Morphological pattern of salivary gland tumours (original) (raw)
Related papers
2016
Background: Salivary gland tumors (SGTs) are the most histologically heterogeneous group of tumors with greatest diversity of morphologic features among their cells and tissues. The present study was aimed at to analyze the relative frequency of individual SGTs and to correlate the various SGTs according to age, sex, anatomical site, and duration of the lesion by retrieving them from the registry of Department of Oral Pathology and Microbiology, Government Dental College and Hospital Nagpur, from 1977 to July 2008 (31 years). Materials and Methods: 82 cases of SGTs were retrieved from the registry of Department of Oral Pathology and Microbiology, Government Dental College and Hospital, Nagpur. Results: The overall annual frequency of all SGTs was found to be 2.64 cases per year. Minor salivary glands (74.4%) were found to be more commonly involved as compared to major salivary gland (25.6%). Conclusion: Benign tumors were found in a relatively younger age group than the malignant tu...
Clinicopathological Analysis of Salivary Gland Tumours: An Observational Study
2019
Background: Salivary gland tumour is a comparatively sporadic and morphologically varied collection of pathologic entities. Hence; we histopathologically analyzed the salivary gland tumour in the present study.Materials & methods: The present analysis included histopathologic assessment of salivary gland neoplasms. All the biopsies received in the department were recorded. H and E stained slides were made and were assessed by experienced and certified oral pathologists. Histopathologic diagnosis were recorded in Microsoft excel sheet and were analyzed by SPSS software. Results: Biopsies of a total of 70 salivary gland neoplasms were studies in the present study. Among these, 40 were benign while the remaining 30 were malignant in nature. Total frequency of occurrence of Pleomorphic adenoma, Basal cell adenoma and Warthin’s tumour was 25.6%, 10% and 14.2% respectively. Frequency of occurrence of Adenoid cystic adenoma, mucoepidermoid carcinoma, acinic cell carcinoma, polymorphous low...
International Journal of Otorhinolaryngology and Head and Neck Surgery, 2020
Background: Salivary gland tumours constitute 3-4% of all head and neck cancers (mostly benign). These tumours are epithelial (95%) or mesenchymal in origin. Pleomorphic adenoma is the most common benign salivary gland tumour and mucoepidermoid carcinoma (45%) is the most common malignant salivary gland tumour followed by adenoid cystic carcinoma (30%). The parotid, submandibular and the minor salivary glands of palate are commonly involved and the sublingual gland is rarely affected.Methods: Hospital based cross sectional study was done in a tertiary care centre during a period of 1 year, which included 21 patients (10 men and 11 women). Patients were analysed according to age, gender, food habits, histopathological type and site of the tumour and treatment strategy.Results: All the cases were from upper Assam province sharing a particular demographic pattern between 19-65 years. Peak incidence in males was fourth decade and females was third decade. Male female ratio was 0.9:1. Ou...
HISTOPATHOLOGICAL SPECTRUM OF SALIVARY GLAND TUMOURS: A HOSPITAL BASED STUDY
Background: Salivary gland tumors are common neoplasms of head and neck region. These tumors are complex andsome of them exhibit great deal of morphologic overlap .The majority of these neoplasms are benign. These tumours can occur in both major and minor salivary glands. 80% of major salivary gland tumoursoccur in the parotid glands, while most minor salivary tumours are located in the palate. As a general rule in clinical practice, the smaller the salivary gland is, the more likely the tumouris malignant. Objective: This study was carried out to study the histopathological spectrum of salivary gland tumors and to know their pattern of distribution. Material and Methods:-This is a two year retrospective study which was conducted in the Post graduate department of pathology Government Medical College Srinagar from January 2015 to December 2016 . Post surgical specimens were studied in detail to know the histological patterns. In each patient, age, sex, site and histopathological diagnosis was seen from record section of the department. The histological diagnosis of each individual tumor was based on the 2005 WHO classification of salivary gland tumors. Results:- During two year ( from January 2015 to December 2016), 100 cases of salivary gland tumors were diagnosed with peak incidence in third to fourth decade (48%).Among these, 63(63%) cases were benign and 31(31%) cases were malignant. The commonest site was parotid gland (68%) followed by submandibular glands(19%) and minor salivary gland tumors were 13%. Among benign tumours of salivary glands pleomorphic adenoma (42%) was most common followed by Warthintumour (12%),basal cell adenoma (7%) andMyoepithelioma (2%) and among malignant tumours,Mucoepidermoid carcinoma (46%) was most common followed by Adenoid cystic carcinoma (32.5%), Carcinoma ex pleomorphic adenoma (10.8%), Acinic cell carcinoma and Polymorphous low grade adenocarcinoma each comprising of (5.4%). Conclusion: Histopathological study of salivary gland lesions is the most important method in establishing the final diagnosis and accordingly guides in the specific management.
Tropical Journal of Pathology and Microbiology, 2018
Background: Salivary gland tumors (SGTs) are rare neoplasm of head and neck region. The salivary gland tumours vary widely in histopathological appearance. Also, epidemiological data of these tumors in various parts of the world are different. And so the study of SGTs for their biology and clinical characteristics can be helpful for a better understanding. Objectives: The objective of this study was to study types and new entities, common site of distribution and histomorphological spectrum of salivary gland tumors (SGTs). Materials and Methods: It was a retrospective followed by prospective study. Pertinent clinical history like age, duration of the lesion, site of the lesion, significant family and personal history, history of associated diseases was recorded. Specimens consisted of incisional biopsies were examined microscopically by the expert pathologist. Details of specimens noted in Performa include dimensions, appearance of external and cut surface and presence of lymph nodes, their size and number. Observations: Total 70 cases of SGTs could be included in the study. Among them 56 (80%) were benign and 14 (20%) were malignant. Parotid is commonest salivary gland involved with 75.71% of all tumors, followed by submandibular with 21.42% and minor salivary glands with 1(1.4%) of salivary gland tumors. among benign tumors Pleomorphic adenoma is most common with 70% of all benign SGTs followed by Warthin tumors (7%). Among malignant tumors commonest is Mucoepidermoid carcinoma with 14.28% of all SGTs. Female preponderance was clearly found in malignan at SGTs. Conclusion: Parotid is most common site for the SGT. And pleomorphic adenoma and the Warthin tumors are the common benign tumors involve parotid gland the most. Among malignant tumors mucoepidermoid carcinoma are the commonest with female preponderance. While other carcinoma like adenoid cystic carcinoma and SCC are also common.
Descriptive Epidemiology of Salivary Gland Tumors in General Hospitals of Lahore, Pakistan
Pak-Euro Journal of Medical and Life Sciences
Background: Salivary gland tumours are relatively rare when compared with other oral neoplasms and morphologically diverse group of lesions. This study aimed to determine the demographic findings and distribution of salivary gland neoplasms. A relatively large group of patients was in Lahore from all over the country especially Punjab.Materials and mathods. A reterospective cross sectional study was performed to diagnose the prevalence of these tumors both benign and malignant in Pakistani population. primary epithelial SGT 76 cases are included in 5 years from 2013-2017. The data was collected from previously designed questionaires.Results:The general features of the relevant salivary gland tumors were analysed in the first section. Out of 74 cases, 47 were males and 29 were females. The mean age at the time of diagnosis was about 41 years. Overall these tumors were seen more frequently in males than in females.The more common site is Parotid glands. The most frequent tumor is pl...
Clinicopathological Study of Salivary Gland Tumours in a Tertiary Care Hospital in Central India
GLOBAL JOURNAL FOR RESEARCH ANALYSIS, 2022
X 113 GJRA-GLOBAL JOURNAL FOR RESEARCH ANALYSIS Salivary gland tumours are a relatively rare and morphologically diverse group of lesions, thus are highly prone to diagnostic confusion. Worldwide reports show difference in incidence, prevalence and histological type of this tumours. Location, age and gender distribution of salivary gland tumours vary depending on race and geographical conditions. OBJECTIVE 1) To study the clinicopathological ndings in Salivary Gland Tumours 2) To study various surgical modalities of treatment undertaken for salivary gland tumours RESULTS: Pleomorphic Adenoma (77.27%) was the most common benign tumour followed by warthins tumour (9.09%). Mucoepidermoid carcinoma was the most common malignant tumour in parotid gland. In our study Ultrasonography was found to had Sensitivity of 52.63% and Specicity of 95.45% And Fine needle aspiration cytology had sensitivity of 78.95% and specicity of 90.90% FNAC continues to be a reliable diagnostic technique in hands of an experienced CONCLUSION: cytopathologist. Ultrasonography is a reliable radiological rst line investigations for salivary gland tumours.
A Clinicopathological Analysis of 75 Salivary Gland Tumors at Mayo Hospital, Lahore
Pakistan Journal of Medical and Health Sciences, 2022
Aim: To describe the clinic-o-pathological pattern of patients presented with salivary gland tumors at Department of Maxillofacial surgery Mayo hospital Lahore during time period of one year from 1st January 2019 to 31st December 2019. Methods: This was a retrospective cross-sectional study conducted at Department of Oral and Maxillofacial Surgery, Mayo Hospital Lahore. 75 cases of Salivary gland tumors in the head and neck region were identified. Patient’s medical record and pathology reports were retrieved and carefully reviewed by a senior doctor to collect basic demographic data as well as tumor related information. Data entry and analysis was done with the help of SPSS version-26. Chi Square Test/Fisher exact test was applied to see the association between qualitative variables. Results: In this study Mean age of patients in this study was 40.45±13.18. Male patients were predominant as compared to female patients; Male 53.3% & Female 46.7%.The most frequent tumor among patients...
Retrospective study of 124 cases of salivary gland tumors and literature review
Journal of Clinical and Experimental Dentistry
Background: Salivary gland tumors are a rare and morphologically diverse group of lesions and their frequency is still unknown in several parts of the world. The knowledge of its population characteristics contributes to a better understanding of its etiopathogenesis. Objectives: This study investigated the frequency of salivary gland tumors in a region of southern Brazil and compared these data in a literature review. Material and Methods: A retrospective study was conducted of salivary gland tumors diagnosed at two pathology centers from 1995 to 2016. Patient age and gender, tumor site and frequency, histopathological diagnosis, and symptomatology were evaluated. Chi-squared tests were used to assess the associations between variables. To compare our data, we also conducted a literature review of publications in the PubMed and LILACS databases of retrospective studies of salivary gland tumors. Results: A total of 124 salivary gland tumor cases was identified, 81 (65.3%) of which were classified as benign and 43 (34.6%) as malignant. Most tumors occurred in the parotid gland (57.2%). Pleomorphic adenoma was the most common tumor (59.6%), followed by adenocarcinoma not otherwise specified (8.8%). The tumors occurred more often in women (54.8%) than in men (45.2%). Malignant tumors were associated with pain in 31.4% of cases (p <0.05). The literature review included 35 articles from different countries. Women were most affected, with a mean age of 41.7 years. The most common benign tumor was pleomorphic adenoma (48.2%) and the most common malignant tumor was mucoepidermoid carcinoma (8.7%). Conclusions: The results of the present study showed that salivary gland tumors are rare. The parotid gland is the most common location and pleomorphic adenoma are the most frequent lesions. The malignant tumors presented as several histological types and the incidence was variable globally.