Nrf Transcription Factors in Keratinocytes Are Essential for Skin Tumor Prevention but Not for Wound Healing
Daniel Hohl
Molecular and Cellular Biology, 2006
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Attenuation of UVB-Induced Sunburn Reaction and Oxidative DNA Damage with no Alterations in UVB-Induced Skin Carcinogenesis in Nrf2 Gene-Deficient Mice
Yasuhiro Fujisawa
Journal of Investigative Dermatology, 2008
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Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice
Minerva Ramos-gómez
Proceedings of the National Academy of Sciences, 2001
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Loss of Nrf2 abrogates the protective effect of Keap1 downregulation in a preclinical model of cutaneous squamous cell carcinoma
Albena Dinkova-kostova
Scientific Reports, 2016
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NRF2 and the Ambiguous Consequences of Its Activation during Initiation and the Subsequent Stages of Tumourigenesis
Albena Dinkova-kostova
Cancers, 2020
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Nrf2/Keap1 Pathway and Expression of Oxidative Stress Lesions 8-hydroxy-2'-deoxyguanosine and Nitrotyrosine in Melanoma
Ylermi Soini
Anticancer research, 2016
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Data from Nrf2 Activation Protects against Solar-Simulated Ultraviolet Radiation in Mice and Humans
Albena Dinkova-kostova
2023
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Contradictory roles of Nrf2/Keap1 signaling pathway in cancer prevention/promotion and chemoresistance
narges soozangar
DNA Repair, 2017
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Oxidative Stress and Oxidative Damage in Carcinogenesis
James Klaunig
Toxicologic Pathology, 2009
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Autocrine and Paracrine Regulation of Keratinocyte Proliferation through a Novel Nrf2-IL-36γ Pathway
Matthias Schäfer
Journal of immunology (Baltimore, Md. : 1950), 2016
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Nrf2 activation does not affect adenoma development in a mouse model of colorectal cancer
Albena Dinkova-kostova
Communications biology, 2021
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Metabolic Activation of Carcinogens by Keratinocytes
David Bickers
Annals of the New York Academy of Sciences, 1988
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NRF2 and p53: Januses in cancer?
Barak Rotblat
Oncotarget, 2012
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Activation of the NRF2 antioxidant program generates an imbalance in central carbon metabolism in cancer
Anastasia-Maria Zavitsanou
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Disruption of NAD(P)H:quinone oxidoreductase 1 gene in mice leads to 20S proteasomal degradation of p63 resulting in thinning of epithelium and chemical-induced skin cancer
Anil K Jaiswal
Oncogene, 2011
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The dual role of Nrf2 in melanoma: a systematic review
Nasim Dana
BMC Molecular and Cell Biology
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Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis
Dipti Mangal
Nature, 2011
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Oxidative stress indicated by elevated expression of Nrf2 and 8-OHdG promotes hepatocellular carcinoma progression
Surasit Suwannasin
Medical Oncology, 2017
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Reactive Oxygen and Nitrogen Oxide Species-induced Stress, a Major Intrinsic Factor Involved in Carcinogenic Processes and a Possible Target for Cancer Prevention
Dai Nakae
Asian Pacific journal of cancer prevention: APJCP
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Roles of Keap1–Nrf2 System in Upper Aerodigestive Tract Carcinogenesis
Takafumi Suzuki
Cancer Prevention Research, 2012
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The Role of Nrf2 Activity in Cancer Development and Progression
Diana Cenariu
Cancers
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The transcription factor NRF2 enhances melanoma malignancy by blocking differentiation and inducing COX2 expression
Svenja Meierjohann
Oncogene
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The effects of reactive species on the tumorigenic phenotype of human head and neck squamous cell carcinoma (HNSCC) cells
Susan Mallery
Anticancer research
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Oxidative damage control in a human (mini-) organ: Nrf2 activation protects against oxidative stress-induced hair growth inhibition
Fei-Ling Lim
The Journal of investigative dermatology, 2016
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Nrf2-Keap1 Activation, A Promising Strategy in the Prevention of Cancer
promise Taro
Free Radicals and Antioxidants, 2016
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Reactive oxygen species from NAD (P) H: quinone oxidoreductase constitutively activate NF-κB in malignant melanoma cells
anne sturrock
American Journal of …, 2001
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Epigenetic modifications of triterpenoid ursolic acid in activating Nrf2 and blocking cellular transformation of mouse epidermal cells
Christina Ramirez
The Journal of Nutritional Biochemistry, 2015
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Evaluation of mitochondrial function and metabolic reprogramming during tumor progression in a cell model of skin carcinogenesis
C Vallejo
Biochimie, 2013
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Requirement and Epigenetics Reprogramming of Nrf2 in Suppression of Tumor Promoter TPA-Induced Mouse Skin Cell Transformation by Sulforaphane
Tin Khor
Cancer Prevention Research, 2014
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