Frequency of Different Types of Focal Hepatic Lesions on Triphasic Computed Tomography Scan in Adult Patients (original) (raw)

Triphasic computed tomography (CT) scan in focal tumoral liver lesions

JPMA. The Journal of the Pakistan Medical Association, 2011

To assess the diagnostic accuracy of triphasic spiral CT in differentiating benign from malignant focal tumoral liver lesions. The study was conducted in Department of Radiology of Aga Khan University Hospital and Sind Institute of Urology and Transplantation, Karachi from Feb 2006 to Feb 2007. By convenient sampling, 45 patients found to have focal tumoral liver lesions were recruited for one year period and their triphasic CT scans findings were evaluated and later correlated with histopathology. Sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy of triphasic CT scan were calculated. Among 45 patients, 136 liver lesions (11 benign and 125 malignant) were detected with the help of different enhancement patterns. Out of these, 37(82.2%) patients had malignant while 8 (17.8%) had benign lesions. On later histopathological examination, 35 (77.8%) of the total 45 cases had malignant lesions while 10 (22.2%) were diagnosed as benign le...

Study of Liver Lesions using Computed Tomography

This study aimed to study the role of computed tomography (CT) in the diagnosis of liver lesions, to determine which lesion of the liver with high incidence, and to find out the Geographic distribution of the liver lesions in Sudan. This is a retrospective study was conducted at Fedail hospital, and Royal scan Center, Khartoum, Sudan included Sixty patients with focal liver lesions. The results of the study revealed that the high incidence of liver lesions was (45%) among the age group between (41-60) years old. The high incidence of liver lesions was metastasis (33.3%) and solid mass (33.3%) affected age group (41-60) years old (45%), it commonest in male (60%), most patients from center, north, and west of Sudan. The solid mass of the liver was commonest in age group (61-80) years old had an incidence of (45%), it commonest in male (65 and the most affected was right lobe of the liver (50%). This study concluded that triphasic CT scan is a good non-invasive tool and can be used as the first line for differentiating of focal liver lesions. Benign lesions like haemangioma can be reliably differentiated from malignant liver lesion; therefore unnecessary biopsies can be avoided.

MRI characterization of 124 CT-indeterminate focal hepatic lesions: evaluation of clinical utility

HPB, 2007

Objective. To evaluate the diagnostic yield of MRI performed for characterization of focal hepatic lesions that are interpreted as indeterminate on CT. Patients and methods. In a retrospective investigation, 124 indeterminate focal hepatic lesions in 96 patients were identified on CT examinations over 5 years from 1997 to 2001. All patients had MRI performed for the liver within 6 weeks of their CT examination. CT and MR images were reviewed independently by two separate groups of two radiologists. The value of MRI in characterizing these lesions was assessed. Diagnoses were confirmed based on histology, characteristic imaging features, and clinical follow-up. Results. MRI definitely characterized 73 lesions (58%) that were indeterminate on CT. MRI was accurate in 72/73 of these lesions. MRI could not definitely characterize 51 lesions (42%). Ten lesions were not visualized on MRI, and follow-up imaging confirmed that no lesion was present in eight of these cases (pseudolesions). Conclusion. MRI is valuable for the characterization of indeterminate focal hepatic lesions detected on CT.

Non-invasive diagnosis of focal liver lesions: an individualized approach

Cancer Imaging, 2012

Modern cross-sectional imaging with multidetector computed tomography (MDCT) or magnetic resonance imaging (MRI) often reveals small focal liver lesions, which puts pressure on the reporting radiologist to characterize these tiny lesions. On the other hand, in patients with underlying diffuse liver disease, such as cirrhosis or severe steatosis, the detection of focal liver lesions can be quite difficult. Strategies for optimal detection and characterization of focal liver lesions should be developed according to the clinical situation, the likelihood of malignant disease and the presence of underlying diffuse liver disease. The presence or absence of a clinical history of cancer determines the algorithm for further characterization: work-up with contrast-enhanced MRI, biopsy or follow-up. In patients with chronic liver disease, recent guidelines on the detection of hepatocellular carcinoma (HCC) favour the use of multiphasic MRI or MDCT, which allows confident diagnoses of HCC 41 cm. For lesions 51 cm in chronic liver disease, follow-up is recommended. In patients with moderate to severe steatosis, contrast-enhanced MDCT has low diagnostic yield for the detection of liver lesions; contrast-enhanced MRI is far superior. This review describes successful strategies for the detection and characterization of focal liver lesions in different clinical scenarios.

Percutaneous CT-guided Biopsy of Focal Liver Lesions – Long- term Experience with more than 300 Procedures

Journal of Gastrointestinal and Liver Diseases

Background and Aims: Despite the undeniable ongoing development of cross-sectional imaging methods, not all focal liver lesions (FLLs) have a typical pattern. An image-guided biopsy using a percutaneous approach might safely provide a final histological diagnosis of the FLLs. We aimed to evaluate the accuracy, efficiency, complication rate, technical features, and relationships between the followed parameters of computed tomography (CT)-guided percutaneous biopsies of FLLs using a retrospective approach. Methods: 303 percutaneous biopsy procedures in 295 patients were carried out in patients with suspected or indeterminate FLLs over a 10-year period. The median size of the tumors was 44 mm (15 - 144 mm). Median age of patients was 67 years (25 to 87 years). Skin-to-lesion distance was variable, from 30 mm to 138 mm (median length 59 mm). In 200 procedures (66%) malignant disease was known from the patients´ clinical history. Results: In 288 biopsies (95%) the results were true posit...

Current methods of focal liver lesion diagnosis

Polish Annals of Medicine, 2013

Keywords: MDCT MRI DW-MRI Liver Focal Lesion a b s t r a c t Introduction: The widespread availability of non-invasive radiological and diagnostic imaging techniques significantly contributed to the detectability of focal lesions in the liver. Ultrasonography, computed tomography (CT) multidetector CT (MDCT), conventional magnetic resonance imaging (MRI), diffusion-weighted magnetic resonance imaging (DW-MRI) and isotope imaging are used for focal liver diagnosis.

Evaluation of Focal Hepatic Lesion and associated changes in Gallbladder and Kidneys using Spiral Computed Tomography

Pakistan Journal of Health Sciences

Focal hepatic lesions are the lesions in the liver apart from its usual parenchyma. Objective: To check the efficiency of triphasic computed tomography for diagnosing benign and malignant focal liver lesions and to assess frequencies of both types of liver lesions. Methods: On 60 patients, triphasic CT scan for the liver was performed in Allied Hospital, Faisalabad. The liver was scanned in the arterial, the portal-venous, and the delayed phases followed by contrast injection. During all of these phases evaluation of lesions was made on enhancement patterns and frequencies of each lesion was checked. Results: The results showed that out of 60 patients 26(43.3%) were diagnosed with benign and 34(56.67%) were diagnosed with malignant focal liver lesions. Benign cases had a higher frequency of Haemangioma and malignant cases had a higher frequency of hepatocellular carcinoma. The overall study showed the percentage of incidents in gallbladder and renal system. Conclusions: The triphasi...

Italian guidelines for noninvasive imaging assessment of focal liver lesions

2011

on behalf of the Multidisciplinary Guidelines Development Group Objectives To develop guidelines for the noninvasive imaging assessment of focal liver lesions comparing different imaging modalities focused on (i) evaluating the imaging techniques in terms of (a) diagnostic accuracy; (b) role in the management of oncologic patients; (c) follow-up of benign lesions; and (ii) developing standard procedure for their use in patients with focal liver lesions that require targeted diagnostic characterization. Methods An explicit search strategy was used to conduct a systematic review of the literature in the English language from January 2000 to October 2007; the search covered PubMed, Embase, Pascal, SciSearch, and Cochrane Library databases. A panel of experts evaluated the selected studies and conveyed their view. Results The online search yielded 4960 titles and abstracts from which 176 studies were considered suitable for the final adherence-to-guidelines topic evaluation. An evidence...