Effectiveness and Safety of Sclerotherapy for Treatment of Low-Flow Vascular Malformations of the Oropharyngeal Region (original) (raw)
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Journal of Natural Science, Biology and Medicine, 2012
Vascular anomalies constitute some of the most difficult diagnostic and therapeutic enigmas in the head and neck region. It is of paramount importance that a modern classification system is established to differentiate vascular lesions from vascular malformations. Vascular malformations are usually congenital and venous anomalies usually expand because of hormonal changes such as puberty, pregnancy, or secondary to trauma. Here, we report a case which was diagnosed as low flow vascular malformation of buccal mucosa involving the lower lip and subsequently treated with 3% sodium tetra decyl sulfate. This paper provides overall understanding regarding the presentation and management of small vascular lesions in the orofacial region. Percutaneous sodium tetradecyl sulfate when used either alone or as adjunct to surgery is a safe, effective, and inexpensive agent in the treatment of venous malformations. However, proper case selection, evaluation, and careful planning are necessary to reduce the unwarranted risks and complications.
STS Sclerotherapy in the Treatment of Vascular Malformation of Tongue- a Case Report
2009
Dr. Adhiraj Ghosh Second Year MDS PGT Department of Oral & Maxillofacial Surgery Haldia Institute of Dental Sciences and Research Haldia, West Bengal CORRESPONDING AUTHOR INTRODUCTION:Vascular malformations in the head and neck region present a difficult managementchallenge.The first line treatment for most venous malformations (VMs) and s o m e l y m p h a t i c m a l f o r m a t i o n s i s Sclerotherapy. Injection sclerotherapy using STS offers an effective treatment option when managing patients presenting with venous malformations (VM) in the oral cavity. A single treatment may be adequate for small lesions but the procedure may be safely repeated until a satisfactory result is obtained.Here we present a case report of venous malformation at the tip o f t h e t o n g u e w i t h 3 % s o d i u m tetradecylsulphate (STS) and describe our experience.
Erciyes Medical Journal, 2017
Objective: Percutaneous ethanol sclerotherapy has shown to be efficient in treating venous malformations of the head and neck. Our aim was to assess the safety and efficacy of percutaneous ethanol sclerotherapy in treating venous malformations of the oral cavity and the oropharynx. Materials and Methods: From 2007 to 2015, 57 percutaneous procedures using ethanol were performed in 13 patients. Medical records of these patients were retrospectively analyzed. One patient was male and 12 were females. The patients' age ranged from 8 to 65 years (mean age, 30 years). The mean follow-up was 11 months. The volume of ethanol used per session ranged from 0.4 to 14 mL (mean volume, 6 mL) in 12 patients, except the syndromic patient. Results: In 7 out of 13 patients (53.4%), the lesions were resolved completely. In 3 patients (23%), sclerotherapy alleviated the symptoms. In 2 patients (15.3%), the lesions did not sufficiently respond to the therapy. In 1 patient (7.6%), sclerother-apy failed due to misdiagnosis. No major complications were encountered. All the patients experienced pain to a tolerable degree. Swelling, induration, and darkening of the lesion occurred following injections. In 1 patient, ulceration and cleavage on the tongue was resolved within 15 days after emergence. Conclusion: Percutaneous ethanol sclerotherapy is a reliable and efficacious method of treating venous malformations of the oral cavity and oropharynx.
Journal of Clinical Interventional Radiology ISVIR, 2018
Purpose To study the safety and effectiveness of sclerotherapy with 3% sodium tetradecyl sulfate (STS) in the management of venous malformation (VM) of the tongue. Materials and Methods The clinical and imaging data of patients with tongue VM treated with STS sclerotherapy over a period of 15 years (2002–2017) were reviewed. Safety was assessed based on the incidence of minor and major complications. Effectiveness was assessed by clinical improvement (reduction in symptoms and size) on a 10-point scale. Results The study included 44 patients (26 men and 18 women). The median age was 24 years at the time of treatment. Eight patients were lost to follow-up. Four patients (4 of 44, 9%) had complications including venous bleeding needing compression, self-limiting hematuria, significant swelling of the tongue requiring prolonged intubation, and arterial bleeding due to injury to the lingual artery. Clinical improvement was seen in 30 (30 of 36, 83%). The median clinical improvement was ...
Percutaneous ethanol sclerotherapy of venous malformations of the tongue
American Journal of Neuroradiology
Percutaneous ethanol sclerotherapy has been reported to be efficacious for head and neck venous malformations. We sought to evaluate the safety and efficacy of percutaneous sclerotherapy by using ethanol for treatment of symptomatic venous malformations of the tongue. Eleven sclerotherapy procedures were performed in seven patients from January 1995 to February 2001. Patient age ranged from 19 months to 57 years (mean age, 32 years). Four patients were male and three were female. Mean follow-up was 36 months. The volume of ethanol used per treatment session ranged from 2 to 32 cc (mean, 16 cc). Sclerotherapy provided significant improvement or resolution of symptoms for all patients. There were no major complications. One patient had a small (3 x 2 cm) area of skin blistering at the injection site. All patients experienced pain and swelling to a variable degree. Sclerotherapy resulted in resolution of symptoms in six of seven patients. Three patients had resolution of symptoms after...
Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2015
OBJECTIVE To assess and compare the effectiveness of the two sclerosing agents (95% alcohol and Bleomycin) for the treatment of head and neck venous malformation (VM). MATERIAL AND METHOD The authors retrospectively reviewed our experience in treating VM of the head and neck region using two sclerosing agents, 95% alcohol (November 2001 to June 2008) and bleomycin (July 2008 to July 2010). Patients' demography (age, sex), lesion number location, type (focal/extensive), and characteristic features (cystic/tubular/mixed) were recorded. The treatment outcome was determined by decrease in size of VM in photographs taken at one month and at final clinical follow-up. These were analyzed by two radiologists using visual rating scale (worst or not improved, <50%, 50-75%, >75% of size reduction). One-way Anova test (p < 0.1) was used to show the differences in treatment effectiveness of the two sclerosing agents at short- and long-term intervals. RESULTS Thirty-three patients, a...
Journal of Plastic, Reconstructive & Aesthetic Surgery, 2019
Background: Many treatment options for venous malformations (VMs) have been documented in the literature, but injection sclerotherapy has been considered a current mainstay for their treatment. We conducted this study to determine the efficacy and durability of injection of different forms of bleomycin sclerotherapy in the treatment of VMs in the cervicofacial region. Patients and Methods: Thirty patients with clinically diagnosed VMs of the head and neck region, confirmed by magnetic resonance imaging, had been injected with the bleomycin sclerosing material. They were divided into 2 groups according to the form of bleomycin injected: in Group A, the foam form was injected, and in Group B, the liquid form was injected. Data of patients' demographics, anatomical sites, type and volume of the VMs, number of injection sessions and the average dose of injected agents were documented and statistically compared between the 2 groups. Results: MRI showed a decline of more than 90% from the initial size of the lesions in 66.7% of the cases and considerable decline (60-90%) in 33.3% of the cases. In Group A, the number of sessions and the amount of sclerosant material injected were lower than those in Group B. The cumulative dose in the equal-sized lesions was lower in the foam form than in the liquid form. Conclusion: We recommend using bleomycin in its foam form on a greater number of patients with larger VMs and in different sites, as the results are more promising in this form than in the liquid form.