original ) (raw )Polymerase μ in non-homologous DNA end joining: importance of the order of arrival at a double-strand break in a purified system
Michael Lieber
Nucleic Acids Research, 2020
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DNA polymerase λ can elongate on DNA substrates mimicking non-homologous end joining and interact with XRCC4–ligase IV complex
Wei Fan
Biochemical and Biophysical Research Communications, 2004
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The DNA polymerase l is required for the repair of non-compatible DNA double strand breaks by NHEJ in mammalian cells
François Boudsocq , Pascale Bertrand
Nucleic Acids Research, 2000
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Bridging of double-stranded breaks by the nonhomologous end-joining ligation complex is modulated by DNA end chemistry
Michael Lieber
Nucleic acids research, 2016
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Non-homologous DNA end joining and alternative pathways to double-strand break repair
Michael Lieber
Nature Reviews Molecular Cell Biology, 2017
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A Gradient of Template Dependence Defines Distinct Biological Roles for Family X Polymerases in Nonhomologous End Joining
Luis Blanco
Molecular Cell, 2005
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The DNA polymerase λ is required for the repair of non-compatible DNA double strand breaks by NHEJ in mammalian cells
Yvan Canitrot
Nucleic acids …, 2006
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The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway
Michael Lieber
Annual Review of Biochemistry, 2010
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“An End to a Means”: How DNA-End Structure Shapes the Double-Strand Break Repair Process
Jose F. Ruiz
Frontiers in Molecular Biosciences, 2020
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Organization and dynamics of the nonhomologous end-joining machinery during DNA double-strand break repair
Michael Lieber
Proceedings of the National Academy of Sciences of the United States of America, 2015
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The DNA polymerase is required for the repair of non-compatible DNA double strand breaks by NHEJ in mammalian cells
Pascale Bertrand
Nucleic Acids Research, 2006
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Molecular Basis for DNA Double-Strand Break Annealing and Primer Extension by an NHEJ DNA Polymerase
Luis Blanco
Cell Reports, 2013
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DNA double strand break repair via non-homologous end-joining
David Chen
Translational cancer research, 2013
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Druggable binding sites in the multicomponent assemblies that characterise DNA double-strand-break repair through non-homologous end joining
Tom Blundell
Essays in Biochemistry, 2020
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Time-lapse crystallography snapshots of a double-strand break repair polymerase in action
Juno Krahn
Nature Communications, 2017
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Polymerase theta-helicase promotes end joining by stripping single-stranded DNA-binding proteins and bridging DNA ends
Jeffrey Schaub
Nucleic Acids Research, 2022
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Efficient Processing of DNA Ends during Yeast Nonhomologous End Joining. EVIDENCE FOR A DNA POLYMERASE beta (POL4)-DEPENDENT PATHWAY
Michael Lieber
Journal of Biological Chemistry, 1999
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Involvement of DNA polymerase in the repair of a specific subset of DNA double-strand breaks in mammalian cells
Bernard Lopez
Nucleic Acids Research, 2007
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Involvement of DNA polymerase μ in the repair of a specific subset of DNA double-strand breaks in mammalian cells
Yvan Canitrot
Nucleic acids …, 2007
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Polymerase is a robust terminal transferase that oscillates between three different mechanisms during end-joining
TATIANA KENT
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DNA polymerase μ is a global player in the repair of non-homologous end-joining substrates
Romain Chayot
DNA Repair, 2012
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Different DNA End Configurations Dictate Which NHEJ Components are Most Important for Joining Efficiency
Michael Lieber
Journal of Biological Chemistry, 2016
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A specific N-terminal extension of the 8 kDa domain is required for DNA end-bridging by human Pol and Pol
Susana Guerra
Nucleic Acids Research, 2013
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Polymerase θ is a robust terminal transferase that oscillates between three different mechanisms during end-joining
TATIANA KENT
eLife, 2016
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Molecular basis of microhomology-mediated end-joining by purified full-length Polθ
TATIANA KENT
Nature Communications
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Atomic structure and nonhomologous end-joining function of the polymerase component of bacterial DNA ligase D
Christopher Lima
Proceedings of The National Academy of Sciences, 2006
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Modulation of RNA polymerase processivity affects double-strand break repair in the presence of a DNA end-binding protein
Alice Wen
2022
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DNA double-strand break repair from head to tail
John Tainer
Current Opinion in Structural Biology, 2002
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Template strand scrunching during DNA gap repair synthesis by human polymerase λ
Lalith Perera
Nature Structural & Molecular Biology, 2009
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Translesion DNA synthesis-assisted non-homologous end-joining of complex double-strand breaks prevents loss of DNA sequences in mammalian cells
Zvi Livneh
Nucleic Acids Research, 2009
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Involvement of Polynucleotide Kinase in a Poly(ADP-ribose) Polymerase-1-dependent DNA Double-strand Breaks Rejoining Pathway
Bernard Salles
Journal of Molecular Biology, 2006
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Achieving selectivity in space and time with DNA double-strand-break response and repair: molecular stages and scaffolds come with strings attached
Tom Blundell
Structural Chemistry, 2016
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Structure and function of the double-strand break repair machinery
John Tainer
DNA Repair, 2004
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