Substrates of IAP Ubiquitin Ligases Identified with a Designed Orthogonal E3 Ligase, the NEDDylator (original) (raw)
Identification of a Novel Anti-apoptotic E3 Ubiquitin Ligase That Ubiquitinates Antagonists of Inhibitor of Apoptosis Proteins SMAC, HtrA2, and ARTS
DEUG Y. SHIN
Journal of Biological Chemistry, 2013
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Ubiquitylation in apoptosis: a post-translational modification at the edge of life and death
Vishva Dixit
Nature Reviews Molecular Cell Biology, 2011
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To fight or die — inhibitor of apoptosis proteins at the crossroad of innate immunity and death
juanita lopez
Current Opinion in Cell Biology
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Caspase-mediated cleavage of the ubiquitin-protein ligase Nedd4 during apoptosis
Julie Robinson
Journal of Biological …, 1998
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The E3 Ubiquitin Ligase cIAP1 Binds and Ubiquitinates Caspase-3 and -7 via Unique Mechanisms at Distinct Steps in Their Processing
Srinivas MALLADI
Journal of Biological Chemistry, 2009
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Systematic In Vivo RNAi Analysis Identifies IAPs as NEDD8-E3 Ligases
John Silke
Molecular Cell, 2010
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New insights into the role of the ubiquitin-proteasome pathway in the regulation of apoptosis
Alfred Goldberg
Chang Gung medical journal
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Ubiquitin binding modulates IAP antagonist-stimulated proteasomal degradation of c-IAP1 and c-IAP21
Domagoj Vucic
Biochemical Journal, 2009
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Delineating Crosstalk Mechanisms of the Ubiquitin Proteasome System That Regulate Apoptosis
Nishant Kumar Varshney
Frontiers in cell and developmental biology, 2018
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Identification of mammalian mitochondrial proteins that interact with IAPs via N-terminal IAP binding motifs
Paul Ekert
Cell Death and Differentiation, 2007
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Regulation of apoptosis by XIAP ubiquitin-ligase activity
Hermann Steller
Genes & Development, 2008
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X-linked Inhibitor of Apoptosis Protein promotes the degradation of its antagonist, the pro-apoptotic ARTS protein
Yossi Gottfried
… International Journal of …, 2011
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Apoptosis-Inducing Factor Is a Target for Ubiquitination through Interaction with XIAP
John Wilkinson
Molecular and Cellular Biology, 2008
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An IAP-IAP Complex Inhibits Apoptosis
Temesgen Samuel
Journal of Biological Chemistry, 2004
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The deubiquitinase Usp27x as a novel regulator of cFLIPL protein expression and sensitizer to death-receptor-induced apoptosis
Arnim Weber
Apoptosis, 2022
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Human inhibitor of apoptosis proteins: why XIAP is the black sheep of the family
brendan eckelman
Embo Reports, 2006
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Targeting Inhibitors of Apoptosis Proteins (IAPs) For New Breast Cancer Therapeutics
liu liu
Journal of Mammary Gland Biology and Neoplasia, 2012
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Structures of the cIAP2 RING domain reveal conformational changes associated with ubiquitin-conjugating enzyme (E2) recruitment
Clyde Smith
Journal of Biological …, 2008
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ARTS binds to a distinct domain in XIAP-BIR3 and promotes apoptosis by a mechanism that is different from other IAP-antagonists
Anna Shekhtman, Prof. Sarit Larisch
Apoptosis, 2011
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Regulation of Apoptosis by Inhibitors of Apoptosis (IAPs)
Jean Berthelet, Dubrez L
2013
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Distinct roles for the cellular inhibitors of apoptosis proteins 1 and 2
Tyson Graber
Cell Death and Disease, 2011
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Mule/ARF-BP1, a BH3-Only E3 Ubiquitin Ligase, Catalyzes the Polyubiquitination of Mcl-1 and Regulates Apoptosis
Qing Zhong
Cell, 2005
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The RING Domain of cIAP1 Mediates the Degradation of RING-bearing Inhibitor of Apoptosis Proteins by Distinct Pathways
Chris Kern, Robert Korneluk
Molecular Biology of the Cell, 2008
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Ubiquitination profiling identifies sensitivity factors for IAP antagonist treatment
Alexandre Masselot
Biochemical Journal, 2015
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Identification of a conserved anti-apoptotic protein that modulates the mitochondrial apoptosis pathway
Reiner Jänicke, Marshall Anderson
PloS one, 2011
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The Apoptosis Inhibitor ARC Undergoes Ubiquitin-Proteasomal-mediated Degradation in Response to Death Stimuli: IDENTIFICATION OF A DEGRADATION-RESISTANT MUTANT
Yun Tae Nam
Journal of Biological Chemistry, 2007
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SAG/ROC-SCFβ-TrCP E3 Ubiquitin Ligase Promotes Pro-Caspase-3 Degradation as a Mechanism of Apoptosis Protection
JUN LI
Neoplasia, 2006
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Molecular Sciences Modification by Ubiquitin-Like Proteins: Significance in Apoptosis and Autophagy Pathways
Monde Ntwasa
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FAIM-L Is an IAP-Binding Protein That Inhibits XIAP Ubiquitinylation and Protects from Fas-Induced Apoptosis
Joan Comella
Journal of Neuroscience, 2013
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IAPs – the ubiquitin connection
John Silke
Cell Death and Differentiation, 2005
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Structural Analysis of the UBA Domain of X-linked Inhibitor of Apoptosis Protein Reveals Different Surfaces for Ubiquitin-Binding and Self-Association
Kong Hung SZE
PLOS One, 2011
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Regulation of the Proapoptotic ARTS Protein by Ubiquitin-mediatedDegradation
John Finberg
Journal of Biological Chemistry, 2005
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Uncoupling of the Signaling and Caspase-inhibitory Properties of X-linked Inhibitor of Apoptosis
Shawn Bratton, Ezra Burstein
Journal of Biological Chemistry, 2004
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