Activation of HERV-K(II) env by cAMP and EGF in different human cell lines (original) (raw)

2014

Abstract

<p>(<b>A</b>) Individual cell lines displayed differential constitutive HERV-K(II) <i>env</i> expression profiles. (<b>B</b>) Upon treatment of human fetal neurons, db-cAMP did not have any effects on HERV-K(II) <i>env</i> expression but EGF down-regulated HERV-K(II) expression. (<b>C</b>) U937 and (<b>D</b>) HFA showed decreased in HERV-K(II) <i>env</i> expression upon both db-cAMP and EGF exposure. (n = 4 replicates per group across two independent experiments).</p

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