Partial purification and properties of a haemolytic activity (T-lysin) from Aeromonas salmonicida (original) (raw)

An extracellular haemolytic activity, identified as T-lysin, was partially purified from the fish pathogen Aeromonas salmonicida and was shown to lyse trout erythrocytes through the combined action of caseinase and a membrane-associated factor. Incomplete lysis occurred in the absence of either component, indicating their cooperative effect on erythrocyte membranes. This study contributes to understanding the complex interrelationships between extracellular products of A. salmonicida relevant to its pathogenic mechanisms.