Motor function and the probability of prodromal Parkinson's disease in older adults (original) (raw)
BackgroundIdentification and characterization of Parkinson's disease (PD) in its prodromal stage is crucial.ObjectiveThe objective of this study was to investigate the association between motor function and the probability of prodromal PD in a community‐dwelling older population.MethodsWe used data from a population‐based cohort of older adults (HELIAD study). Subjective motor function was evaluated with a 12‐item motor symptoms questionnaire and objective motor function indirectly with a physical activity questionnaire and two gait speed tests. The probability of prodromal PD was calculated according to the Movement Disorder Society research criteria for n = 1731 without PD. Regression multiadjusted models were used to investigate the associations between each motor measure and prodromal PD probability.ResultsFor each unit increase in motor symptoms score and for each kcal/kg/day lower energy expenditure (corresponding to 20 minutes of light walking/day for a 75‐kg man) there w...
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