Mechanistic role of cytochrome P450 (CYP)1B1 in oxygen-mediated toxicity in pulmonary cells: A novel target for prevention of hyperoxic lung injury (original) (raw)

Mice deficient in the gene for cytochrome P450 (CYP)1A1 are more susceptible than wild-type to hyperoxic lung injury: evidence for protective role of CYP1A1 against oxidative stress

Xanthi Couroucli

Toxicological sciences : an official journal of the Society of Toxicology, 2014

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Augmented oxygen-mediated transcriptional activation of cytochrome P450 (CYP)1A expression and increased susceptibilities to hyperoxic lung injury in transgenic mice carrying the human CYP1A1 or mouse 1A2 promoter in vivo

Roberto Barrios

Biochemical and Biophysical Research Communications, 2011

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Hyperoxia-mediated transcriptional activation of cytochrome P4501A1 (CYP1A1) and decreased susceptibility to oxygen-mediated lung injury in newborn mice

Xanthi Couroucli

Biochemical and Biophysical Research Communications, 2018

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Disruption of Cytochrome P4501A2 in mice leads to increased susceptibility to hyperoxic lung injury

Xanthi Couroucli

Free radical biology & medicine, 2015

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Regulation of cytochrome P4501A1 expression by hyperoxia in human lung cell lines: Implications for hyperoxic lung injury

Kushal Bhakta

Toxicology and Applied Pharmacology, 2008

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The role of cytochrome P450 (CYP) enzymes in hyperoxic lung injury

Xanthi Couroucli

Expert Opinion on Drug Metabolism & Toxicology, 2020

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Role of Cytochrome P450 (CYP)1A in Hyperoxic Lung Injury: Analysis of the Transcriptome and Proteome

Xanthi Couroucli

Scientific reports, 2017

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Modulation of Pulmonary Cytochrome P4501A1 Expression by Hyperoxia and Inhaled Nitric Oxide in the Newborn Rat: Implications for Lung Injury

Lee Evey, Roberto Barrios

Pediatric Research, 2006

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Attenuation of Hyperoxic Lung Injury by the CYP1A Inducer -Naphthoflavone

Roberto Barrios

Toxicological Sciences, 2005

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Attenuation of Hyperoxic Lung Injury by the CYP1A Inducer β–Naphthoflavone

Xanthi Couroucli

Toxicological Sciences, 2005

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Disruption of the Ah Receptor Gene Alters the Susceptibility of Mice to Oxygen-Mediated Regulation of Pulmonary and Hepatic Cytochromes P4501A Expression and Exacerbates Hyperoxic Lung Injury

Roberto Barrios

Journal of Pharmacology and Experimental Therapeutics, 2004

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Signal Transduction Pathways in Hyperoxia-Induced Lung Cell Death

Lin Mantell

Molecular Genetics and Metabolism, 2000

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Effects of hyperoxic exposure on signal transduction pathways in the lung

Camillo Di Giulio

Respiratory Physiology & Neurobiology, 2015

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Reactive Oxygen Species and Extracellular Signal-Regulated Kinase 1/2 Mitogen-Activated Protein Kinase Mediate Hyperoxia-Induced Cell Death in Lung Epithelium

Xuchen Zhang

American Journal of Respiratory Cell and Molecular Biology, 2003

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Hyperoxia Inhibits Oxidant-induced Apoptosis in Lung Epithelial Cells

Lin Mantell

Journal of Biological Chemistry, 2001

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NADPH Oxidase-1 Plays a Crucial Role in Hyperoxia-induced Acute Lung Injury in Mice

Constance Barazzone-Argiroffo

American Journal of Respiratory and Critical Care Medicine, 2009

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Hypoxia Protects Human Lung Microvascular Endothelial and Epithelial-like Cells against Oxygen Toxicity

Aftab Ahmad

American Journal of Respiratory Cell and Molecular Biology, 2003

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Hyperoxia-induced signal transduction pathways in pulmonary epithelial cells☆

Dympna Morrow, Lin Mantell

Free Radical Biology and Medicine, 2007

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doi:10.1155/2011/260482 Review Article Consequences of Hyperoxia and the Toxicity of Oxygen in the Lung

Amanda Thimmesch

2013

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Hyperoxia causes angiopoietin 2–mediated acute lung injury and necrotic cell death

Vineet Bhandari

Nature Medicine, 2006

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Hyperoxia-induced Cell Death in the Lung-the Correlation of Apoptosis, Necrosis, and Inflammation

Lin Mantell

Annals of The New York Academy of Sciences, 2006

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Newborn mice lacking the gene for Cyp1a1 are more susceptible to oxygen-mediated lung injury, and are rescued by postnatal β-napthoflavone (BNF) administration: Implications for bronchopulmonary dysplasia (BPD) in premature infants

Xanthi Couroucli

Toxicological sciences : an official journal of the Society of Toxicology, 2017

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Consequences of Hyperoxia and the Toxicity of Oxygen in the Lung

Amanda Thimmesch

Nursing Research and Practice, 2011

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Prenatal administration of the cytochrome P4501A inducer, Β-naphthoflavone (BNF), attenuates hyperoxic lung injury in newborn mice: Implications for bronchopulmonary dysplasia (BPD) in premature infants

Roberto Barrios

Toxicology and Applied Pharmacology, 2011

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Gene Expression Profile of Human Airway Epithelium Induced by Hyperoxia In Vivo

Arnaud Chambellan

American Journal of Respiratory Cell and Molecular Biology, 2006

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CYP1A2 protects against reactive oxygen production in mouse liver microsomes

Corey Clay

Free Radical Biology and Medicine, 2004

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Molecular role of cytochrome P4501A enzymes in oxidative stress

Xanthi Couroucli

Current Opinion in Toxicology, 2020

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Bcl-2 Family Gene Expression during Severe Hyperoxia Induced Lung Injury

Richard Watkins

Laboratory Investigation, 2000

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CYP1B1 and endothelial nitric oxide synthase combine to sustain proangiogenic functions of endothelial cells under hyperoxic stress

Nader Sheibani

American Journal of Physiology-cell Physiology, 2010

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Heat Shock Protein 27 Protects Lung Epithelial Cells From Hyperoxia-Induced Apoptotic Cell Death

William Gerthoffer

Pediatric Research, 2009

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