Assessment of the In Vivo Antiproliferative Activity of a Novel Platinum Particulate Pharmacophore (original) (raw)

Platinum and Other Heavy Metal Compounds in Cancer Chemotherapy, 2009

Michele Laus

Raffaella Ravizza

Abstract

Abstract The development of synthetic polymer drug-delivery systems is a promising strategy to improve the therapeutic index of effective but highly toxic anti-cancer agents, such as cisplatin, by taking advantage of the peculiar characteristics of tumor blood and lymphatic ...

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