Elimination of the O-linked glycosylation site at Thr 104 results in the generation of a soluble human-transferrin receptor (original) (raw)

Nonacylated human transferrin receptors are rapidly internalized and mediate iron uptake

Shuqian Jing

The Journal of biological chemistry, 1990

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Elimination of the 0Linked Glycosylation Site at Thr 104 Results in the Generation of a Soluble Human-Transferrin Receptor

Caroline Enns

1994

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Two genetic loci participate in the regulation by iron of the gene for the human transferrin receptor

Joe Harford

Proceedings of the …, 1988

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Structure-Based Mutagenesis Reveals Critical Residues in the Transferrin Receptor Participating in the Mechanism of pH-Induced Release of Iron from Human Serum Transferrin

Anne Mason

Biochemistry, 2012

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A mutated transferrin receptor lacking asparagine-linked glycosylation sites shows reduced functionality and an association with binding immunoglobulin protein

Caroline Enns

Journal of Biological Chemistry, 1991

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N-Linked Glycosylation Is Required for Transferrin-Induced Stabilization of Transferrin Receptor 2, but Not for Transferrin Binding or Trafficking to the Cell Surface

Caroline Enns

Biochemistry, 2013

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The Molecular Mechanism for Receptor-Stimulated Iron Release from the Plasma Iron Transport Protein Transferrin

Caroline Enns

Structure, 2005

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Ionic residues of human serum transferrin affect binding to the transferrin receptor and iron release

Sam Dundon, Ph.D.

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Receptor recognition sites reside in both lobes of human serum transferrin

John Brandts, Anne Mason

The Biochemical journal, 1997

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A new role for the transferrin receptor in the release of iron from transferrin

Philip Aisen

Biochemistry, 1991

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The Promoter Region of the Human Transferrin Receptor Gene

Joe Harford

Annals of the New York Academy of Sciences, 1988

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The complete amino acid sequence of human serum transferrin

Keith Brew

Proceedings of the National Academy of Sciences, 1982

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Crystal Structure of the Ectodomain of Human Transferrin Receptor

Melissa Parisi

Science, 1999

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Transferrin receptor 2 mediates uptake of transferrin-bound and non-transferrin-bound iron

John Olynyk

Journal of Hepatology, 2008

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Receptor-modulated iron release from transferrin: differential effects on N- and C-terminal sites

Philip Aisen

Biochemistry, 1991

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The Synergistic Anion-Binding Sites of Human Transferrin: Chemical and Physiological Effects of Site-Directed Mutagenesis †

Philip Aisen

Biochemistry, 2002

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The low pKa value of iron-binding ligand Tyr188 and its implication in iron release and anion binding of human transferrin

Anne Mason

FEBS Letters, 2004

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Transcriptional regulation by iron of the gene for the transferrin receptor

Joe Harford

Molecular and cellular biology, 1986

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The Mechanism of Iron Release from the Transferrin-Receptor 1 Adduct

Nguyêt-thanh Ha-duong

Journal of Molecular Biology, 2006

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Transferrin receptors in the human gastrointestinal tract

Diponkar Banerjee

Gastroenterology, 1986

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Acquisition of the functional properties of the transferrin receptor during its biosynthesis

Caroline Enns

Journal of Biological Chemistry, 1991

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Molecular and Cellular Characterization of Transferrin Receptor 2

Nathan Subramaniam

Cell Biochemistry and Biophysics, 2002

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Minireview: Genetic and pathophysiological aspects of serum transferrin

Arjumand S. Warsy

Biochemical Education, 1996

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Recombinant human transferrin: Beyond iron binding and transport

Shengwu Ma

Biotechnology Advances, 2011

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The C2 variant of human serum transferrin retains the iron binding properties of the native protein

Chiara Gabbiani

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2005

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The role of transferrin receptor 1 and 2 in transferrin-bound iron uptake in human hepatoma cells

Ketil Thorstensen

AJP: Cell Physiology, 2009

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The Crystal Structure of Iron-free Human Serum Transferrin Provides Insight into Inter-lobe Communication and Receptor Binding

Stephen Everse, Anne Mason

Journal of Biological Chemistry, 2006

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Iron uptake from plasma transferrin by a transferrin receptor 2 mutant mouse model of haemochromatosis

John Olynyk

Journal of Hepatology, 2010

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The role of transferrin in the mechanism of cellular iron uptake

Ketil Thorstensen

Biochemical Journal, 1990

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Structural, functional, and tissue distribution analysis of human transferrin receptor-2 by murine monoclonal antibodies and a polyclonal antiserum

Silvia Deaglio

…, 2002

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