Cholesterol side chain triazole analogue via cycloaddition “click”chemistry (original) (raw)

Cholesterol side chain triazole analogue via cycloaddition “click”chemistry

Synthesis

Abstract

Starting from commercially available stigmasterol,an efficient preparation of a cholesterol analogue with a triazole ring was achieved, based on a [3 + 2]-cycloaddition of a cholesterol side chain terminal azide with a terminal acetylene.

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