Pattern of Nonmelanoma Skin Cancers in Sikkim, India: A 3-year Clinicopathological Review (original) (raw)
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Journal of skin cancer, 2014
Objectives. Although the incidence of skin cancers in India (part of South Asia) is low, the absolute number of cases may be significant due to large population. The existing literature on BCC in India is scant. So, this study was done focusing on its epidemiology, risk factors, and clinicopathological aspects. Methods. A hospital based cross-sectional study was conducted in Punjab, North India, from 2011 to 2013. History, examination and histopathological confirmation were done in all the patients visiting skin department with suspected lesions. Results. Out of 36 confirmed cases, 63.9% were females with mean ± SD age being 60.9 ± 14.2 years. Mean duration of disease was 4.7 years. Though there was statistically significant higher sun exposure in males compared to females (P value being 0.000), BCC was commoner in females, explainable by intermittent sun exposure (during household work in the open kitchens) in women. Majority of patients (88.9%) had a single lesion. Head and neck r...
Clinicopathological study of basal cell carcinoma over a period of nine years-from Uttar Pradesh
IP Innovative Publication Pvt. Ltd., 2018
Introduction: Basal cell carcinoma is the most common type of skin cancer and occurs mostly in the head and neck region in middle age to elderly people. It has varied clinical presentation and also many morphologic/histopathologic subtypes. Aim of the Study: To study the spectrum of basal cell carcinomas in our institute over a nine year period. Materials and Methods: This was a prospective study carried out at Subharti Medical College, Meerut, Uttar Pradesh, over a period of nine years. All the basal cell carcinomas reported during this period were studied for clinical presentation, demographic details, anatomical location of tumor, macroscopic and microscopic appearance. Results: A total of 28 cases of BCC were reported. The patient age ranged from 14 to 85 years and the male to female ratio was 2.1:1. Most of the cases occurred over 40 years and all the tumors occurred in the facial region. Clinically, ulcerative and nodular presentation was more common. One case of nevoid BCC syndrome was also seen. Conclusion: Basal cell carcinoma commonly occurs in the face region and its incidence increases with advancing age. It has varied clinical presentations and histologic subtypes. Early diagnosis gives better prognosis. Basal cell carcinoma in a young person or child should be evaluated for nevoid BCC syndrome. Keywords: Basal cell carcinoma, Histologic subtypes of BCC, Nevoid BCC syndrome.
Journal of Evolution of Medical and Dental Sciences, 2017
BACKGROUND Basal Cell Carcinomas (BCC) are the most common amongst the non-melanoma skin cancers. The existing literatures on BCC are scant in India. BCC are rare in dark skin, because of the inherent photoprotection of melanin and melanosomal dispersion. Risk factors include UV light exposure, ionising radiation, exposure to arsenic, mutations. Although, BCCs have excellent prognosis, if left untreated it causes significant disfigurement and invasion of surrounding tissues. The present study was aimed to evaluate the risk factors, clinical and histopathological spectrum of BCC in Eastern Andhra Pradesh. The objectives were to analyse clinical data with respect to age, sex, occupation, sunlight exposure, anatomical location, size of the lesion, morphological and histopathological subtypes. MATERIALS AND METHODS The present study was conducted in DVL Department, Rangaraya Medical College, Kakinada, Andhra Pradesh. A prospective analysis of 40 cases of BCC in a period of 3 years: January 2014-December 2016 diagnosed and confirmed histopathologically. RESULTS Out of 40 cases, 65% were females. History of exposure to the sunlight was observed in all the cases. One case of 18-year-old female with xeroderma pigmentosum with BCC was seen. Sites noted were forehead (22.5%), ear, nose and infraorbital region (each 15%). Clinically, pigmentation was evident in 19 cases. Morphological types seen were ulcerative (55%), nodular (37.5%), swelling/cyst (5%) and morpheaform (2.5%). Histological types are nodular (57.5%), pigmented (25%), adenoid (7.5%), keratotic (2.5%) and with sebaceous differentiation (2.5%). Recurrent BCCs were seen in two cases. CONCLUSION This study highlights the role of sunlight and farming as aetiological risk factors of BCC and female preponderance. Forehead is the common site of presentation. Nodular and pigmented types (subtype of nodular variant) were common. Early detection of BCC lesions, particularly of small size (< 2 cm) helps in preventing further recurrences.
Study of Basal Cell Carcinoma and Its Morphological Spectrum
2019
Original Research Article Introduction: Basal cell carcinoma is the most common skin malignancy worldwide with a predilection towards sun exposed areas especially head and neck areas. It is a slow growing tumour with propensity for local invasion, however metastasis is seldom seen. The histopathological variants seen in BCC are nodular, micronodular, cystic, superficial, pigmented, adenoid, infiltrating, sclerosing, keratotic, infundibulocystic, metatypical, basosquamous etc. Aim: The aim was to study morphological spectrum of BCC cases in a tertiary care hospital in southern region of New Delhi. Materials and Methods: This study was a retrospective analysis in which nine cases of BCCs were included. Result: The mean age of presentation was 68.4 years. There was female preponderance (77%). Face was the most common location (88%) with cheek being the commonest and the ulceration was the most common clinical presentation (66.6%). Among the nine cases of BCC’s, 33.3% were solid, 22.2% ...
Anais Brasileiros de Dermatologia, 2012
BACKGROUND: Non-melanoma skin cancer, a common designation for both basal cell carcinomas and squamous cell carcinomas, is the most frequent malignant skin neoplasm. OBJECTIVE: Epidemiologic characterization of the population with Non-melanoma skin cancer. METHODS: Retrospective analysis of all patients diagnosed with Non-melanoma skin cancer based on histopathologic analysis of all incisional or excisional skin biopsies performed between 2004 and 2008 in a Department of Dermatology. RESULTS: A total of 3075 Non-melanoma skin cancers were identified, representing 88% of all malignant skin neoplasms (n=3493) diagnosed in the same period. Of those, 68,3% were basal cell carcinomas. Most Non-melanoma skin cancer patients were female and over 60 years old. Of all Non-melanoma skin cancer, 81,7% (n=1443) were located in sun-exposed skin, and represented 95,1% of malignant skin neoplasms in sun-exposed skin. Non-melanoma skin cancer was the most frequent malignant skin neoplasm in most to...
Journal of Pharmaceutical Research International, 2022
Background: Skin malignancies are more common in fair-skinned persons, but their increasing incidence is alarming in our population. Objective: To evaluate the Basal Cell Carcinoma (BCC) in a tertiary care center, in terms of frequency, age, sex, sites, and histological subtypes. Methods: A retrospective work was conducted in the Dermatology and Pathology departments, Peoples University of Medical & Health Sciences, Nawabshah, from November 2020 to November 2021, total 100 cases collected by nonprobability consecutive technique, all the patients included reported at the outpatient department during one year period. All the clinical demographic data was collected in the Dermatology department and the biopsy sample was processed in the Pathology department. The observations were recorded on a structured proforma, statistically analyzed on SPSS 20 and the results were tabulated. Results: A total of 100 cases were assessed, the age of patients ranged from 22-86 years with a female prepo...
FREQUENCY DISTRIBUTION OF BASALIOMA SKIN CANCER AT DR. MOEWARDI HOSPITAL, SURAKARTA, CENTRAL JAVA
The 8th International Conference on Public Health Solo, Indonesia, November 17-18, 2021 | 1149, 2021
Background: Basalioma is a nonmelanoma skin cancer that grows from the basal epidermal cells. It commonly occurs in the head and neck area exposed to ultraviolet light (UV). Data in Dr. Moewardi hospital 2013-2015 showed that basalioma was the most common type of skin cancer. This study aimed to describe the basalioma skin cancer in Dr. Moewardi hospital, Surakarta. Subjects and Method: This cross-sectional study was conducted at Dr. Moewardi Hospital, Surakarta, Central Java, from 2016 to 2019. A sample of 70 patients diagnosed with basalioma skin cancer was selected for this study. The study variables were gender, age, occupation, tumor location, tumor size, and clinical tumor type. The data were collected from the medical record. The data were described in percent. Results: As many as 64.3% of basalioma patients were female, 30% were farmers, 90.02% aged ≥50 years, 72% had tumors located in the midface region, 70% had a tumor in the H-zone, 72.8% had tumor size <2 cm, and 58.5% had a nodular tumor. Conclusion: The frequency distribution of basalioma in Dr. Moewardi Hospital has been described by gender, age, tumor location, tumor size, and histopathological type.
Dermatology Reports
Background: Basal cell carcinoma (BCC) is the most common skin cancer with globally increasing incidence. To date, the information regarding BCC in Thailand is limited.Objective: To evaluate the demographic, clinical, histopathological trends of BCC and other contributing factors.Methods: We retrospectively reviewed the demographic, clinical and histological data of all BCC outpatients from January 2009 to December 2018.Results: From 278 BCC patients recruited to this study, most of them (71.6%) were older than 60 years old. The most common histological subtype was nodular BCC (63.3%). A statistically significant association was observed between histological variant and location of the tumor; H and M area were associated with nodular BCC, L area was related to superficial subtype (p-value < 0.001). Misdiagnosis of BCC was observed in 53 cases, mostly as melanocytic nevus (30.2%), and about quarter (26.4%) was made by board-certified dermatologists.Conclusions: Nodular BCC is sign...
Clinical and Experimental Dermatology
Background Literature on the dermoscopic patterns of basal cell carcinoma (BCC) in India is limited. Aim To describe the dermoscopic pattern and dermoscopic–histopathological correlation in a large cohort of patients with BCC from India, with a particular focus on skin of colour (SOC). Methods This retrospective study was conducted under the aegis of the Dermatoscopy Society of India. Clinical details were collected, and two lead authors independently analysed dermoscopic images of BCC for a predefined set of characteristics. Histopathological slides/blocks were reviewed, and dermoscopic–histological correlation attempted. Results In total, 143 patients with BCC and skin phototypes IV–VI were included. The mean largest BCC diameter was 3.10 ± 3.68 cm and there was a significant but weak association between duration and largest dimension of the lesion (Spearman ρ = 0.33, P < 0.01). Nearly half of the cases were diagnosed with pigmented BCC and the most common histological subtype ...