Optic Nerve Head Parameters in a Turkish Population Over Forty Years of Age (original) (raw)
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Assesment of Optic Nerve Sheath Diameter in Healthy Adults in Turkey
Southern Medical Journal, 2021
Introduction: In this study, we aimed to investigate how the normal values of optic nerve sheath diameter are distributed in normal healthy volunteers in Turkish population. Materials and Methods: This prospective study was planned between November 15, 2019 and April 15, 2020. The study included 160 healthy volunteers who were over 18 years of age and didn’t have acute and chronic systemic disorders. The optic nerve sheath diameters (ONSD) of the subjects were measured from both eyes ultrasonographically. Results: ONSD means (median, IQR) of right and left eyes of the subjects were measured as 4.87 (0.41) mm and 4.86 (0.32) mm, respectively. Right and left eye ONSD measurements were detected lower in female gender than men, and this difference was statistically significant. (p = 0.017 and p = 0.031, respectively). Conclusion: Determination of ONSD optimal reference values in healthy individuals would benefit in predicting increase in intracranial pressure in clinical practice.
2014
Early detection of glaucoma relies on a detailed knowledge of how the normal optic nerve (ONH) varies within the population. The purpose of this study focused on two main areas; 1. To explore the optic nerve head appearance in the normal optometric population and compare the south Asian (principally Pakistani) with the European white population, correcting for possible ocular and non-ocular influences in a multiple regression model. The main findings were: • The optic discs of the South Asian (SA) and White European (WE) populations were not statistically different in size. The SA group possessed discs with increased cupping and thinner neuro-retinal rims (NRR) compared with the WE group. The SA group also demonstrated a more vertically oval shape than the WE population. These differences were significant at the p<0.01 level. • The upper limits of inter-eye asymmetry were: ≤0.2 for cup to disc area ratio, and 3mmHg for intra-ocular pressure (IOP) for both ethnic groups and this d...
Acta Ophthalmologica Scandinavica, 2000
Purpose: To investigate the influence of age, gender, refractive error, and optic disc size on optic disc configuration in Japanese normal eyes. Methods: Ninety-two eyes from 92 visually normal Japanese subjects (mean refractive error∫SD: ª1.26∫2.25 D, range ª8 D to π3 D) were examined using a confocal scanning laser tomograph, TopSS A . The following disc parameters were investigated: disc size, total or quadrant C/D area ratio and neuroretinal rim area, half-depth area, volume below, and average cup depth. Results: The disc diameter ( mean∫SD: 1.84∫0.16 mm) and disc size showed highly significant correlations with the C/D ratio (p∞0.001) and the neuroretinal rim area (p∞0.001). No other correlation was observed. Conclusion: These results indicate that the optic disc diameter and disc size have higher correlations with the optic disc configuration than age, gender, and refractive error in Japanese. These results are similar to those data reported for eyes of Caucasians or Afro Americans, and should be considered when optic discs are evaluated.
Determinants of the Optic Cup to Disc Ratio in an Asian Population
Archives of Ophthalmology, 2008
Objective: To describe the distribution and determinants of the optic cup to disc ratio (CDR) in Malay adults in Singapore. Methods: This population-based, age-stratified study examined 3280 Malay people aged 40 to 80 years in Singapore. Participants underwent a standardized interview and an ocular examination. A slitlamp examination measured the vertical dimensions of the disc and cup, excluding areas of peripapillary atrophy and the Elschnig scleral ring. Results: Vertical CDR was recorded for 3228 right eyes and 3237 left eyes. The mean (SD) CDR was 0.40 (0.15) in both eyes. The CDR in the right eye increased with age (PϽ .001) and was greater in men vs women (age-adjusted CDR, 0.42 vs 0.39; PϽ .001). In multiple linear regression, significant determinants of greater CDR were increasing age, male sex, higher intraocular pressure (IOP), lower diastolic blood pressure, lower body mass index, and previous cataract surgery. Of these, higher IOP was the most important determinant of the CDR. After excluding 149 persons with glaucoma, male sex, higher IOP, lower diastolic blood pressure, lower body mass index, and diabetes mellitus were significant predictors of greater CDR. Conclusion: Greater vertical CDR was related to male sex, higher IOP, lower diastolic blood pressure, and lower body mass index.
Srpski arhiv za celokupno lekarstvo, 2017
Introduction/Objective. Evaluation of the optic nerve head (ONH) is an inevitable procedure in the diagnosis of glaucoma. One of the most common imaging techniques for a quantitative assessment of the topography of the ONH is the Heidelberg retinal tomography II (HRT II). The aim of this study was to determine quantitative stereometric parameters of the ONH by using the HRT II and to investigate any damage of neuroretinal rim in children with suspected glaucoma and compared these data with the group of adults with suspected glaucoma. Methods. This comparative study included 167 (167 eyes) children aged 11?3 years with suspected juvenile glaucoma and 175 adult participants (175 eyes), aged 60?3 years, also with suspected glaucoma, examined between January 2013 and April 2014. Optic nerve head topography and retinal nerve fiber layer thickness measurements were assessed using a HRT II. Results. Data analysis in this study showed that the average mean values for children/adults were: d...
Normative Data of Optic Nerve Head in Nepalese Population by Confocal Scanning Laser Ophthalmoscopy
Purpose: The present study had an aim to ascertain normative data of Optic Nerve Head parameters by using Confocal Scanning Laser Ophthalmoscopy. These normal data can be used as baseline reading for future references; can be used for comparison with special cases like with those having high myopia, glaucoma and other pathologies. Keywords: Optic Nerve Head; Confocal Scanning Laser Ophthalmoscopy; HRT; Glaucoma Methods: The present study design was a cross-sectional descriptive study. Normal subjects who attended the eye clinic of B.P. Koi- rala Lions Center for Ophthalmic Studies, Institute of Medicine, Tribhuvan University Teaching Hospital, Kathmandu were recruited in the present study. All subjects completed an ophthalmological examination that included refraction, best corrected visual acuity, slit-lamp biomicroscopy, fundoscopy, and standard white on white automated perimetry (Humphrey 24-2). Participants were then imaged with HRT II, with the scanner’s focus being adjusted according to the patient’s refraction and to obtain the best image. Results: Fifty normal participants (100 eyes) were included in the study. There were 28 female (56%) and 22 males (44%). The mean ± SD values of age, refractive error (SE) and IOP were 21.38 ± 3.849 years, -0.05 ± 0.174 D and 16.64 ± 2.285 mmHg respec- tively. Average CDR was 0.187 ± 0.010; mean disc area was 2.777 ± 0.641 mm2; mean cup area was 0.55 ± 0.356 mm2; mean cup depth was 0.205 ± 0.798 mm; mean RNFL thickness was 0.292 ± 0.061 mm. Conclusion: All pathologies are due to deviation of normal anatomy and physiology. Hence, establishing normative data of optic nerve head worth a lot in glaucoma diagnosis and other optic nerve head pathology screening. HRT can detect optic disc
Anatomy and evaluation of the optic nerve head
Arquivos Brasileiros de Oftalmologia, 2021
Evaluation of the optic disc is important for the correct diagnosis and follow-up of optic neuropathies, especially glaucoma. The characteristics of the optic disc depend on various factors, including demographic and population aspects, and analysis of these characteristics may vary according to the methods used. The size and format of the neural rim along with the nerve fiber layer are important to the clinician's judgment regarding the susceptibility of the subject to develop glaucoma. In this study, we reviewed the literature to summarize the main methods and its characteristics in the evaluation of the optic nerve head.