Infiltration Anaesthesia for Tympanoplasty: A Comparison of Dexmedetomidine and Clonidine as Adjuvants to Lignocaine and Adrenaline (original) (raw)

International Journal of Advanced Research

Abstract

Background: For many decennia, local anaesthetics have been utilised for wound infiltration analgesia. α -2 Adrenoceptors as adjuvants have an advantageous effect in prolonging the time of peripheral nerve blocks is a locally mediated action and not replicated by given systemically. An increasing impact on lignocaine-induced suppression of the C-fibre action potential is thought to be the cause of its synergistic activity with lignocaine in extending the duration. we evaluated Dexmedetomidine and clonidine when administered with lignocaine during infiltration anaesthesia for tympanoplasty. Methodology: 50 patients of 18-60 years who were enrolled for tympanoplasty under local anaesthesia were arbitrarily split into two equal groups. 12 ml of 2% lignocaine with adrenaline + clonidine + 1 ug/kg were injected into Group C (n = 25), and 12 ml of 2% lignocaine with adrenaline + dexmedetomidine + 1 ug/kg were injected into Group D (n = 25). Hemodynamic parameters, sedation score, analges...

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