The effect of ion implantation on cellular adhesion (original) (raw)
Related papers
Biological Tissue Adhesion to Ion Implanted Surfaces
MRS Proceedings, 1987
ABSTRACTResults of preliminary investigations on varying the adhesion and growth behaviour of osteoblast-like cells on silicon are presented. Significant changes in growth behaviour are obtained by implanting oxygen or by growing a thermal oxide on the surface. The objective of the work is to modify tissue adhesion to materials used as prosthetic devices.
Adhesion of bone cells to ion-implanted titanium
Journal of materials science. Materials in medicine, 2003
The use of ion-implantation to encourage osseointegration has been investigated using an in vitro model cell culture system and surface analysis. Polished titanium discs were implanted with calcium, potassium and argon ions. The adhesion of bone-derived cells was measured using radioactively labeled cells and the morphology examined using scanning electron microscopy. Similar numbers of cells were found to adhere to the potassium and argon-implanted titanium as to control (non-implanted) titanium. However, adhesion to the calcium-implanted titanium discs was significantly reduced. Moreover, although the cells were found to be well spread on the calcium and potassium-implanted titanium, a much greater proportion of cells appeared to remain rounded and poorly attached on the argon-implanted surface. These differences are discussed in relation to the observed surface roughness and chemistry, which were assessed using interferometry and X-ray photoelectron spectroscopy, respectively.
Cell attachment on ion implanted titanium surface
2008
Of outmost importance for the successful use of an implant is a good adhesion of the surrounding tissue to the biomaterial. In addition to the surface composition of the implant, the surface topography also influences the properties of the adherent cells. In the present investigation, ion implanted and untreated surfaces were compared for cell adhesion and spreading. The surface topography of the surfaces were analyzed using AFM and the cell studies with SEM. The results of our present investigation is indicative of the fact that ion implanted titanium surface offer better cell binding affinity compared to untreated/polished surface.
The International journal of oral & maxillofacial implants, 2010
PURPOSE This paper reports on an in vitro comparison of osteoblast and mesenchymal stem cell (MSC) adhesion, proliferation, and differentiation related to two different surface treatments applied to the same implant design to determine whether the interaction between cells and implants is influenced by surface structure and chemical composition of the implants. MATERIALS AND METHODS Thirty-nine implants with a sandblasted (SB) surface and 39 implants with a grit-blasted and high-temperature acid-etched (GBAE) surface were used. The implant macrostructures and microstructures were analyzed by high- and low-voltage scanning electron microscopy (SEM) and by stereo-SEM. The surface chemical composition was investigated by energy dispersive analysis and x-ray photoemission spectroscopy. SaOS-2 osteoblasts and human MSCs were used for the evaluation of cell proliferation and alkaline phosphatase enzymatic activity in contact with the two surfaces. RESULTS The GBAE surface showed fewer con...