The 42nd Symposium Chromatographic Methods of Investigating Organic Compounds : Book of abstracts (original) (raw)
Related papers
Pure and Applied Chemistry, 1994
Names of countries given after Members' names are in accordance with the IUPAC Handbook 1991-93; changes will be effected in the 1994-95 edition. Republication of this report is permitted without the need for formal IUPAC permission on condition that an acknowledgement, with full reference together with IUPAC copyright symbol (0 1994 IUPAC), is printed. Publication of a translation into another language is subject to the additional condition of prior approval from the relevant IUPAC National Adhering Organization. Analytical techniques for trace organic compounds-Vl: Application of liquid chromatography-mass spectrometry (
Principles of organic chemistry
This book and the individual contributions contained in it are protected under copyright by the Publisher (other than as may be noted herein). Notices Knowledge and best practice in this field are constantly changing. As new research and experience broaden our understanding, changes in research methods, professional practices, or medical treatment may become necessary. Practitioners and researchers must always rely on their own experience and knowledge in evaluating and using any information, methods, compounds, or experiments described herein. In using such information or methods they should be mindful of their own safety and the safety of others, including parties for whom they have a professional responsibility.
Contents lists available at SciVerse ScienceDirect Journal of Chromatography A
A residue analysis method for the simultaneous estimation of 349 pesticides, 11 PCBs and 15 PAHs extracted from grape, pomegranate, okra, tomato and onion matrices, was established by using a gas chromatograph coupled to an electron impact ionization triple quadrupole mass spectrometer (GC-EI-MS/MS). The samples were extracted by ethyl acetate and cleaned by dispersive solid phase extraction with PSA and/or GCB/C 18 by the methods reported earlier. The GC-EI-MS/MS parameters were optimized for analysis of all the 375 compounds within a 40 min run time with limit of quantification for most of the compounds at <10 g/L, which is well below their respective European Union-Maximum Residue Levels. The coefficient of determination (r 2 ) was >0.99 within the calibration linearity range of <5-250 ng/mL for compounds with LOQs < 5 ng/mL. While for the compounds with LOQs within 5-10 g/kg, the lowest calibration level was 5 and 10 g/kg as applicable. The recoveries at 10, 25 and 50 ng/mL were within 70-110% (n = 6) with associated RSDs < 20% indicating satisfactory precision. The information generated from the single laboratory validation was further utilized for building a semi-quantitative approach. The accuracies in quantification obtained via individual calibration standards vis-à-vis semiquantification approach were comparable. For incurred samples, the concentrations estimated by the semi-quantification approach were within ±10% of the values obtained by direct quantification. This approach complements the existing GC-EI-MS/MS methods by offering targeted screening and quantification capabilities.
An Open Letter to the Community of Organic Chemists
Medicinal Chemistry Research
Letter to the Community of Organic Chemists; Medicinal Chemistry Research Progress; Colombo, G. P. and Ricci, S., Ed.; Nova Science Publishers, 2009, pp 1-5. ISBN 978-1-60456-580-5
Structure Determination of Organic Compounds
Springer eBooks, 2000
The use of general descriptive names, registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use.
Journal of Chromatography A, 1216 (2009) 4295–4302
The proanthocyanidin extract from tea (Camellia sinensis) leaves was purified for the further study of the biological role of proanthocyanidins in blister blight leaf disease of tea, which is caused by the fungus Exobasidium vexans. An aqueous acetone extract of proanthocyanidins prepared from healthy tea leaves was partially purified using Sephadex LH-20 chromatography. The crude proanthocyanidin extract obtained was fractionated with high-speed counter-current chromatography (HSCCC) using the solvent system n-hexane-EtOAc-MeOH-water (1:5:1:5). The purity of the each isolated fraction after a single HSCCC run was evaluated by high-performance liquid chromatography (HPLC). Seven fractions of high purity were isolated. The identity of the compound present in each fraction isolated was established using electrospray ionization mass spectrometry (ESI-MS) and nuclear magnetic resonance (NMR) spectroscopy. Five proanthocyanidins and two flavanol digallates, (−)-epigallocatechin digallate (EGCDG) and (−)-epicatechin digallate (ECDG) were isolated. Comparison of spectral data of the proanthocyanidins isolated with those previously reported indicated that all five were known B-type proanthocyanidins with 2,3-cis stereochemistry in both the upper (u-unit) and the terminal (t-unit) units, and 4R configuration of the C-ring in the u-unit. The proanthocyanidins were established to be dimers composed of (−)-epigallocatechin gallate (EGCG), (−)-epicatechin gallate (ECG) and (−)-epiafzelechin gallate (EAG) units with the following structures: EGCG-(4 → 6)-EGCG, ECG-(4 → 6)-EGCG, EGCG-(4 → 6)-ECG, EAG-(4 → 6)-EGCG, ECG-(4 → 6)-ECG by analysis of spectral data. Therefore HSCCC offers a powerful method for the separation of a group of closely related naturally occurring compounds.
Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products, 2010
(Germany), where he received the venia legendi for organic chemistry. In 1970, he became professor ordinarius at the Institute of Organic Chemistry of the University at Köln (Germany). He was dean of the Faculty of Sciences several times and since 1998, he has been emeritus. The fields of research of Herbert Budzikiewicz are mass spectrometry and natural products chemistry, in which he specialized in bacterial metabolites. He is the author of over 500 research publications and he authored and co-authored several books on mass spectrometry. In 2008, he received the Honor Medal of the German Mass Spectrometry Society.