Laryngeal chondrosarcoma: A systematic review of 592 cases (original) (raw)
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Laryngeal chondrosarcoma: a report of five cases
European Archives of Oto-Rhino-Laryngology, 2002
Laryngeal chondrosarcoma is a rare tumor that is known for its indolent course and its tendency to ultimate recurrence. According to the actually adopted classification, 95% of the reported cases are of a low-grade type. A consensus recognizing conservative surgery as the most reasonable treatment for these lesions has almost been reached. However, fear of jeopardizing the patency of the laryngeal airway as a result of a wide cricoid excision and also the fear of repeated recurrences could still push some surgeons to perform a total laryngectomy in the case of laryngeal chondrosarcoma. After a brief review of the literature, we will present five cases of laryngeal chondrosarcoma that were treated and followed at the Clermont-Ferrand University Medical Center over the last two decades. These cases exhibit many of the clinicopathologic features of the tumor and illustrate the pitfalls of diagnosis and treatment. In light of this presentation, we will discuss the widely accepted management as well as a newly suggested treatment modality for this disease.
Laryngeal chondrosarcoma: report of two cases
European annals of otorhinolaryngology, head and neck diseases, 2011
The present study describes the clinical, radiological and histological features of laryngeal chondrosarcoma, on the basis of two clinical cases, and discusses management. Two male patients, aged 63 and 51 years, presented with low-grade chondrosarcoma revealed respectively by a mass in the lateral neck and by laryngeal dyspnea. CT showed a tumoral process with calcification, developed from the thyroid and cricoid cartilage, respectively. The first patient underwent partial and the second total laryngectomy. Chondrosarcoma is diagnosed on the basis of combined clinical, radiological and histological signs. Differential diagnosis with chondroma may be difficult, especially in grade-1 chondrosarcoma. Laryngeal chondrosarcoma is a rare tumor. Management is basically surgical. Prognosis is generally good, depending essentially on histologic grade.
Chondrosarcoma of Larynx: A Case Report with Review of Literature
2015
In spite of being the most common nonepithelial neoplasm, chondrosarcoma makes up only about 0.2% of all head and neck malignancies and approximately 1% of all laryngeal tumors. Primary laryngeal chondrosarcoma is rare with only 300 cases being reported in literature. Herein, we present a case of 61-year old male who presented with long-standing neck mass. Histopathological exami nation, revealed it to be a chondrosarcoma arising from cricoid cartilage of larynx. Microscopic features with differential diagnoses and review of literature is being discussed.
A Rare Case of Malignant Tumor of the Larynx with Good Prognosis: Laryngeal Chondrosarcoma
Case Reports in Oncological Medicine, 2019
Laryngeal chondrosarcoma is a rare laryngeal tumor that most frequently originates from the cricoid cartilage. The majority of lesions are low grade and the distinction from benign chondromas must be made. We present a case of a laryngeal chondrosarcoma arising from the cricoid cartilage in a 75-year-old Arab man who presented with hoarseness, dysphonia, and dyspnea. Endoscopic and radiological examinations showed a mass of the wall of his larynx with displaced structures, airway obstruction, and destruction of the cartilage. The patient underwent total laryngectomy. Histological examination supported the diagnosis of low-grade chondrosarcoma. Five months later, the radiological and clinical findings showed no evidence of recurrence or metastases. Laryngeal chondrosarcomas remain a rare disease of unknown etiology, with slow and insidious symptoms. The treatment is surgical, given the importance of preserving the larynx to patients’ quality of life. The prognosis is favorable and me...
Laryngeal chondrosarcoma: is conservative surgery adequate treatment?
The Journal of Laryngology & Otology, 1989
A case of laryngeal chondrosarcoma in a 63-year-old woman is presented. The report illustrates most of the features of this rare neoplasm, the difficulties in the histopathological evaluation and supports the previous ones that recommend an initial conservative attitude towards low grade laryngeal chondrosarcomas.
Annals of Diagnostic Pathology, 2004
We studied 19 cases of chondroid tumors of the larynx: two chondrometaplastic nodules, two chondromas and 15 chondrosarcomas (including two dedifferentiated chondrosarcomas). One of chondromas recurred 18 months after resection because of inadequate surgical treatment. Chondrosarcomas were separated as low-grade (nine cases), intermediate (three cases), high-grade (one case), and dedifferentiated (two cases) according to histologic appearance. Chondrosarcomas are nearly always histologically low grade, make up the largest numbers of the neoplasms, and arise from the cricoid cartilage. Conservative surgical management, when possible, is advocated to preserve the larynx. Chondrometaplastic nodules are to be distinguished from chondrosarcoma and the rarely occurring chondroma. The nodules are not neoplastic and have a low to nil recurrent potential.
Laryngeal chondrosarcoma of the thyroid cartilage
Türk Patoloji Dergisi, 2020
Laryngeal chondrosarcoma is rare and accounts for 0.2% of all larynx malignancies. Although chondrosarcoma is the most common sarcoma seen in the larynx, laryngeal involvement by cartilage tumors is rare. In this article, we aimed to present the differential diagnosis of chondrosarcoma located in the thyroid cartilage, which is a rare site, in a 75-year-old male patient. The patient underwent total laryngectomy by the otolaryngology department. The macroscopy of the laryngectomy material sent to the pathology laboratory revealed a 3x2 cm tumor with a polypoid extension to the lumen from the bottom of the right vocal cord. Although clinical and radiological findings are important in the diagnosis, the definite diagnosis is based on the pathological examination. It is especially important to differentiate the lesion from chondromas.
Chondrosarcoma of the thyroid cartilage: a rare laryngeal malignancy
Laryngeal chondrosarcoma is a rare malignant tumor that arises from the cartilaginous structures of the larynx. It is a slow-growing neoplasm with high tendency to locoregional recurrence after treatment. Surgery is the primary treatment. Prognosis depends on histological differentiation degree and quality of surgical excision which can be very mutilating. Distant metastatis can occur in cases of histological high-grade tumors. From a new observation and a review of the literature, we discuss the clinical characteristics, therapeutic modalities and patient outcomes.
Laryngeal Chondrosarcoma: an Exceptional Localisation of a not Unfrequent Bone Tumor
Sarcoma, 2009
After osteosarcoma, chondrosarcoma is the second most common primary bone tumor accounting for 26% of all malignancies. In the laryngeal region however, chondrosarcomas are rather rare. Only 300 cases are reported in literature. Considering laryngeal chondrosarcoma, about 75% occur in the cricoid cartilage, whereas 20% occur in the thyroid cartilage. In this paper we report a case of thyroidal chondrosarcoma, and based on a thorough literature search we suggest some practical guidelines concerning diagnosis and therapy.
Laryngeal Chondrosarcoma: An Exceptional Localisation of a Not Unfrequent Bone
2013
After osteosarcoma, chondrosarcoma is the second most common primary bone tumor accounting for 26 % of all malignancies. In the laryngeal region however, chondrosarcomas are rather rare. Only 300 cases are reported in literature. Considering laryngeal chondrosarcoma, about 75 % occur in the cricoid cartilage, whereas 20 % occur in the thyroid cartilage. In this paper we report a case of thyroidal chondrosarcoma, and based on a thorough literature search we suggest some practical guidelines concerning diagnosis and therapy. Copyright © 2009 Mieke Moerman et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. 1.