Rapid Fusion of Synaptic Vesicles with Reconstituted Target SNARE Membranes (original) (raw)

In vitro fusion of single synaptic and dense core vesicles reproduces key physiological properties

Nature Communications

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Frontiers in molecular neuroscience, 2017

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Science, 2004

SNARE-Driven, 25-Millisecond Vesicle Fusion In Vitro

Biophysical Journal, 2005

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Roger B Sutton

Nature Structural & Molecular Biology, 2010

The core membrane fusion complex governs the probability of synaptic vesicle fusion but not transmitter release kinetics

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Synaptotagmin arrests the SNARE complex before triggering fast, efficient membrane fusion in response to Ca2+

Nature Structural & Molecular Biology, 2008

Ca2+-Triggered Synaptic Vesicle Fusion Initiated by Release of Inhibition

Qiangjun Zhou

Trends in Cell Biology, 2018

Lipid-Anchored SNAREs Lacking Transmembrane Regions Fully Support Membrane Fusion during Neurotransmitter Release

Zhiping Pang

Neuron, 2013

Evidence That Vesicles Undergo Compound Fusion on the Synaptic Ribbon

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Determinants of liposome fusion mediated by synaptic SNARE proteins

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Proceedings of the National Academy of Sciences, 2004

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Scientific Reports

synaptotagminMutants Reveal Essential Functions for the C2B Domain in Ca2+-Triggered Fusion and Recycling of Synaptic VesiclesIn Vivo

The Journal of Neuroscience, 2001

Reconstituted synaptotagmin I mediates vesicle docking, priming, and fusion

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The Journal of cell biology, 2011

A common origin of synaptic vesicles undergoing evoked and spontaneous fusion

Magalie Martineau

Nature Neuroscience, 2010

Gβγ directly modulates vesicle fusion by competing with synaptotagmin for binding to neuronal SNARE proteins embedded in membranes

Brian Page

Journal of Biological Chemistry, 2017

Rapid structural change in synaptosomal-associated protein 25 (SNAP25) precedes the fusion of single vesicles with the plasma membrane in live chromaffin cells

Wolfhard Almers

Proceedings of the National Academy of Sciences, 2013

Synaptic proteins promote calcium-triggered fast transition from point contact to full fusion

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eLife, 2012

Fusion Pore Dynamics Are Regulated by Synaptotagmin•t-SNARE Interactions

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Single-Molecule Studies of the Neuronal SNARE Fusion Machinery

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Membrane Fusion Induced by Neuronal SNAREs Transits through Hemifusion

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Journal of Biological Chemistry, 2005

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Journal of Cell Biology, 1998

A synaptotagmin suppressor screen indicates SNARE binding controls the timing and Ca2+ cooperativity of vesicle fusion

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eLife

A Novel Synaptic Vesicle Fusion Path in the Rat Cerebral Cortex: The “Saddle” Point Hypothesis

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