials are able to adsorb the blood protein, the first step of cell adhesion. WST-8 ([2-(2-methoxy-4-nitrophenyl)-3-(4-nitrophenyl)-5-(2,4-disulfophenyl)-2H-tetrazolium, monosodium salt]) assay showed that no cytotoxicity effects were induced by the materials' extract. However, the results proved that bioactivity increases with both the HAp content and the temperature used for the thermal treatment, whereas biocompatibility increases with heating but is not affected by the HAp content.
Materials
Zirconia is a well-known bioceramic for dental and orthopedic applications due to its mechanical and aesthetic properties. However, it lacks sufficient bioactivity to bond with the living bone. This study was aimed to induce bioactivity to tetragonal zirconia polycrystal (3Y-TZP) by simple biomimetic aqueous solution treatment. First, hydrofluoric acid (HF) etching was performed to enhance the surface roughness of the 3Y-TZP surface. Then, the samples were treated with two types of aqueous solutions containing calcium and phosphate ions (Ca-P solutions); one solution additionally contained magnesium (Mg) ions and the other without Mg ions. Finally, hydroxyapatite (HAp)-forming ability was evaluated by the conventional simulated body fluid (SBF) test, and the effect of Mg ions on the adhesive strength of the HAp layer to the roughened 3Y-TZP surface was also investigated. The results concluded that there were no noticeable differences in the effect of Mg ions on the HAp-forming abili...
Zirconia based dental ceramics: structure, mechanical properties, biocompatibility and applications
Zirconia (ZrO 2) based dental ceramics have been considered to be advantageous materials with adequate mechanical properties for the manufacturing of medical devices. Due to its very high compression strength of 2000 MPa, ZrO 2 can resist differing mechanical environments. During the crack propagation on the application of stress on the surface of ZrO 2 , a crystalline modification diminishes the propagation of cracks. In addition, zirconia's biocompatibility has been studied in vivo, leading to the observation of no adverse response upon the insertion of ZrO 2 samples into the bone or muscle. In vitro experimentation has exhibited the absence of mutations and good viability of cells cultured on this material leading to the use of ZrO 2 in the manufacturing of hip head prostheses. The mechanical properties of zirconia fixed partial dentures (FPDs) have proven to be superior to other ceramic/composite restorations and hence leading to their significant applications in implant supported rehabilitations. Recent developments were focused on the synthesis of zirconia based dental materials. More recently, zirconia has been introduced in prosthetic dentistry for the fabrication of crowns and fixed partial dentures in combination with computer aided design/computer aided manufacturing (CAD/CAM) techniques. This systematic review covers the results of past as well as recent scientific studies on the properties of zirconia based ceramics such as their specific compositions, microstructures, mechanical strength, biocompatibility and other applications in dentistry.