original ) (raw )In vitro cytotoxicity of GC sequence directed alkylating agents related to distamycin
Maurizio D'Incalci
Journal of Medicinal Chemistry, 1993
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Bioorganic & Medicinal Chemistry, 2010
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A novel achiral seco-cyclopropylpyrido [e] indolone (CPyI) analog of CC-1065 and the duocarmycins: Synthesis, DNA interactions, in vivo anticancer and anti-parasitic …
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Bioorganic & medicinal …, 2010
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Hybrid molecules based on distamycin A as potential antitumor agents
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Arkivoc, 2005
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Effect of Buthionine Sulfoximine and Ethacrynic Acid on Cytotoxic Activity of Mitomycin C Analogues BMY 25282 and BMY 250671
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Binding of saframycin A, a heterocyclic quinone anti-tumor antibiotic to DNA as revealed by the use of the antibiotic labeled with [ 14C]tyrosine or [ 14C]cyanide
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Journal of Biological Chemistry
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Systematic exploration of the structural features of yatakemycin impacting DNA alkylation and biological activity
Mark Tichenor
Journal of the American Chemical Society, 2007
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The Development of New DNA Alkylating Antitumour Agents Modeled on the Natural Product CC-1065
LEESA SWAN
2018
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Pier Giovanni Baraldi
Bioorganic & Medicinal Chemistry Letters, 2009
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Stereoelectronic factors influencing the biological activity and DNA interaction of synthetic antitumor agents modeled on CC1065
LI Patrick
Journal of Medicinal Chemistry, 1988
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Role of the acyl groups in carbohydrate chains in cytotoxic properties of olivomycin A
Vladimir Kuzmin
The Journal of Antibiotics, 2013
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Synthesis and evaluation of duocarmycin SA analogs incorporating the methyl 1,2,8,8a-tetrahydrocyclopropa[c]oxazolo[2,3-e]indol-4-one-6-carboxylate (COI) alkylation subunit
Kristopher Boyle
Bioorganic & Medicinal Chemistry Letters, 2010
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Antibody‐Directed Enzyme Prodrug Therapy: A Promising Approach for a Selective Treatment of Cancer Based on Prodrugs and Monoclonal Antibodies
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Chemical Biology & Drug Design, 2009
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Selective Treatment of Hypoxic Tumor Cells In Vivo: Phosphate Pre-Prodrugs of Nitro Analogues of the Duocarmycins
Shangjin Yang
Angewandte Chemie International Edition, 2011
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Dependence of DNA Sequence Selectivity and Cell Cytotoxicity on Azinomycin A and B Epoxyamide Stereochemistry
Stefano Alcaro
Organic Letters, 2007
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Designing DNA Binding Antitumor Antibiotics With Structure Determination: A Systems Approach
Prateek Pandya
2008
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Selective DNA interaction of the novel distamycin derivative FCE 24517
Maurizio Dincalci
Cancer Research, 1991
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Synthesis and antitumor properties of new glycosides of daunomycinone and adriamycinone
Federico Arcamone
Journal of Medicinal Chemistry, 1975
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Optimization of macromolecular prodrugs of the antitumor antibiotic adriamycin
J. Greve
Journal of Controlled Release, 1985
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Isomer-dependent daunomycin release and in vitro antitumour effect of< i> cis-aconityl-daunomycin
Ferenc Hudecz
2003
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Antitumor Potential of Conjugable Valinomycins Bearing Hydroxyl Sites: In Vitro Studies
Caterina Fusco
ACS Medicinal Chemistry Letters, 2013
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Comparison of dna scission and cytotoxicity produced by adriamycin and 5-iminodaunorubicin in human colon carcinoma cells
Linda Lloyd
Biochemical Pharmacology, 1983
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High resolution solution structure of a DNA duplex alkylated by the antitumor agent duocarmycin SA 1 1 Edited by I. Tinoco
Jan Rydzewski
Journal of Molecular Biology, 1997
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Isomer-dependent daunomycin release and in vitro antitumour effect of cis-aconityl-daunomycin
Sára TÓTH
Biochemical and Biophysical Research Communications, 2003
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Schedule-dependent enhancement of antitumor activity of ethyldeshydroxy-sparsomycin in combination with classical antineoplastic agents
dick de vos
Anti-Cancer Drugs, 1995
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The structural basis for in situ activation of DNA alkylation by duocarmycin SA
David A Case
Journal of Molecular Biology, 2000
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High resolution solution structure of a DNA duplex alkylated by the antitumor agent duocarmycin SA
Jarrod Smith
Journal of Molecular Biology, 1997
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Synthesis and antitumor activity of a new class of water soluble camptothecin derivatives
Walter Cabri
Bioorganic & Medicinal Chemistry Letters, 1996
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DNA damage and differential cytotoxicity produced in human carcinoma cells by CC-1065 analogues, U-73,975 and U-77,779
Neil Gibson
Cancer research, 1991
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Modification of olivomycin A at the side chain of the aglycon yields the derivative with perspective antitumor characteristics
Vladimir Kuzmin
Bioorganic & Medicinal Chemistry, 2011
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Synthesis, DNA-binding properties, and antitumor activity of novel distamycin derivatives [Erratum to document cited in CA110(19):173740j]
Nicola Mongelli
Journal of Medicinal Chemistry, 1989
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