Phosphorylated hydroxyethylamines as novel inhibitors of the bacterial cell wall biosynthesis enzymes MurC to MurF (original) (raw)

Bioorganic & Medicinal Chemistry Letters, 2009

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Bioorganic Chemistry, 2014

Identification and Characterization of New Inhibitors of the Escherichia coli MurA Enzyme

Ignatius Turchi

Antimicrobial Agents and Chemotherapy, 2001

INDO AMERICAN JOURNAL OF PHARMACEUTICAL RESEARCH MUR-A: A CRITICAL TARGET BEHIND NEW ANTIBACTERIAL DRUG DISCOVERY

Veena Kasture, poonam patil

Benzene-1,3-dicarboxylic acid 2,5-dimethylpyrrole derivatives as multiple inhibitors of bacterial Mur ligases (MurC–MurF)

Bioorganic & Medicinal Chemistry, 2014

Structure-activity relationships of new cyanothiophene inhibitors of the essential peptidoglycan biosynthesis enzyme MurF

Chris Randall

European journal of medicinal chemistry, 2013

An approach to design, in silico predictions and molecular docking studies of 1,3,4-oxadiazolyl sulphonamides as possible inhibitors of bacterial Mur enzymes, the amino acid ligases in peptidoglycan synthesis

haseena banu

Journal of Advanced Research in Biotechnology, 2017

Discovery of novel benzene 1,3-dicarboxylic acid inhibitors of bacterial MurD and MurE ligases by structure-based virtual screening approach

Tom Solmajer

Bioorganic & Medicinal Chemistry Letters, 2009

Inhibitors of the bacterial cell wall biosynthesis enzyme Mur D

Stewart Fisher

Bioorganic & Medicinal Chemistry Letters, 1998

A peptide inhibitor of MurA UDP- N-acetylglucosamine enolpyruvyl transferase: The first committed step in peptidoglycan biosynthesis

Roger C . Levesque

Peptides, 2006

Utility of Muropeptide Ligase for Identification of Inhibitors of the Cell Wall Biosynthesis Enzyme MurF

Karen Bush

Antimicrobial Agents and Chemotherapy, 2005

Discovery of new inhibitors of the bacterial peptidoglycan biosynthesis enzymes MurD and MurF by structure-based virtual screening

Ian Chopra

Bioorganic & Medicinal Chemistry, 2009

Design, Synthesis and in vitro Biochemical Activity of Novel Amino Acid Sulfonohydrazide Inhibitors of MurC

Rok Frlan

Acta chimica Slovenica, 2011

New 5-benzylidenethiazolidin-4-one inhibitors of bacterial MurD ligase: Design, synthesis, crystal structures, and biological evaluation

European Journal of Medicinal Chemistry, 2011

Structure-Based Design of a New Series of d -Glutamic Acid Based Inhibitors of Bacterial UDP- N -acetylmuramoyl- l -alanine: d -glutamate Ligase (MurD)

Journal of Medicinal Chemistry, 2011

Identification of an Inhibitor of the MurC Enzyme, Which Catalyzes an Essential Step in the Peptidoglycan Precursor Synthesis Pathway

Charlene Desbonnet, Thomas Dougherty

ASSAY and Drug Development Technologies, 2008

Evaluation of the published kinase inhibitor set to identify multiple inhibitors of bacterial ATP-dependent mur ligases

Journal of Enzyme Inhibition and Medicinal Chemistry, 2019

Design and Synthesis of Novel N-Benzylidenesulfonohydrazide Inhibitors of MurC and MurD as Potential Antibacterial Agents

Slavko Pečar

Molecules, 2008

Virtual screening for potential inhibitors of bacterial MurC and MurD ligases

Gerhard Klebe

Journal of Molecular Modeling, 2012

A MurF Inhibitor That Disrupts Cell Wall Biosynthesis in Escherichia coli

Ignatius Turchi

Antimicrobial Agents and Chemotherapy, 2007

Full Paper Design and Synthesis of Novel N-Benzylidenesulfonohydrazide Inhibitors of MurC and MurD as Potential Antibacterial Agents

Rok Frlan

2008

Phage display-derived inhibitor of the essential cell wall biosynthesis enzyme MurF

C. Paradis-bleau

BMC Biochemistry, 2008

Design, synthesis and evaluation of second generation MurF inhibitors based on a cyanothiophene scaffold

Chris Randall

European journal of medicinal chemistry, 2013

Macrocyclic inhibitors of the bacterial cell wall biosynthesis enzyme mur D

Ian Chopra

Bioorganic & Medicinal Chemistry Letters, 2003

Discovery of new MurA inhibitors using induced-fit simulation and docking

Bioorganic & Medicinal Chemistry Letters, 2017

Novel 2-thioxothiazolidin-4-one inhibitors of bacterial MurD ligase targeting d-Glu- and diphosphate-binding sites

European Journal of Medicinal Chemistry, 2011

3,5-Dioxopyrazolidines, Novel Inhibitors of UDP-N- Acetylenolpyruvylglucosamine Reductase (MurB) with Activity against Gram-Positive Bacteria

Tarek Mansour

Antimicrobial Agents and Chemotherapy, 2006

Identification of novel inhibitors of Pseudomonas aeruginosa MurC enzyme derived from phage-displayed peptide libraries

Roger C . Levesque

Journal of Antimicrobial Chemotherapy, 2003

Design of Inhibitors of the MurF Enzyme of Streptococcus pneumoniae Using Docking, 3D-QSAR, and de Novo Design

Santosh Khedkar

Journal of Chemical Information and Modeling, 2007

Discovery of MurA Inhibitors as Novel Antimicrobials through an Integrated Computational and Experimental Approach

Yanhong Liu

Antibiotics

Pyrazolopyrimidines Establish MurC as a Vulnerable Target in Pseudomonas aeruginosa and Escherichia coli

David McKinney

ACS Chemical Biology, 2014