Impact of Pulmonary Rehabilitation on Exercise Tolerance and Quality of Life in Patients With Idiopathic Pulmonary Fibrosis (original) (raw)
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Respiration; international review of thoracic diseases, 2014
Idiopathic pulmonary fibrosis (IPF) is a chronic, devastating, interstitial lung disease, with few therapeutic options. IPF is characterized by pulmonary restriction, dyspnea, hypoxemia, exercise intolerance and poor quality of life (QOL). We aimed to examine the effect of exercise training (ET) on clinical outcomes in IPF patients. A randomized controlled study included thirty-two IPF patients (aged 68 ± 8 years) who were allocated either to the ET group (n = 15), participating in a 12-week, twice-weekly 60-min supervised ET-based pulmonary rehabilitation program, or to a control group (n = 17) continuing with regular medical treatment alone. Cardiopulmonary exercise test, 6-min walking distance (6MWD) test, 30-second chair-stand test, pulmonary function tests, dyspnea and QOL were assessed at baseline and at the end of the 12-week intervention. Significant differences were observed between the ET and the control groups in raw mean deltas (Δ = post- - pre-intervention): Δ6MWD, 81 m...
Iranian Rehabilitation Journal
Objectives: Idiopathic pulmonary fibrosis (IPF) is characterized by progressively worsening lung function, ventilation capacity, dyspnea, and finally reduced exercise intolerance. All of these have a significant negative impact on functional capacity and quality of life. In this study, we aim to evaluate the effects of pulmonary rehabilitation (PR) in IPF and assess the predictors of success. Methods: Data from 17 IPF patients who completed the program from the total of 27 patients who applied to PR were used in our study. We evaluated their pulmonary function tests, exercise capacity, peripheral-respiratory muscle strength, body composition, quality of life, and psychological states before and after PR. Results: Following the PR program, improvements over the minimal clinically important differences were observed in almost all parameters compared to the baseline; however, statistically significant improvements were only observed in the medical research council (P=0.020), the St. Ge...
The Role of Pulmonary Rehabilitation in Patients with Idiopathic Pulmonary Fibrosis
Interstitial Lung Diseases [Working Title], 2019
Idiopathic pulmonary fibrosis (IPF) is known as one of the most severe lung conditions and the worst form of interstitial lung disease (ILD). There is a continuing concern about clinical research to identify new therapies that influence the quality of life in patients diagnosed with this chronic progressive pulmonary disease, with an average survival of 3-5 years. Although in recent years great progress has been made to slow down the functional decline of the disease with new antifibrotic therapies, it has failed to alter the prognosis and survival of IPF patients. Clinical trials and recent ATS/ERS guidelines have brought at least moderate and low levels of evidence for increased effort tolerance, decreased symptoms, and improved quality of life following participation in lung rehabilitation programs for ILD patients and in particular those with IPF. Pulmonary rehabilitation has been shown to be a standard of care for COPD patients, but their personalized application to patients with IPF has had positive short-term results, becoming a safe alternative to non-pharmacological treatment. The chapter includes the general objectives of rehabilitation programs, their type and structure, ways of complex assessment of patients before and after a training exercise, types of exercises, and short-and long-term results.
Iranian Rehabilitation Journal, 2022
Idiopathic pulmonary fibrosis (IPF) is characterized by progressively worsening lung function, ventilation capacity, dyspnea, and finally reduced exercise intolerance. All of these have a significant negative impact on functional capacity and quality of life. In this study, we aim to evaluate the effects of pulmonary rehabilitation (PR) in IPF and assess the predictors of success. Methods: Data from 17 IPF patients who completed the program from the total of 27 patients who applied to PR were used in our study. We evaluated their pulmonary function tests, exercise capacity, peripheral-respiratory muscle strength, body composition, quality of life, and psychological states before and after PR. Results: Following the PR program, improvements over the minimal clinically important differences were observed in almost all parameters compared to the baseline; however, statistically significant improvements were only observed in the medical research council (P=0.020), the St. George respiratory questionnaire (P=0.002), the maximal inspiratory pressure (P=0.024), the anxiety score (P=0.001), the depression score (P=0.002), and the right quadriceps muscle strength (P=0.046). There was only a statistically significant negative correlation between the initial forced vital capacity and the forced expiratory volume in one-second value with the increase in patients' maximal inspiratory pressure values after PR. Discussion: After a multidisciplinary, comprehensive PR program, dyspnea sensation, exercise capacity, endurance time, quality of life, respiratory and peripheral muscle strengths, and psychological status were improved regardless of age, gender, antifibrotic treatment, and comorbidities. Therefore, patients should be referred to PR units before the deterioration in the quality of life in the early stages of the disease.
Effect of home-based pulmonary rehabilitation in patients with idiopathic pulmonary fibrosis
Multidisciplinary Respiratory Medicine, 2010
The aim of this study was to investigate the effects of a home-based pulmonary rehabilitation program on the functional outcome parameters in patients with idiopathic pulmonary fibrosis (IPF). Design: A prospective study. Patients: Seventeen patients diagnosed with IPF. Methods: A home-based pulmonary rehabilitation program was carried out in 17 IPF patients for 12 weeks. Dyspnea severity during daily life activities (Medical Research Council Scale), pulmonary function (pulmonary function test), exercise capacity (6-minute walking test, 6MWD), and general health related quality of life (Medical Outcomes Short Form-36) were evaluated. Results: A significant decrease in perceived dyspnea (p = 0.003) and leg fatigue (p < 0.05) severities, and an increase in the 6MWD (p = 0.04) and general health related quality of life scores (health perception, physical role, and emotional status subscores) were found after the program (p < 0.05). Conclusion: Home-based pulmonary rehabilitation may reduce dyspnea and fatigue severities, and improve exercise capacity and health-related quality of life in patients with IPF. In the treatment of IPF patients, home-based pulmonary rehabilitation programs should be placed alongside the routine treatment options.
Value of pulmonary rehabilitation in patients with idiopathic pulmonary fibrosis
Egyptian Journal of Chest Diseases and Tuberculosis, 2014
Background: Idiopathic pulmonary fibrosis (IPF) is a chronic lung condition of uncertain etiology that causes progressive shortness of breath, cough, reduced exercise tolerance and quality of life. This may, at least in part, be due to daily physical inactivity. Therefore symptomatic patients with lung fibrosis may be good candidates for comprehensive pulmonary rehabilitation (PR) programs. Aim of work: To evaluate the role of PR program in improving the functional status and dyspnea scale in patients with IPF. Patients and methods: Thirty patients had IPF, according to the recent consensus statement, were subjected to PR program that mainly consisted of three sessions per week for 8 week duration. The program basically consisted of upper and lower extremity exercises, breathing exercise, and chest physical therapy. Psychological support and patient education rounded out the program. Spirometery, diffusion capacity of the lung for carbon monoxide [DLco], arterial blood gas analysis, 6-minute walking distance (6MWD), dyspnea rating with the Modified Borg Scale (MBS) and health-related quality of life (HRQL) score using the St. George's Respiratory Questionnaire (SGRQ) score were evaluated at baseline, after 4 weeks and at the end of the eighth week of the program. Results: There were significant improvement in dyspnea score (P = 0.001), 6MWD (P = 0.001), % predicted of forced vital capacity (FVC% predicted) (P = 0.001) and HRQL (P = 0.001). However, arterial blood gas values and DLco showed no significant improvement at the end of the program. Conclusions: PR improves dyspnea score, exercise capacity and HRQL in patients with IPF.
2021
BackgroundIdiopathic pulmonary fibrosis (IPF) is one of the common types of interstitial lung disease having high prevalence and mortality worldwide. As a result of patient-centred hindering factors of adherence to centre-based pulmonary rehabilitation (PR), home-based PR is an alternate mode of rehabilitating individuals with IPF. This systematic review will evaluate the effectiveness of unsupervised home-based PR on functional capacity and health-related quality of life (HRQoL) in individuals with IPF. MethodsClinically stable, high resolution computed tomography and physician diagnosed IPF participants having modified Medical Research Council score below five will be considered for the systematic review. Studies involving home-based PR as an intervention to treat individuals with IPF will be considered. Randomised controlled trials and quasi-randomised studies (with two groups followed-up) are eligible to be included. Outcomes of our interest are functional capacity (6-minute wal...
https://www.ijhsr.org/IJHSR\_Vol.9\_Issue.12\_Dec2019/IJHSR\_Abstract.011.html, 2019
Interstitial lung disease (ILD) is an umbrella term which consists of variety of disorders. ILDs are characterized by impaired gas exchange function and restricted pattern on lung function physiology testing with associated radiological findings. Lung damage occurring in most ILDs is progressive and irreversible Idiopathic Pulmonary Fibrosis (IPF) is one of the commonest ILD encountered in practice. The symptoms experienced by the patients in most interstitial lung disease are cough, breathlessness or shortness of breath, limited functional capacity. Here, we identified a case study of Idiopathic Pulmonary Fibrosis for which a tailor-made pulmonary rehabilitation program was introduced. The 8 week pulmonary rehabilitation program showed significant improvement in the aerobic capacity and quality of life of the patient.
Open Journal of Respiratory Diseases, 2021
Idiopathic pulmonary fibrosis (IPF) is a chronic, life-limiting with an average life expectancy of 05 years following the onset of the disease, with no curative treatments. These patients need palliative care and rehabilitation is one of the methods that can be used to improve quality of life (QoL) among these patients. Yet the research conducted to assess benefits of pulmonary rehabilitation (PR) in terms of improving physical activity and QoL in IPF patients remains limited. Hence this study aims to evaluate the effect of a bespoke pulmonary rehabilitation programme, on the physical, physiological and psychological parameters and improvements of QoL among IPF patients. Eleven (11) subjects with IPF received 6 weeks of pulmonary rehabilitation. An interviewer administered quality of life questionnaire, six-minute walking test (6MWT), Incremental bicycle exercise tests were performed, and cardiac and respiratory parameters were assessed pre-and post-rehabilitation. The 6MWT was significantly increased following training (Pre 312.55 ± 89.99; Post, 380.73 ± 59.60). A significant improvement was observed in overall QoL (2.226 ± 0.026), dyspnoea (−0.455 ± 0.004) anxiety (−2.070 ± 0.038), depression (−2.217 ± 0.027) scores. No significant changes were found in the VO 2 max and other cardiopulmonary parameters, while non-significant improvement was seen in SpO 2 at peak exercise from 85.8-86.5.
Balneo Research Journal, 2020
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, fatal lung disease with a median survival rate of 2-4 years after diagnosis, occurring primarily in older adults. The diagnosis is suggested by histology or radiologic evidence of a usual interstitial pneumonia (UIP) pattern and exclusion of known cases of pulmonary fibrosis. There are some comorbidities associated with IPF such as pulmonary hypertension, emphysema, chronic obstructive pulmonary disease (COPD), asthma, lung cancer, cardiovascular disorders, gastroesophageal reflux disease (GERD), sleep disorders and psychiatric disturbances. The management of IPF focuses on the amelioration of symptoms, preserving lung function, improving health status, minimizing the adverse effects of therapy and improving survival. Pulmonary rehabilitation is suggested for IPF patients when adequate medical therapy controls poorly the disease progression and mental, physical or social consequences of the illness persist during daily l...