Bone Marrow Transplantation (BMT) for Severe Aplastic Anemia (SAA): Results Obtained in 19 Patients (original) (raw)

11th Annual meeting of the EBMT, 1985

Abstract

10 adult patients and 9 children with SAA underwent allogeneic (17) or syngeneic (2) BMT. The median age was 17 years (range 4–37),all patients were pretransfused with a median of 7 units of red blood cells (range:2–50),15 of 19 patients had received platelet support with a median of 8 single donor platelet transfusions (range 1–29) The median duration of disease was 12 weeks (3–150).9 cases were classified as idiopathic,5 had a history of hepatitis,2 were previously exposed to Chloramphenicol and 2 cases were due to Novaminsulfone and Phenylbutazone,respectively.l patient had Fanconi-anemia.17 of 19 patients were pretreated with low-dose steroids,5 patients were also pretreated with androgens,without any success. Prior to BMT,16 patients had suffered from febrile episodes,all patients had experienced minor or major bleeding complications.

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